Nazife Şule Yaşar Bilge

ORCID: 0000-0002-0783-1072
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About
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Research Areas
  • Vasculitis and related conditions
  • Ocular Diseases and Behçet’s Syndrome
  • Inflammasome and immune disorders
  • Rheumatoid Arthritis Research and Therapies
  • Systemic Lupus Erythematosus Research
  • Spondyloarthritis Studies and Treatments
  • Retinal and Optic Conditions
  • Urticaria and Related Conditions
  • Autoimmune and Inflammatory Disorders Research
  • Otitis Media and Relapsing Polychondritis
  • Sarcoidosis and Beryllium Toxicity Research
  • Systemic Sclerosis and Related Diseases
  • Biosimilars and Bioanalytical Methods
  • Kawasaki Disease and Coronary Complications
  • interferon and immune responses
  • Renal Diseases and Glomerulopathies
  • Bone and Joint Diseases
  • Autoimmune and Inflammatory Disorders
  • Gout, Hyperuricemia, Uric Acid
  • Cerebral Venous Sinus Thrombosis
  • IL-33, ST2, and ILC Pathways
  • Cholesterol and Lipid Metabolism
  • Hepatitis C virus research
  • Liver Diseases and Immunity
  • Atherosclerosis and Cardiovascular Diseases

Eskişehir Osmangazi University
2014-2024

Psychiatric Association of Turkey
2024

Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2016-2022

Center for Rheumatology
2021

Eskişehir City Hospital
2014-2020

Adli Tıp Kurumu
2016

State Hospital
2014

Wake Forest University
1963

Atrium Health Wake Forest Baptist
1963

Objectives: This study aimed to examine the frequency and associated factors of extra-musculoskeletal manifestations (EMMs) peripheral in an axial spondyloarthritis (axSpA) cohort their impact on choice first biologic treatment. Patients methods: A total 1,687 patients with axSpA (978 males, 709 females; mean age: 38.5±11 years) who started disease modifying antirheumatic drug (bDMARD) were included from a national prospective database TReasure between its inception 2018-2021. Demographic...

10.46497/archrheumatol.2025.10670 article EN Archives of Rheumatology 2025-03-01

Abstract Aim Familial Mediterranean fever ( FMF ) is the most common autoinflammatory disease. One of characteristics this disease its young age predominance. Nearly 90% patients experience flares during early adult periods. Currently there are limited data for comparison versus late onset and therefore primary aim study was to investigate these two subsets with regard their certain demographic, clinical genetic differences. Methods Early (≤ 20 years, Group 1) (> 2) were identified from...

10.1111/1756-185x.13259 article EN International Journal of Rheumatic Diseases 2018-01-05

The distribution of Mediterranean fever (MEFV) gene mutations in Turkish familial (FMF) patients varies according to geographic area Turkey. There is a need for highly representative data FMF patients. aim our study was investigate the common MEFV nationwide, multicenter study.Data 2246 patients, from 15 adult rheumatology clinics located different parts country, were evaluated retrospectively. following have been tested all patients: M694V, M680I, M694I, V726A, and E148Q.There 1719 with...

10.3906/sag-1809-100 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2019-01-17

Persistent inflammation is an insidious and less studied feature of FMF. We investigated clinical determinants persistent its associations with individual damage items.This a cross-sectional analysis 917 FMF patients, who fulfilled the Tel Hashomer criteria had at least 6 months' follow-up. Patients were stratified based on whether they inflammation. used logistic regression to investigate independent predictors associated items.One hundred forty-two (15%) patients Active (54%) was most...

10.1093/rheumatology/keaa378 article EN Lara D. Veeken 2020-06-03

Background/aim: Colchicine is the mainstay of treatment in FMF. However, daily practice it not easy to maintain effective colchicine doses a substantial number patients due its side effects. In this study, we aimed investigate prevalence and risk factors for effects that limit optimal drug dosing cause permanent discontinuation. Materials methods: All were recruited from "FMF Central Anatolia" (FiCA) cohort, 915 adults with minimum follow-up time 6 months during which they had obeyed all...

10.3906/sag-2001-261 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2020-05-05

Objective: This study aimed to investigate the frequency in which familial Mediterranean fever (FMF) coexists with other diseases and determine whether (MEFV) gene mutations are involved such coexistence.Material Methods: In total, 142 consecutive patients FMF investigated for MEFV mutation were enrolled this [Female: 87; Male: 55,].All questioned presence of concurrent disorders, medical records these revised retrospectively.A previous diagnosis inflammatory disorder than was considered...

10.5152/eurjrheum.2016.16012 article EN cc-by-nc European Journal of Rheumatology 2016-09-26

Cerebral mass-like lesion (MLL) is a rare form of Neuro-Behçet' s (NB) disease.There currently no detailed knowledge on this issue in the literature.Our aim was to describe Behçet' disease (BD) patient with MLL, followed by clinical analysis light available literature regarding BD patients who suffered from an MLL or tumefactive brain.We conducted review English analyse data BD.The Pub-Med, Web Science, Proquest and Ovid databases were searched for articles abstracts using term "Behçet'...

10.5152/eurjrheum.2014.007 article EN cc-by-nc European Journal of Rheumatology 2014-03-07

<title>Abstract</title> <bold>Aim:</bold>To investigate cancer incidence in patients with ANCA-associated vasculitides (AAV), compare it the age/sex-spesific risk of Turkish population, explore independent factors associated cancer. <bold>Methods:</bold>This multicenter, case-control study was conducted using TRVaS registry. AAV without history before diagnosis were included. Demographic and AAV-related data an incident compared. Standardized rates calculated 2017 National Cancer Registry...

10.21203/rs.3.rs-3860558/v1 preprint EN cc-by Research Square (Research Square) 2024-01-23

Abstract To investigate cancer incidence in patients with ANCA-associated vasculitis (AAV), compare it the age/sex-specific risk of Turkish population, and explore independent factors associated cancer. This multicenter, case–control study was conducted using TRVaS registry. AAV without history before diagnosis were included. Demographic AAV-related data an incident compared. Standardized rates calculated age-/sex-specific 2017 National Cancer Registry for cancers (excluding non-melanoma...

10.1007/s11739-024-03577-9 article EN cc-by Internal and Emergency Medicine 2024-03-29

Background/aim: The TReasure registry, created in 2017, is an observational multicenter cohort that includes inflammatory arthritis patients. This article reviews the methodology and objectives of registry established to collect data from rheumatoid (RA) spondyloarthritis (SpA) Methodology: Fifteen rheumatology centers Turkey will contribute database. actual proprietor database Hacettepe Rheumatology Association (HRD) Financial Enterprises. Pharmaceutical companies operate (in alphabetical...

10.3906/sag-1807-200 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2018-08-16
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