- Rheumatoid Arthritis Research and Therapies
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Vasculitis and related conditions
- Ocular Diseases and Behçet’s Syndrome
- Inflammatory Myopathies and Dermatomyositis
- Inflammasome and immune disorders
- Biosimilars and Bioanalytical Methods
- Retinal and Optic Conditions
- Psoriasis: Treatment and Pathogenesis
- Musculoskeletal pain and rehabilitation
- Adolescent and Pediatric Healthcare
- Peripheral Neuropathies and Disorders
- Transplantation: Methods and Outcomes
- Viral Infections and Immunology Research
- Sarcoidosis and Beryllium Toxicity Research
- Immunodeficiency and Autoimmune Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Monoclonal and Polyclonal Antibodies Research
- Systemic Lupus Erythematosus Research
- Eosinophilic Disorders and Syndromes
- Skin Diseases and Diabetes
- MicroRNA in disease regulation
- Biomarkers in Disease Mechanisms
Manisa Celal Bayar University
2020-2025
Dokuz Eylül University
2015-2018
Objectives: This study aims to investigate the effect of age on disease activity and biological treatment in patients with ankylosing spondylitis (AS). Patients methods: A total 811 AS registered TURKBIO registry database between 2011 2019 were categorized according their at time entry into assigned one two groups: young patients, defined as <60 years (n=610), those aged ≥60 (n=201) recorded elderly patients. Demographic, clinical, laboratory characteristics, along markers other follow-up...
Abstract Clinical data on the use of tumour necrosis factor inhibitors (TNFi) in late-onset ankylosing spondylitis (LoAS) are limited. The present study aimed to evaluate efficacy, safety, and treatment adherence associated with initial TNFi therapy biologic naive patients diagnosed LoAS. Patients whose age onset was ≥ 45 years < were classified as having LoAS YoAS, respectively, based symptom onset. There 2573 YoAS 281 Baseline disease activity measures similar between groups. No...
Abstract Objectives To assess the lung involvement in patients with Still’s disease, an inflammatory disease assessing both children and adults. exploit possible associated factors for parenchymal these patients. Methods A multicentre observational study was arranged consecutive characterized by among those included AIDA (AutoInflammatory Disease Alliance) Network Registry. disease-lung defined presence of pleuritis, features, acute respiratory distress syndrome (ARDS), and/or pulmonary...
Abstract Purpose of the present paper is to point out design, development and deployment AutoInflammatory Disease Alliance (AIDA) International Registry dedicated pediatric adult patients with Behçet’s disease (BD). The a clinical physician-driven non-population- electronic-based instrument implemented for retrospective prospective collection real-life data about demographics, clinical, therapeutic, laboratory, instrumental socioeconomic information from BD patients; based on Research...
TURKBIO registry, established in 2011, is the first nationwide biological database Turkey. This study aimed to provide an overview of data collected by June 2018.The registry included adult patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), nonradiographic axial spondyloarthritis (nr-AxSpA), and psoriatic (PsA). Demographic clinical features, disease activity markers, other follow-up parameters, current previous treat- ments, adverse events were registered electronically...
In this present study, we aimed to perform the reliability and validity analyses of Turkish Form Short Form-12 version 2 (SF-12v2) in different groups patients.After permission for validation study Form, Optum provided authors validly translated SF-12v2. The was carried out rheumatological, psychiatric, surgical wards Manisa Celal Bayar University Hafsa Sultan Training Research Center between September 2019 June 2020. Taking possible dropouts into consideration, a total 136 patients (67...
Background/Objectives: CT-P13 is a biosimilar version of infliximab, monoclonal antibody. In individuals with ankylosing spondylitis (AS), has been shown to be effective and have well-tolerated safety profile. The aim this study was evaluate the long-term drug persistence, safety, efficacy infliximab in patients AS undergoing first-line (1st-line) later (≥2nd-line) treatment clinical practice. Methods: We performed an observational cohort that included based on biological database TURKBIO...
This study aims to assess the different predictors of renal and patient prognosis in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients with without involvement.A total 79 (51 males, 28 females; mean age: 57.3±14.2 years; range, 18 71 years) AAV between January 2006 November 2019 were retrospectively analyzed. Demographic laboratory data including complement 3 (C3) serum levels biopsy findings extracted from electronic printed medical records hospital...
Frequency of pulmonary hypertension in transthoracic echocardiography screening is not increased Takayasu arteritis: Experience from a single center Turkey Pulmonary (PH) and arterial (PAH) are same pathologies.PH pathological condition that may occur variety clinical situations, including PAH.Among many other causes, PAH represents the most prominent type PH.Other than PAH, various pathologies lung diseases, chronic hypoxia, thromboembolic diseases also cause occurrence precapillary...
Aydin, Ali Ekrem MD; Gunduz, Ozgul Sari, Ismail Saatci, Osman Yilmaz, Erkan Akkoc, Nurullah MD Author Information
Telephone surveys are less expensive and time-consuming for both interviewers interviewees, with similar or even higher response rates than face-to-face interviews. In rheumatology, telephone technique has been used in a number of epidemiologic studies. the present study, we conducted survey screening inflammatory back pain (IBP) community.One hundred seventy-two patients axial spondyloarthritis (axSpA) 25 chronic mechanical were included. A interview was by same physician using standardized...
<h3>Background:</h3> In rheumatology, vaccination is crucial, but patients, physicians, and other healthcare workers may not always recognize this in their day-to-day work. <h3>Objectives:</h3> To evaluate the awareness of rheumatology patients using biological targeted synthetic DMARDs, as well physicians professionals who follow them, investigate rates at beginning after relevant training. <h3>Methods:</h3> The study included rheumatic on a national registry, TURKBIO. measure level about...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of disease 19 (COVID-19) pandemic, which has affected entire world. The development COVID-19 vaccines helped to slow spread virus. However, as with against other infectious diseases, adverse events can occur vaccines. Here we present 3 cases arthritis following vaccination and a comprehensive review existing literature.
<title>Abstract</title> Many animal and human studies indicate that Boric Acid Calcium Fructoborate have effects on helper T cells in immunity. The aim of our study is to evaluate Treg (<italic>CD4</italic><sup><italic>+</italic></sup><italic>Foxp3</italic><sup><italic>+</italic></sup>) Th17 (<italic>CD4</italic><sup><italic>+</italic></sup><italic>Ror-γt</italic><sup><italic>+</italic></sup>) cell populations related cytokine levels mononuclear isolated from peripheral blood samples...
Giriş ve Amaç: Bozulmuş el fonksiyonu, sistemik skleroz (SSk) hastaların işlevselliği ile ilgili yaşam kalitesini bozar. Çalışmanın amacı, akciğer tutulumu olan SSk hastalarında elin sınırlı eklem hareketliliğini (LJM) değerlendirmektir. Gereç Yöntemler: 42 hastası, LJM "dua işareti" testi kullanılarak değerlendirildi pozitif negatif demografik özellikleri (cinsiyet, yaş hastalık süresi), laboratuvar sonuçları (ESH, CRP, ANA, anti-topoizomeraz I anti-sentromer) modifiye Rodnan cilt skoru...