A5034080180- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Vasculitis and related conditions
- Inflammasome and immune disorders
- Systemic Sclerosis and Related Diseases
- Ocular Diseases and Behçet’s Syndrome
- Atherosclerosis and Cardiovascular Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Psoriasis: Treatment and Pathogenesis
- Biosimilars and Bioanalytical Methods
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Chronic Lymphocytic Leukemia Research
- Tuberculosis Research and Epidemiology
- Renal Diseases and Glomerulopathies
- Otitis Media and Relapsing Polychondritis
- Musculoskeletal synovial abnormalities and treatments
- Infectious Diseases and Tuberculosis
- Hepatitis C virus research
- Retinal and Optic Conditions
- Bone and Joint Diseases
- Platelet Disorders and Treatments
- Pulmonary Hypertension Research and Treatments
- Hepatitis B Virus Studies
Hacettepe University
2016-2025
Center for Rheumatology
1996-2023
Hippocration General Hospital
2023
Ankara University
2023
Tokyo Metropolitan Tama Medical Center
2023
National and Kapodistrian University of Athens
2023
Faculty (United Kingdom)
2020-2021
Hacettepe University Hospital
1997-2015
Turkish Thoracic Society
2014
Cukurova University
2008-2013
Validation of a translated, culturally adapted questionnaire.To translate and adapt the Turkish version Oswestry Disability Index (ODI) (2.0), to validate its use for assessing disability in patients with low back pain.The ODI is reliable evaluation instrument disability, but no validated available.A total 95 outpatients pain were assessed by ODI. Sixty-five these observed on second occasion. Translation/retranslation ENG was done blindly independently four different individuals, team....
Abstract Objective Scleroderma (SSc) is an autoimmune disease of unknown etiology. The 3–8 times more frequent in women than men. role X chromosome inactivation (XCI) the predisposition to autoimmunity has been questioned. Until now this not illustrated experimentally. This study was undertaken test hypothesis that disturbances XCI mosaicism may be involved pathogenesis female patients with SSc. Methods Seventy SSc and 160 controls were analyzed for androgen receptor locus by Hpa...
Objective Takayasu arteritis is a rare large vessel vasculitis with incompletely understood etiology. This study was undertaken to perform the first unbiased genome‐wide association analysis of arteritis. Methods Two independent cohorts patients from Turkey and North America were included in our study. The Turkish cohort consisted 559 489 controls, American 134 1,047 controls European ancestry. Genotyping performed using Omni1‐Quad Omni2.5 genotyping arrays. data subjected rigorous quality...
To investigate the effectiveness and acceptability, thus practicability of a biopsychosocial-based exercise model in rheumatic diseases by mixed method. This study is within framework mixed-method research that combines strengths quantitative qualitative methodologies. For part study, 81 patients were divided into two groups Bilişsel Egzersiz Terapi Yaklaşımı (BETY)- (Cognitive Exercise Therapy Approach English) group (BETY Group-BG) control (CG). BG participants engaged supervised sessions...
Recent studies point out a probable role of streptococcal antigens in the pathogenesis Behçet's disease (BD). This has led to proposal benzathine penicillin as therapeutic modality BD.A prospective study was conducted compare efficacy colchicine and + treatments on mucocutaneous manifestations BD.60 patients (group I) were given alone 94 II) penicillin. Frequency, number, duration severity oral aphthous ulcers, genital ulcers erythema nodosum determined before after treatment.In group I, all...
Objective. Disease Extent Index-Takayasu (DEI.Tak) is a new index developed for the follow-up of Takayasu's arteritis (TA), assessing only clinical findings without requirement imaging. We investigated effectiveness DEI.Tak in disease activity and progression by comparing with physician's global assessment (PGA) active criteria defined Kerr et al.
HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they associated different vasculitides (HLA-B*51 in Behçet's disease Takayasu's arteritis (TAK)) major clinical immunological In this study, we aimed to screen a large cohort of TAK patients from Turkey for the presence as susceptibility severity factors.TAK (n = 330) followed at total 15 centers were included study. The mean age was 37.8 years, 86% women. DNA samples...
Abstract Objective . Because exposure to streptococcal antigens might be a major disease activity—provoking factor in Behçet's disease, this study was undertaken evaluate the effectiveness of benzathine penicillin prophylaxis recurrent arthritis episodes during course disease. Methods A prospective, randomized design used allocate patients receive colchicine alone or plus for 24 months. Results The duration, severity, and pattern were found similar 2 treatment groups, but number...
Background: Effectiveness of anti-tumor necrosis factor (anti-TNF) agents in colchicine-resistant familial Mediterranean fever (FMF) patients has attracted attention recent years. Objective: We analyzed the effect anti-TNF on clinical findings FMF with chronic arthritis and/or sacroiliitis. Methods: Data from 10 (5 male and 5 female patients: mean age, 30.1 [SD, 8.5] years) sacroiliitis who were are reviewed. Frequency attacks before after treatment was recorded hospital files. The effects...
Objective. Patient-reported outcomes (PROs) are increasingly accepted to be among the major tools for outcome assessment in rheumatic disorders. In this study we aimed assess quality of life (QoL), disability, anxiety and depression patients with Takayasu's arteritis (TAK).
Reactive haemophagocytic syndrome (RHS) is a hyperinflammatory disorder often occurring in the background of several disorders such as infections, malignancies, and rheumatic diseases. Recently, score known HScore was developed for diagnosis RHS. In original study, most patients had underlying haematological malignancy or infection best cut-off value 169 (sensitivity 93%; specificity 86%). this study we aimed to analyse performance disease-related RHS.The with evaluated Departments...