A5032970295- Inflammasome and immune disorders
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Vasculitis and related conditions
- Retinal and Optic Conditions
- interferon and immune responses
- Otitis Media and Relapsing Polychondritis
- Urticaria and Related Conditions
- Gout, Hyperuricemia, Uric Acid
- IL-33, ST2, and ILC Pathways
- Psoriasis: Treatment and Pathogenesis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Kawasaki Disease and Coronary Complications
- Renal Diseases and Glomerulopathies
- Hepatitis C virus research
- Biosimilars and Bioanalytical Methods
- Hepatitis B Virus Studies
- Systemic Sclerosis and Related Diseases
- Eosinophilic Disorders and Syndromes
- Inflammatory Myopathies and Dermatomyositis
- Cerebral Venous Sinus Thrombosis
Gazi University
2014-2024
Eskişehir Osmangazi University
2015-2024
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2017-2022
Hacettepe University
2013-2021
Center for Rheumatology
2007-2021
Eskişehir City Hospital
2018-2020
Cukurova University
2013-2015
Ege University
2013-2015
Marmara University
2013-2015
Gaziantep University
2013-2015
Vascular involvement is one of the major causes mortality and morbidity in Behçet disease (BD). There are no controlled studies for management vascular BD (VBD), according to EULAR recommendations, only immunosuppressive (IS) agents recommended. In this study, we aimed investigate therapeutic approaches chosen by Turkish physicians during initial event relapses VBD association different treatment options with retrospectively. Patients (n = 936, female/male: 347/589, mean age: 37.6 ± 10.8)...
The primary aim of this study was to investigate the prevalence amyloidosis and its related factors in a large number FMF patients.Fifteen centres from different geographical regions Turkey were included study. Detailed demographic medical data based on structured questionnaire records collected. diagnosis histological proof congophilic fibrillar deposits tissue biopsy specimens.There 2246 patients. male/female ratio 0.87 (1049/1197). mean age patients 34.5 years (S.D. 11.9). Peritonitis...
Colchicine is the main treatment for familial Mediterranean fever (FMF). However, biological agents and other treatments are available patients who unable to receive optimal treatment.To develop outcome criteria that define response treatment.Two rounds of Delphi exercise were followed by a consensus conference enabling definition be employed. Data with FMF responding resistant their obtained from Arthritis Vasculitis Orphan disease Research in paediatric rheumatology (FAVOR) website. The...
Objective. Patient-reported outcomes (PROs) are increasingly accepted to be among the major tools for outcome assessment in rheumatic disorders. In this study we aimed assess quality of life (QoL), disability, anxiety and depression patients with Takayasu's arteritis (TAK).
Approximately 30-45% of patients with familial Mediterranean fever (FMF) have been reported to attacks despite colchicine treatment. Currently, data on the treatment colchicine-unresponsive or colchicine-intolerant FMF are limited; most promising alternatives seem be anti-interleukin-1 (anti-IL-1) agents. Here we report our experience off-label use anti-IL-1 agents in a large group patients.In all, 21 centers from different geographical regions Turkey were included current study. The medical...
To assess bladder toxicity of cyclophosphamide (CYC) and uroprotective effect mesna in rheumatic diseases.Data 1018 patients (725 women/293 men) treated with CYC were evaluated this retrospective study. All the following information was obtained: cumulative dose, route administration, duration therapy, concomitant usage, hemorrhagic cystitis. Cox proportional hazard model used for statistics.We identified 17 (1.67%) cystitis 2 (0.19%) cancer 4224 patient-years. The median time diagnosis to...
Abstract Objectives Paraneoplastic arthritis ( PA ) may mimic rheumatic diseases. While presenting the demographic and laboratory features of patients diagnosed with , this study also aims to provide possible appropriate tools differentiate cases from early rheumatoid ERA ). Methods Sixty‐five (male/female: 43/22) 15 different rheumatology clinics 50 consecutive 13/37) fulfilling 2010 American College Rheumatology ACR criteria for diagnosis if RA Gaziantep Early Arthritis Trial GREAT as...
Objective: Previous studies have reported that cardiovascular involvement in rheumatoid arthritis (RA) occurs frequently. Although ventricular functions of RA been investigated through the standard Doppler RA, they yet to be thoroughly by means relatively new and advantageous tissue imaging (TDI). The present study aims investigate left right patients TDI echocardiography. Methods: A total 60 with longstanding 40 control subjects were included their assessed pulsed‐wave echocardiography,...
Abstract Aim Familial Mediterranean fever ( FMF ) is the most common autoinflammatory disease. One of characteristics this disease its young age predominance. Nearly 90% patients experience flares during early adult periods. Currently there are limited data for comparison versus late onset and therefore primary aim study was to investigate these two subsets with regard their certain demographic, clinical genetic differences. Methods Early (≤ 20 years, Group 1) (> 2) were identified from...
Persistent inflammation is an insidious and less studied feature of FMF. We investigated clinical determinants persistent its associations with individual damage items.This a cross-sectional analysis 917 FMF patients, who fulfilled the Tel Hashomer criteria had at least 6 months' follow-up. Patients were stratified based on whether they inflammation. used logistic regression to investigate independent predictors associated items.One hundred forty-two (15%) patients Active (54%) was most...
Familial Mediterranean fever (FMF) is characterized by recurrent episodes of peritonitis. Abdominal FMF attacks can be indistinguishable from those an acute abdominal emergency, and patients may undergo one or more laparotomies before the true nature their disease documented. The objectives this study were to investigate frequency reasons for surgeries performed on with FMF.We retrospectively reviewed files 254 (127 males, 127 females, mean age 27.2+/-6.3 years). We also included 182 healthy...