A5080875771- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Bone and Joint Diseases
- Ocular Diseases and Behçet’s Syndrome
- COVID-19 Clinical Research Studies
- Gout, Hyperuricemia, Uric Acid
- Blood Coagulation and Thrombosis Mechanisms
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Biosimilars and Bioanalytical Methods
- Salivary Gland Disorders and Functions
- Infectious Diseases and Tuberculosis
- Systemic Sclerosis and Related Diseases
- Otitis Media and Relapsing Polychondritis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Immune Cell Function and Interaction
- Spine and Intervertebral Disc Pathology
- interferon and immune responses
- Bone health and osteoporosis research
- Medical Imaging and Analysis
- Tuberculosis Research and Epidemiology
- Sarcoidosis and Beryllium Toxicity Research
Sakarya University
2018-2024
Korean Council for University Education
2024
Eskişehir City Hospital
2014-2022
Sakarya Eğitim ve Araştırma Hastanesi
2022
Hacettepe University
2013-2021
Center for Rheumatology
2013-2021
Eskişehir Osmangazi University
2012-2019
Türk Anesteziyoloji ve Reanimasyon Derneği
2017
State Hospital
2016
Kocaeli Üniversitesi
2006-2014
The primary aim of this study was to investigate the prevalence amyloidosis and its related factors in a large number FMF patients.Fifteen centres from different geographical regions Turkey were included study. Detailed demographic medical data based on structured questionnaire records collected. diagnosis histological proof congophilic fibrillar deposits tissue biopsy specimens.There 2246 patients. male/female ratio 0.87 (1049/1197). mean age patients 34.5 years (S.D. 11.9). Peritonitis...
Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients with psoriasis or PsA have family history PsA, which may affect disease features. The aim this study was to assess the effects and on phenotypes.Data from 1,393 recruited in longitudinal, multicenter Arthritis International Database were analyzed. and/or characteristics investigated using logistic regression.A total 444 (31.9%) had PsA. These more frequently women, earlier onset psoriasis, frequent nail...
Abstract Aim Familial Mediterranean fever ( FMF ) is the most common autoinflammatory disease. One of characteristics this disease its young age predominance. Nearly 90% patients experience flares during early adult periods. Currently there are limited data for comparison versus late onset and therefore primary aim study was to investigate these two subsets with regard their certain demographic, clinical genetic differences. Methods Early (≤ 20 years, Group 1) (> 2) were identified from...
The aim was to profile serum and salivary levels of active-matrix metalloproteinase (aMMP)-8, tissue inhibitor MMP (TIMP)-1, aMMP-8/TIMP-1 ratio, total (tMMP)-9, tMMP-9/TIMP-1 myeloperoxidase (MPO), human neutrophil elastase (HNE) in periodontitis rheumatoid arthritis (RA).
BACKGROUND: The aim of this study was to clarify the effects continuous passive motion (CPM) treatment on adhesive capsulitis (AC) in diabetes mellitus (DM) patients. METHODS: Forty-one DM patients with AC were randomized two groups. first group (n= 20) (CPM group) received CPM treatments; second 21) had conventional physical therapy (CPT group), including active stretching, range (ROM) and pendulum exercises. All electrotherapy. After a four-week-long program, instructed continue an...
Monocyte chemoattractant protein-1 (MCP-1), macrophage migration inhibitory factor (MIF), and fractalkine are chemokines that expressed by a variety of cell types to regulate inflammatory response. The aim the study was examine effects periodontitis rheumatoid arthritis (RA) on their serum salivary concentrations.Adults with either (P, n = 21), or (RA, 23), both diseases (RA+P, 23) were included in study. Systemically periodontally healthy individuals (n 22) served as controls. Saliva...
The objectives of this study were to assess the clinical characteristics, predictive factors, and practical algorithms paradoxical reactions (PRs), specifically psoriasis (PP).
An effective treatment strategy for Felty syndrome (FS) has not been developed so far.In this article, three cases with FS, who responded to different modalities, have presented.Case 1 was a 52-year-old male patient initially received methotrexate, and then, he switched granulocyte colony-stimulating factor (G-CSF) cyclosporine when his neutropenia further deteriorated.The needed monthly doses of G-CSF nearly 6 months, steroid dose increased.Afterwards, improved cyclosporine,...
Familial Mediterranean fever (FMF) is the most common autoinflammatory disease. Most of identified disease-causing mutations are located on exon 10. As number studies about effect exonal location mutation and its phenotypic expression limited, we aimed to investigate whether exonic (MEFV) has an clinical manifestation in patients with FMF.Study population was derived from main FMF registry that included 2246 15 different rheumatology clinics. We categorized according their locations...
Cup-like morphology is defined as cup-like nuclear invagination spanning ≥25% of the diameter in >10% blasts.Studies have shown that FLT3 ITD and normal cytology are strongly associated with acute myeloid leukemia (AML) patients.Herein we describe a patient blasts was diagnosed treated for common lymphoblastic (ALL).In contrast to literature, presented case Philadelphia chromosome positive negative.(
Abstract Aim Insulin resistance ( IR ) plays an important role in the development of cardiovascular events rheumatoid arthritis RA patients. Adiponectin influences insulin sensitivity but its impact on patients remains unclear. The present study aims to investigate methotrexate MTX and low doses prednisolone LDP adiponectin levels who are naïve disease‐modifying antirheumatic drugs DMARD s), as well determining relationship between disease activity, acute phase response, with . Methods...
To evaluate treatment adherence and predictors of drug discontinuation among patients with inflammatory arthritis receiving bDMARDs within the first 100 days after announcement COVID-19 pandemic.A total 1871 recorded in TReasure registry for whom advanced therapy was prescribed rheumatoid (RA) or spondyloarthritis (SpA) 3 months (6–9 rituximab) before declaration pandemic were evaluated, 1394 (74.5%) responded to phone survey. Patients’ data regarding demographic, clinical characteristics...
Vascular events are a common complication in patients with polycythemia vera (PV) and essential thrombocythemia (ET). This study aimed to analyze the association between PAI-1 4G/5G ACE I/D gene polymorphisms, leukocytosis thrombosis PV ET.In total, 64 ET were evaluated. Arterial or venous thrombosis, such as cerebral transient ischemic attack, stroke, myocardial infarction, peripheral arterial deep pulmonary embolism, defined vascular event. DNA samples screened for mutations via reverse...