A5090636051- Inflammatory Bowel Disease
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Microscopic Colitis
- Autoimmune and Inflammatory Disorders
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Genetic and rare skin diseases.
- Gastric Cancer Management and Outcomes
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- COVID-19 Clinical Research Studies
- Dermatological and Skeletal Disorders
- Metastasis and carcinoma case studies
- Liver Diseases and Immunity
- Chronic Myeloid Leukemia Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Diverticular Disease and Complications
- IL-33, ST2, and ILC Pathways
- Esophageal and GI Pathology
- Cancer Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Tuberculosis Research and Epidemiology
- Pregnancy and Medication Impact
Yeditepe University
2025
Bolu Abant İzzet Baysal University
2014-2022
Lokman Hekim Üniversitesi
2021
Izmir Kâtip Çelebi University
2013-2016
Hospital Universitario de La Princesa
2016
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2016
University of Palermo
2016
Creative Commons
2015
Marmara University
2007-2015
Acıbadem Adana Hospital
2015
Aim: The aim was to develop a high-performance computer-aided diagnosis (CAD) system with image processing and pattern recognition in diagnosing pancreatic cancer by using endosonography images. Materials Methods: On the images, regions of interest (ROI) three groups patients (<40, 40-60 >60) were extracted experts; features obtained from images different techniques trained separately for each age group an Artificial Neural Network (ANN) diagnose cancer. study conducted on 202 130 noncancer...
Introduction: Bipolar 2 disorder (BD2) is an independent disease with specific familial aggregation, significant functional impairment, treatment challenges and several distinctive clinical features. However, unlike bipolar 1 disorder, studies investigating causal genes are lacking. This study aims to identify prioritize genetic variants for BD2 by analyzing brain-specific gene expression markers, improve the understanding of its underpinnings support advancements in diagnosis, prognosis....
<title>Abstract</title> Hydrogels, composed of cross-linked polymer networks with high water content, are widely explored for biomedical applications due to their tunable properties and biocompatibility; however, limited mechanical strength restricts use in load-bearing or dynamic environments, a challenge that can be addressed by incorporating conductive nanoparticles enhance both resilience electrical conductivity. In this work, we unveil the formation mechanism silver nanowire (AgNW)...
Saccharomyces boulardii is a probiotic used for the prevention of antibiotic-associated diarrhoea. We aimed to investigate whether S. could alter effects clarithromycin (CLA) and methotrexate (MTX) on oro-caecal intestinal transit oxidative damage in rats. Rats were divided into two groups receiving single dose MTX (20 mg/kg) or CLA mg/kg per d) 1 week. Groups treated with either saline (500 twice d throughout experiment. The control group was administered only saline. Following...
Neutrophil-lymphocyte ratio (NLR) has been used as a simple, affordable, and easily accessible marker to predict prognosis in variety of inflammatory neoplastic diseases. However, there are few studies investigating their role patients with hepatitis B. The aim this study was investigate the relationship between NLR liver fibrosis who were being followed inactive B carriers.The included 78 for 1 year carriers. Liver biopsy performed scores histological activity index assessed according...
Background: The effect of hepatitis B virus (HBV) infection on fatty liver disease is unclear..Objectives: aim this study was to investigate the viral and host causes in chronic (CHB) patients. This included 88 CHB patients which 17 were not treated. Liver biopsy performed each patient. Group 1 those with hepatic steatosis (n=28) group 2 without steatosis. groups compared terms age, body mass index (BMI), Homeostasis Model Assessment- Insulin Resistance (HOMA-IR), load, biochemical...
Inflammatory bowel disease is a chronic inflammatory of the gastrointestinal system. In some cases, current medications used for may not be enough remission, creating need more potent and reliable medications. There no study showing efficacy fostamatinib, with proven effects on diseases, ulcerative colitis. our we planned to research spleen tyrosine kinase inhibitor, acetic acid-induced The included 28 male Sprague-Dawley rats, randomly divided into control group, fostamatinib colitis group...
There are only a few epidemiological study about inflammatory bowel disease in the last 10 years Turkey, especially Western Blacksea region. In our study, we aimed to identify changes incidence and prevalence of region at years.Totally 223 patients with inf lammatory (160 ulcerative colitis, 63 Crohn's disease) were enrolled followed up between 2004 2013 years. The characteristics recorded.The prevalences 12.53/105 31.83/105 for colitis respectively. Mean annual incidences increased from...
Aim In this study, we aimed to define the predictive role of liver function tests at admission hospital in outcomes hospitalised patients with COVID-19. Material and Method multicentric retrospective a total 269 adult (≥18 years age) confirmed COVID-19 who were for treatment enrolled. Demographic features, complete medical history laboratory findings study participants obtained from records. Patients grouped regarding their intensive care unit (ICU) requirements during hospitalisation...
A case-control study in the population of Eastern Black Sea region Turkey was conducted to learn incidence stomach cancer siblings patients with gastric carcinoma. Among 1240 carcinoma, 168 had sibling(s) a history versus 19 cases control group matched according age and gender (OR 10.07, P < 0.0001). The frequency cancers other organs first- third-degree relatives 60.7% 38.0%, respectively, sibling carcinoma (P Fifty-two point three per cent having their also reported same-degree relatives....
A case–control study in a population from the Eastern Black Sea region of Turkey was performed to evaluate risk gastric cancer development patients with reporting or other organ history their parents. Gastric and/or parents were found 215 1240 versus 73 controls (odds ratio (OR) 3.35, P<0.001). The frequency among significantly different between and (148 25, respectively; OR 6.59, not (63 48, 1.33, P>0.05). higher than (OR 4.51, first- third-degree relatives 14.72, Familial clustering...
The present study was conducted to characterize the possible therapeutic effects of glucagon-like peptide (GLP)-1 and GLP-2 against oxidative damage in ileum colon irradiated rats. Sprague-Dawley rats both sexes received either a single dose GLP-1 (0.1 nmol/kg, intraperitoneally, ip; n = 6) 10 min before abdominal irradiation (IR) or two consecutive doses (7 at 30 IR, while another group administered vehicle (n IR. Control treatment without On fourth day samples from were removed for...
Inflammatory bowel diseases are chronic, relapsing, inflammatory conditions. They have a genetic backround resulting in patient susceptibility. The aim of our study is to investigate the involvement IL23R, JAK2, and STAT3 polymorphisms Turkish population.Polymorphisms IL23R (rs11209026), JAK2 (rs10758669), (rs3816769, rs2293152, rs744166, rs957970, rs8074524) were genotyped 69 Crohn's disease patients, 157 ulcerative colitis 89 healthy controls.The presence (C) rs10758669, (T) (TT) rs744166...
Background and aim: The aim of this study is to evaluate whether the long-term (≥4 weeks) use proton pump inhibitors (PPIs) a risk factor for intubation requirement mortality in patients hospitalized COVID-19. Materials methods: In multicentric retrospective study, total 382 adult (≥18 years age) with confirmed COVID-19 who were treatment enrolled. divided into two groups according periods during which they used PPIs: first group included not on PPI treatment, second those have PPIs more...
Abstract The HCC‐RESCUE score was developed to predict hepatocellular carcinoma (HCC) risk in Korean chronic hepatitis B (CHB) patients under entecavir therapy. We aimed validate the HCC Caucasian CHB or tenofovir therapy and compare predictive performance of with those CAMD, PAGE‐B modified (mPAGE‐B) scores. study included 647 nucleos(t)ide analogue‐naive noncirrhotic compensated/decompensated cirrhotic who had received for ≥6 months did not develop during first 6 Patients scores ≤64, 65–84...
Inflammation plays an important role in the development of cardiovascular disease, including atherosclerosis and arrhythmia. The aim this study was to evaluate atrial conduction times (ACTs) patients with inflammatory bowel disease (IBD) which systemic chronic inflammation is evident.In cross-sectional, prospective, single-center study, 79 IBD (51 ulcerative colitis; 28 Crohn's disease) 70 healthy controls were included. Atrial electromechanical properties measured by recording simultaneous...
Background and aim: this study aimed to compare carotid intima media (CIMT) epicardial adipose tissue (EAT) measurements, which are considered as markers for the detection of early atherosclerosis in healthy controls inflammatory bowel disease (IBD) cases. Methods: a total 60 IBD patients (25 Crohn’s 35 ulcerative colitis) (as control group) were included study. The measurements CIMT EAT performed using echocardiography ultrasonography, respectively. Statistical analysis was used determine...