A5102740223- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Psoriasis: Treatment and Pathogenesis
- Heart Failure Treatment and Management
- Autoimmune and Inflammatory Disorders Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Hepatitis C virus research
- Tuberculosis Research and Epidemiology
- Viral Infections and Immunology Research
- Dialysis and Renal Disease Management
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Orthopedic Infections and Treatments
- Glycogen Storage Diseases and Myoclonus
- Platelet Disorders and Treatments
- Social Media in Health Education
- Pharmacology and Obesity Treatment
- Otitis Media and Relapsing Polychondritis
- Hepatitis B Virus Studies
- Spinal Fractures and Fixation Techniques
- Immunodeficiency and Autoimmune Disorders
- Diet and metabolism studies
- Erythropoietin and Anemia Treatment
- Acute Kidney Injury Research
- Parkinson's Disease and Spinal Disorders
Erciyes University
2015-2024
Center for Rheumatology
2015
Kayser (Italy)
2015
Sivas Cumhuriyet Üniversitesi
2010-2012
Pamukkale University
2012
Inonu University
2006-2007
Turgut Özal Tıp Merkezi
2006
Abstract Clinical data on the use of tumour necrosis factor inhibitors (TNFi) in late-onset ankylosing spondylitis (LoAS) are limited. The present study aimed to evaluate efficacy, safety, and treatment adherence associated with initial TNFi therapy biologic naive patients diagnosed LoAS. Patients whose age onset was ≥ 45 years < were classified as having LoAS YoAS, respectively, based symptom onset. There 2573 YoAS 281 Baseline disease activity measures similar between groups. No...
TURKBIO registry, established in 2011, is the first nationwide biological database Turkey. This study aimed to provide an overview of data collected by June 2018.The registry included adult patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), nonradiographic axial spondyloarthritis (nr-AxSpA), and psoriatic (PsA). Demographic clinical features, disease activity markers, other follow-up parameters, current previous treat- ments, adverse events were registered electronically...
Background Cardiovascular complications are one of the most common and serious extraskeletal manifestations ankylosing spondylitis (AS). Infliximab, a monoclonal antibody against tumor necrosis factor, is widely used in treatment AS. QT dispersion (QTd), which relates to left ventricular function as an index cardiac dysrhythmia, may be useful prognostic guide. Early detection possible involvement not clinically evident, whereas it detected by electrocardiography. Objectives The aim this...
Cardiovascular complications are one of the most common and serious extraskeletal manifestations ankylosing spondylitis (AS). Infliximab, a monoclonal antibody against tumor necrosis factor, is widely used in treatment AS. QT dispersion (QTd), which relates to left ventricular function as an index cardiac dysrhythmia, may be useful prognostic guide. Early detection possible involvement not clinically evident, whereas it detected by electrocardiography.The aim this prospective study was...
Objectives Patients with rheumatoid arthritis (RA) are known to be at increased cardiovascular risk. Etanercept is a tumor necrosis factor α (TNF-α) blocking agent that has been successfully used in the treatment of RA. We sought assess effects etanercept on cardiac functions and lipid profile RA patients without overt disease. Methods Sixteen active were recruited study prospectively. was administered subcutaneously twice week for 6 months. Clinical laboratory predictors activity evaluated...
An increase of brain natriuretic peptide (BNP) levels is commonly observed in patients on dialysis. Increased circulating BNP are related to future cardiac events and associated with shorter survival chronic hemodialysis (HD). During the first 1 or 2 years dialysis, peritoneal dialysis (PD) have been shown an improvement left ventricular hypertrophy, blood pressure, volume status. This study compares status PD HD without cardiovascular disease for less than 36 months. The correlation between...
<h3>Background</h3> Tumour necrosis factor inhibitors (TNFi) are efficacious in patients with axial spondyloarthritis (axSpA), but some switch to a different TNFi because of adverse effects (AE) or lack effect (LOE). The EuroSpA Collaboration has previously demonstrated 1-year retention rate 79% and 6 months LUNDEX adjusted BASDAI<4 59%<sup>1</sup> initiating the first treatment. Little is known about effectiveness switching second third axSpA. <h3>Objectives</h3> Firstly, investigate...
The reactivation of hepatitis B virus (HBV) infection is a well-known event in surface antigen (HbsAg)-positive patients receiving immunosuppressive therapy. objective this study was to assess the antiviral practice and course HBV inflammatory arthritis.Nineteen rheumatology centers participated retrospective study. HbsAg-positive who were taking disease-modifying antirheumatic drugs being tested for viral load at minimum two different time points included. case report form (CRF) consisted...
The aim of this study was to evaluate the impact obesity on treatment response secukinumab and drug survival rate in patients with ankylosing spondylitis (AS).
<h3>Background:</h3> In rheumatology, vaccination is crucial, but patients, physicians, and other healthcare workers may not always recognize this in their day-to-day work. <h3>Objectives:</h3> To evaluate the awareness of rheumatology patients using biological targeted synthetic DMARDs, as well physicians professionals who follow them, investigate rates at beginning after relevant training. <h3>Methods:</h3> The study included rheumatic on a national registry, TURKBIO. measure level about...
<h3>Background</h3> The first symptoms of ankylosing spondylitis (AS) patients usually begin prior to 45 years, but can occur later in life. <h3>Objectives</h3> purpose this study is evaluate the efficacy and safety anti-TNFα treatment late-onset AS (LoAS) comparison those with adult onset (AoAS). <h3>Methods</h3> We studied TURKBIO registry between dates January 2011 November 2018. All fulfilled modified New York criteria for <sup>1</sup> were classified into 2 groups based on their age at...
<h3>Background</h3> Rheumatoid arthritis (RA) and Ankylosing Spondylitis (AS) are the most common inflammatory rheumatic diseases. Comparing to healthy population, chronic kidney disease (CKD) might be more in these patients due complications such as amyloidosis or toxicity because of drug use. Anti-TNF treatment is an effective option treatments RA AS.There limited data whether anti-TNF efficient safe with AS. We summarized some early 9 this poster which was largest serie literature....
<h3>Background</h3> Comorbidities are frequent in Psoriatic arthritis (PsA) and can have an impact on morbidity mortality. <h3>Objectives</h3> We aimed to investigate the frequency of different comorbidities PsA, how PsA features which factors were associated with occurrence a large number patients, using PsART (Psoriatic Arthritis Registry Turkey)registry. <h3>Methods</h3> is national, web-based registry where consecutive patients recruited demographic, clinical therapeutic information...
Background. Recent evidence suggests that the activation of platelets and their interaction with circulating cells are important independent risk factors for atherosclerosis. In non-uremic patients symptomatic peripheral vascular disease, a relationship between serum homocysteine (Hcy) levels platelet activity had been reported. The purposes this study were to evaluate effects dialysis modality on in end-stage renal failure investigate activity, Hcy, left ventricular hypertrophy (LVH)....
ÖzAmaç: Psöriyatik artrit (PsA), spondiloartropati grubu hastalıklar içerisinde yer alan psöriyazis ile ilişkili bir hastalıktır.Psöriyaziste tanımlanan kardiyovasküler hastalık sıklığının artışının aynı zamanda PsA için de geçerli olduğu bilinmektedir.Fetuin-A, vasküler kalsifikasyon ve aterosklerozla ilişkisi gösterilmiş olan yeni biyobelirteçtir.Bu çalışmada PsA'da fetuin-A seviyelerinin parametreler ilişkisinin değerlendirilmesi amaçlandı.Yöntem: CASPAR kriterlerine göre tanı almış 97...
Anti-TNF antagonistleri bircok romatolojik hastaligin tedavisinde kullanilmaktadir. Bu grup ilaclarin en onemli yan etkileri ciddi enfeksiyon ve ikincil kanser varligi olarak bilinmektedir. Ancak anti-TNF tedavinin artmis riski ile iliskili oldugu konusundaki bilgiler net degildir. makalede tedavi arasindaki iliskiden bahsedilmektedir.
Background: Several factors such as effectiveness, safety and compliance affect the drug survival in chronic disorders. Physicians take care of long-term retention rate responses for discontinuation candidate drug. Identification predictors clinical response to certolizumab-pegol (CZP) may aid decision-making process treating patients psoriatic arthritis (PsA). Objectives: The purpose this study assess certolizumab pegol with PsA identify reasons discontinuation. Methods: Data on patient...
Background: Choosing the best treatment strategy for a patient is one of most difficult issues in modern rheumatology, as there are various factors affecting drug therapy chronic diseases, such efficacy, safety, and compliance. Physicians take care long-term retention rate responses discontinuation candidate drug. Objectives: The purpose this study to assess survival certolizumab pegol (CZP) patients with axial spondyloarthritis (ax-SpA) identify predictors reasons discontinuation. Methods:...
<h3>Objectives</h3> To evaluate the diagnostic and discriminative ability of new 2012 European League Against Rheumatism (EULAR)/American College Rheumatology (ACR) polymyalgia rheumatica (PMR) classification criteria compared to previous five diagnostic/classification for PMR in a multi-centre prospective study. <h3>Methods</h3> Patients older than 50 years age (n=163), presenting with onset (symptom duration ≤24 weeks) bilateral shoulder pain elevated acute phase reactants were enrolled...
<h3>Background</h3> Ankylosing Spondylitis (AS) is associated with a high disease burden. The greatest contributor to the burden loss of productivity. data on productivity in Turkish patients AS scarce. Work Productivity Survey (WPS) validated tool assess during preceding month, both at work and home. <h3>Objectives</h3> aim this study using WPS. <h3>Methods</h3> A total 397 (males:71.4%, mean age: 40.5, duration 6.8 years) from 19 rheumatology centers across Turkey were included study....