A5040248187- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Inflammasome and immune disorders
- Bone and Joint Diseases
- Hip disorders and treatments
- Eosinophilic Disorders and Syndromes
- Liver Disease Diagnosis and Treatment
- Pediatric health and respiratory diseases
- Dermatology and Skin Diseases
- Salivary Gland Disorders and Functions
- Myofascial pain diagnosis and treatment
- Musculoskeletal synovial abnormalities and treatments
- Sarcoidosis and Beryllium Toxicity Research
- Ophthalmology and Eye Disorders
- Biomarkers in Disease Mechanisms
- Pectus Deformity Diagnosis and Treatment
- Kidney Stones and Urolithiasis Treatments
- Dermatological and COVID-19 studies
- Therapeutic Uses of Natural Elements
- Hepatitis B Virus Studies
Istanbul Medeniyet University
2014-2023
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2018-2022
Maltepe University
2008-2017
Istanbul University
2003-2009
Abstract Objective To investigate the effect of infliximab on frequency uveitis attacks and visual prognosis in male patients with Behçet's disease whom was resistant to combination therapy corticosteroids, azathioprine, cyclosporine. Methods The study group comprised who were receiving but experienced at least 2 posterior uveitis/panuveitis or retinal vasculitis during 6‐month period prior enrollment. Infliximab infusions (5 mg/kg) administered weeks 0, 2, 6, 14. Weeks 0–22 defined as...
Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients with psoriasis or PsA have family history PsA, which may affect disease features. The aim this study was to assess the effects and on phenotypes.Data from 1,393 recruited in longitudinal, multicenter Arthritis International Database were analyzed. and/or characteristics investigated using logistic regression.A total 444 (31.9%) had PsA. These more frequently women, earlier onset psoriasis, frequent nail...
Objective. The aim was to assess the characteristics of PsA, find out how well disease is controlled in real life, demonstrate treatments and identify unmet needs. Methods. PsA registry Turkey a multicentre Web-based established 2014 including 32 rheumatology centres. Detailed data regarding demographics for skin joint disease, activity assessments treatment choices were collected. Results. One thousand eighty-one patients (64.7% women) with mean (s.d.) duration 5.8 (6.7) years enrolled....
AS and PsA share clinical immunological features centred on enthesitis. However, a strong association between preceding injury has been recognized. The aim of this study was to test the hypothesis that entheseal damage seen by US is commoner in patients than patients.Seventy-nine 85 had scans 1640 entheses calculate inflammation (hypoechogenicity, thickening Doppler) scores (calcifications, enthesophytes erosions). Regression modelling done evaluate effect diagnoses outcomes, controlling for...
The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients controls were investigated a sample Turkish population. B27 subtyping was performed by PCR-SSP method two groups: 49 unrelated positive with diagnosis SpA according to European Spondyloarthropathy Study Group Criteria, 55 healthy controls. HLA-B*27 2.6% population, B*2705 predominant allele among SpA. difference mainly between male proportion B27-positive significantly different (P=0.02). Our study...
Objective. To investigate the relationship between physical examination (PE) and sonographic features of enthesitis, based on anatomical sites. Methods. The analysis was done using merged raw data 3 studies 2298 entheses. Results. Patients with clinical Achilles enthesitis had more abnormalities ultrasound (US): hypoechogenicity, p < 0.001; thickening, = Doppler signals, 0.002; erosions, 0.02. patellar tendon origin also correlated PE but distal insertion plantar aponeurosis were...
Conventional radiography is key to assessing AS-related spinal involvement and has become increasingly important given that fusion may continue under biologic therapy. We aimed compare the reliability of radiographic scoring spine by using different approaches understand how readers agree on overall scores individual findings. Six investigators scored 68 plain radiographs cervical lumbar 34 patients with a 2-year interval, for erosions, sclerosis, squaring, syndesmophytes ankyloses...
Psoriasis and psoriatic arthritis (PsA) have been linked to metabolic syndrome (MS). The impact of adipokines on psoriasis, PsA, MS pathogenesis has recently received investigative attention. A total 80 subjects with 40 60 healthy controls were enrolled. Serum omentin visfatin levels measured, presence was determined. PASI DAS28 used measure disease severity for psoriasis respectively. prevalence determined be 49% in 48% 28% control groups. Rates similar PsA groups significantly greater when...
This study aims to evaluate subclinical atherosclerosis using the Ankle-Brachial Index (ABI) in patients with psoriatic arthritis (PsA).This case-control included 51 PsA (24 males, 27 females; median age 47; range, 41 52 years) recruited at our hospital's outpatient clinics between October 2016 and January 2017 50 healthy controls 26 age: 48.5; 40.7 56 years). Anthropomorphic measurements laboratory results were recorded. In patients, 66 swollen/68 tender joints count, dactylitis score,...
<h3>Background</h3> Antimalarials have been reported to worsen preexisting psoriasis, therefore is commonly avoided by the clinicians in treatment of psoriatic arthritis (PsA). With lack any solid evidence, this precludes potential use hydroxychloroquine (HQ) as a part treatment. <h3>Objectives</h3> We aimed analyze PsA patients who are treated with HQ, identify time on drug and reasons discontinuation HQ. <h3>Methods</h3> PsART (Psoriatic Arthritis Registry Turkey) prospective, multicentre,...