A5102880041- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Ocular Diseases and Behçet’s Syndrome
- Otitis Media and Relapsing Polychondritis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Systemic Sclerosis and Related Diseases
- Chronic Lymphocytic Leukemia Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Urticaria and Related Conditions
- Lymphoma Diagnosis and Treatment
- Inflammasome and immune disorders
- Vitamin D Research Studies
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Salivary Gland Disorders and Functions
- Retinal and Optic Conditions
- Inflammatory Myopathies and Dermatomyositis
- Renal Diseases and Glomerulopathies
- Sarcoidosis and Beryllium Toxicity Research
- Inflammation biomarkers and pathways
- Cervical and Thoracic Myelopathy
Istanbul Medipol University
2018-2024
Istanbul University
2016-2024
Hacettepe University
2013-2021
Marmara University
2012-2021
Ege University
2013-2019
Kahramanmaraş Sütçü İmam University
2019
Hacettepe University Hospital
2019
Süleyman Demirel University
2019
Center for Rheumatology
2012-2018
Cukurova University
2013-2016
Objective. Screening strategies for latent tuberculosis (TB) before starting tumor necrosis factor (TNF)-α inhibitors have decreased the prevalence of TB among patients who are treated with these agents. However, despite vigilant screening, continues to be an important problem, especially in parts world a high background prevalence. The aim this study was determine factors related large multicenter cohort were anti-TNF. Methods. Fifteen rheumatology centers participated study. Among 10,434...
Abstract Objectives Fatigue is a common symptom of chronic inflammatory diseases. The objective this study was to investigate fatigue in patients with Behçet's syndrome ( BS ) and examine the relationship between disease activity, quality life, anxiety depression. Methods This cross‐sectional 123 71 healthy controls Turkey. All subjects completed Multidimensional Assessment MAF questionnaire, Short form‐36 SF ‐36), Hospital Anxiety Depression HADS scale Health Questionnaire HAQ ). Disease...
Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients with psoriasis or PsA have family history PsA, which may affect disease features. The aim this study was to assess the effects and on phenotypes.Data from 1,393 recruited in longitudinal, multicenter Arthritis International Database were analyzed. and/or characteristics investigated using logistic regression.A total 444 (31.9%) had PsA. These more frequently women, earlier onset psoriasis, frequent nail...
Objective. Patient-reported outcomes (PROs) are increasingly accepted to be among the major tools for outcome assessment in rheumatic disorders. In this study we aimed assess quality of life (QoL), disability, anxiety and depression patients with Takayasu's arteritis (TAK).
Objective. To investigate the effect of depression, anxiety, fatigue, and fibromyalgia (FM) on remission status in patients with rheumatoid arthritis (RA), defined according to 28-joint count Disease Activity Score (DAS28)-erythrocyte sedimentation rate (ESR) Boolean-based new American College Rheumatology/European League Against Rheumatism criteria. Methods. The subjects were RA who participated a hospital-based observational cohort. Patients met DAS28-ESR criteria at their latest visit...
Objective. The aim was to assess the characteristics of PsA, find out how well disease is controlled in real life, demonstrate treatments and identify unmet needs. Methods. PsA registry Turkey a multicentre Web-based established 2014 including 32 rheumatology centres. Detailed data regarding demographics for skin joint disease, activity assessments treatment choices were collected. Results. One thousand eighty-one patients (64.7% women) with mean (s.d.) duration 5.8 (6.7) years enrolled....
Objective. To assess the performance of new 2012 provisional European League Against Rheumatism (EULAR)/American College Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with previous 5 diagnostic a multicenter prospective study. Methods. Patients older than 50 years, presenting new-onset bilateral shoulder pain elevated acute-phase reactants (APR), were assessed for fulfillment and old...
Periodontitis is a suspected environmental risk factor for the development of rheumatoid arthritis (RA). However, correlation mechanisms between two pathologies remain elusive. This study examined potential correlations detached subgingival bacteria collected in gingival crevicular fluid (GCF) and RA parameters.RA patients (n = 52, F:M 40:12), with Behcet's disease (BD, n 40, 29:11) as another systemic inflammatory were studied along systemically healthy control group (HC, 57, 40:17). All...
Abstract The triggering receptor expressed on myeloid cells 1 (TREM-1) and peptidoglycan recognition protein (PGLYRP1) are involved in the propagation of inflammatory responses. This study investigated whether serum levels TREM-1 PGLYRP1 correlate with periodontitis rheumatoid arthritis (RA) patients. A total 154 non-smoking participants RA (n = 55, F/M: 41/14), Behçet´s disease (BD, n 41, 30/11) healthy controls (HC, 58, 40/18) were recruited. Serum saliva collected, 28-joint activity score...
To assess the effect of mycophenolate mofetil (MMF) on pulmonary functions in patients with systemic sclerosis-associated lung disease (SSc-ILD) who experienced an inadequate response to first line cyclophosphamide (CYC) therapy. Twelve consecutive SSc-ILD received MMF due CYC as a agent, were retrospectively reviewed. Over course 2 years, function tests (PFT) and high-resolution computed tomography (HRCT) scans performed. Following initial baseline tests, PFTs continued at frequency every 6...
To retrospectively analyze disease activity and damage-associated factors in granulomatosis with polyangiitis (GPA) Turkey.A retrospective analysis was carried out 21 GPA patients. Assessments for were performed the Birmingham Vasculitis Activity Score (BVAS/GPA) permanent organ damage by Damage Index (VDI).Lower BVAS/GPA (P = 0.002), absence of renal involvement 0.003) higher creatinine clearence 0.000) at diagnosis increased likelihood achieving remission 6 weeks. Relapses associated high...
Objective Data regarding the frequency of fibromyalgia (FM) in patients with Takayasu's arteritis (TAK) have not been previously reported. We aimed to investigate FM TAK, defined according new 2010 ACR Preliminary Diagnostic Criteria for Fibromyalgia. The association between ACR-1990 and criteria effects patient-reported outcomes (PROs) on were also analyzed. Methods studied 55 (age: 42,30±12,37 years, F/M: 49/6) TAK 40 age- sex-matched controls 41±10.84 31/9). All examined tender points by...
Systemic sclerosis (SSc) is a connective-tissue disorder characterized by microvascular damage and tissue fibrosis. Although overt nervous system involvement unusual in SSc, imaging studies have shown cerebral hypoperfusion. We evaluated cognitive functions patients with SSc who had no history of neurological involvement, to seek impairment caused the suggested hypoperfusion.We performed comprehensive neuropsychological test battery on 31 2 groups age-adjusted, sex-adjusted,...
The effect of disease-modifying antirheumatic drugs (DMARDs) in ankylosing spondylitis (AS) is still controversial. We aimed to evaluate the efficacy sulphasalazine (SSZ) mono- or combination therapy with methotrexate (MTX) AS patients naive anti-tumor necrosis factor alpha (TNFα) agents.Patients (n = 87, male : female, 46 41) treated SSZ 61) + MTX 26) and a documented 6-month follow-up were evaluated retrospectively. Disease activity was assessed by Bath Ankylosing Spondylitis Activity...