A5017671399- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Otitis Media and Relapsing Polychondritis
- Ocular Diseases and Behçet’s Syndrome
- IgG4-Related and Inflammatory Diseases
- Biosimilars and Bioanalytical Methods
- Systemic Sclerosis and Related Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Psoriasis: Treatment and Pathogenesis
- Kawasaki Disease and Coronary Complications
- Renal Diseases and Glomerulopathies
- Retinal and Optic Conditions
- Eosinophilic Disorders and Syndromes
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Inflammasome and immune disorders
- Microscopic Colitis
- Inflammatory Bowel Disease
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Heart Failure Treatment and Management
- Autoimmune and Inflammatory Disorders
Gazi University
2024-2025
Hacettepe University
2016-2024
Psychiatric Association of Turkey
2024
Sivas State Hospital
2023
Hippocration General Hospital
2023
Ankara University
2023
Tokyo Metropolitan Tama Medical Center
2023
Center for Rheumatology
2023
National and Kapodistrian University of Athens
2023
National Institutes of Health
2021-2022
Targeted therapies have been associated with potential risk of malignancy, which is a common concern in daily rheumatology practice patients inflammatory arthritis (IA) and history cancer. To perform systematic literature review to inform Task Force formulating EULAR points consider on the initiation targeted IA Specific research questions were defined within before exact queries librarian. We included studies reporting relative measure cancer initiating therapy or conventional synthetic...
Objective We describe the demographics, clinical features, disease course, and survival of polyarteritis nodosa (PAN) through an international collaboration (GLOBAL‐PAN). Methods Patients with PAN were recruited between 1990 2020 from observational cohorts nine countries across Europe, Japan, North America. Eligibility was retrospectively defined using European Medicines Agency classification algorithm. related to hepatitis B virus (n = 12) two monogenic diseases mimicking PAN, deficiency...
Potential associations between targeted therapies and a new cancer in patients with inflammatory arthritis (IA) previous malignancy are frequent concern daily rheumatology practice. To develop points to consider (PTC) assist rheumatologists when initiating therapy the context of malignancy. Following EULAR standardised operating procedures, task force met define research questions for systematic literature review formulate overarching principles (OPs) PTC. The group formulated five OPs;...
To describe a rare case of recurrent anterior nodular scleritis as the initial manifestation paraneoplastic syndrome in patient with colorectal cancer. A report 47-year-old female history acute lymphoblastic leukemia who presented ocular pain, redness, and blurred vision her right eye. Despite treatment corticosteroids methotrexate, experienced monthly recurrences scleritis. comprehensive work-up was conducted to investigate underlying systemic disease. Laboratory investigations revealed...
Abstract Background Antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) and immunoglobulin G4‐related disease (IgG4‐RD) have some common features. The co‐occurrence/concurrence of AAV IgG4‐RD was recently published by the collaborative European Vasculitis Study Group. First, we aimed to investigate ANCA positivity our cohort. Second, a literature review done. Methods Data 62 patients with in Hacettepe Center Database were used. Patient dataset designed include demographic...
The course of novel coronavirus disease 2019 (COVID-19) has been special concern in patients with inflammatory rheumatic diseases (IRDs) due to the immune dysregulation that may be associated these and medications used for IRDs, affect innate responses.In this cohort study, we aimed report characteristics variables COVID-19 outcome among Turkish IRDs.Between April June, 2020, 167 adult IRD were registered from 31 centers 14 cities Turkey. Disease was classified 4 categories; (i) outpatient...
Background/aim: To assess the real-life efficacy, retention rate, and safety data of tofacitinib in rheumatoid arthritis (RA) patients. Materials methods: We analyzed all patients registered HURBİO database who received at least 1 dose tofacitinib. Patients one were included analysis; with control visit efficacy analysis. Factors predicting good response last follow-up by logistic regression Drug rates calculated using Kaplan-Meier method predictors drug determined Cox proportional hazard...
To assess whether data from 18F-fluorodeoxyglucose (FDG) PET should be incorporated into eligibility criteria for clinical trials in Takayasu's arteritis (TAK).The study was conducted two parts. Part one an international online survey among physicians with experience managing TAK to determine, using vignettes, FDG-PET influence decisions about enrolment trials. used patient observational cohort agreement regarding trials, based on assessment and without incorporation of data.In part one, 68...
OBJECTIVE: This study aimed to investigate Behçet’s syndrome (BS) patients’ regarding anthropometric measurements, daily energy and nutrient intake, the MD adherence of patients. METHODS: 100 consecutive patients with BS were prospectively enrolled in two rheumatology outpatient clinics. Mid Upper Arm circumference (MUAC), Triceps skinfold thickness (TST), Muscle Circumference (MUAMC), Area (MUAMA) measurements compared Turkish reference values. Participants’ intake categorized by ‘MD...
Colistin and carbapenem-resistant Acinetobacter calcoaceticus- baumannii complex (CCR-Acb complex) was isolated from two consecutive patients in the neurological intensive care unit (NICU). An urgent reaction to this desperate situation required.Screening cultures were taken other sharing NICU with index repeated periodically. closed for new admissions. Infection control precautions (ICP) such as hand hygiene, cohorting colonized CCR-Acb complex, staff caring these patients, daily bathing...
<h3>Background</h3> Imaging recommendations for primary large vessel vasculitis (LVV) were developed in 2018. Several new studies have emerged since then, and an update of the original statements was required. <h3>Objectives</h3> To use imaging LVV. <h3>Methods</h3> A systematic literature review performed to retrieve evidence on ultrasound (US), magnetic resonance (MRI), computed tomography (CT) [18F]-fluorodeoxyglucose positron emission (FDG-PET) diagnosis, monitoring outcome prediction...
To explore the frequency and clinical associations of radiologic pleuroparenchymal fibroelastosis (PPFE) in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).In this single-center retrospective study, high resolution computed tomography (HRCT) images 105 SSc-ILD were examined for presence PPFE. Demographic, clinical, laboratory, pulmonary function test (PFT) data without PPFE compared.PPFE was detected 19 (18.1%) ('definite PPFE' 13 'consistent 6 patients)....
<h3>Background</h3> Potential associations between targeted therapies in patients with an inflammatory arthritis (IA) and malignancy are a frequent concern daily rheumatology practice. No specific framework has been proposed to evaluate the benefit/risk balance of initiating or reinitiating therapy (bDMARDs/tsDMARDs) IA history cancer. <h3>Objectives</h3> To perform systematic literature review (SLR) inform task force formulating. EULAR Points Consider on initiation patients....
Many etiologies are held accountable for nasal septum perforations. Topical drug usage, previous surgeries, trauma, nose picking, squamous cell carcinoma, some rheumatological disorders such as granulomatosis with polyangiitis (Wegener granulomatosis), infectious diseases syphilis and leprosy among the causes of Occupational heavy metal exposures by inhalation rarely may also cause perforation. Here, we present a 29-year-old patient without any known diseases, who is worker at metallic...
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory which affects many systems, as well the cardiovascular system. Identifying coronary involvement like periaortitis, periarteritis and pericarditis important, they often cause unfavorable outcomes.Eighty-one patients with IgG4-RD were retrospectively evaluated for symptomatic artery from Hacettepe University Vasculitis Research Center (HUVAC) database. The demographic, laboratory, radiologic clinical...
<h3>Background</h3> Potential associations between targeted therapies and a new cancer in patients with an inflammatory arthritis (IA) history of malignant disease are frequent concern daily rheumatology practice. IA and/or immunomodulatory drugs might confer specific risk malignancy. No evidence-based framework has been proposed to guide clinicians on the benefit/risk balance when initiating or reinitiating therapy (bDMARDs/tsDMARDs) this context. <h3>Objectives</h3> This initiative aimed...
Background/aim: Since the majority of IgG4-related disease (IgG4-RD) patients in literature are from Far East and United States, there is a lack large series other parts world. We aimed to identify clinical characteristics outcome Turkish IgG4-RD tertiary center.Materials methods: Fifty-two classified as having definite according comprehensive diagnostic criteria were included study. Patients not fulfilling due pathologic specimen and/or serum IgG4 levels excluded (n = 47). Clinical,...