A5045797073- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- Psoriasis: Treatment and Pathogenesis
- Ocular Diseases and Behçet’s Syndrome
- Autoimmune Bullous Skin Diseases
- Systemic Sclerosis and Related Diseases
- Urticaria and Related Conditions
- Hypertrophic osteoarthropathy and related conditions
- Eosinophilic Disorders and Syndromes
- Systemic Lupus Erythematosus Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Sarcoidosis and Beryllium Toxicity Research
- Brucella: diagnosis, epidemiology, treatment
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders
- Pulmonary Hypertension Research and Treatments
- Renal Diseases and Glomerulopathies
- Dermatology and Skin Diseases
- Melanoma and MAPK Pathways
- Dermatological and Skeletal Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Ministry of Health
2009-2025
Kahramanmaraş Sütçü İmam University
2020-2024
Sağlık Bilimleri Üniversitesi
2017-2023
University of Health Sciences
2020-2022
Bezmiâlem Vakıf Üniversitesi
2014-2022
University of Health Science
2022
Hacettepe University
2013-2021
Education Training And Research
2009-2021
Memorial Ankara Hospital
2020
Small and Medium Enterprises Development Organization
2020
Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients with psoriasis or PsA have family history PsA, which may affect disease features. The aim this study was to assess the effects and on phenotypes.Data from 1,393 recruited in longitudinal, multicenter Arthritis International Database were analyzed. and/or characteristics investigated using logistic regression.A total 444 (31.9%) had PsA. These more frequently women, earlier onset psoriasis, frequent nail...
Objective. Patient-reported outcomes (PROs) are increasingly accepted to be among the major tools for outcome assessment in rheumatic disorders. In this study we aimed assess quality of life (QoL), disability, anxiety and depression patients with Takayasu's arteritis (TAK).
Approximately 30-45% of patients with familial Mediterranean fever (FMF) have been reported to attacks despite colchicine treatment. Currently, data on the treatment colchicine-unresponsive or colchicine-intolerant FMF are limited; most promising alternatives seem be anti-interleukin-1 (anti-IL-1) agents. Here we report our experience off-label use anti-IL-1 agents in a large group patients.In all, 21 centers from different geographical regions Turkey were included current study. The medical...
To assess bladder toxicity of cyclophosphamide (CYC) and uroprotective effect mesna in rheumatic diseases.Data 1018 patients (725 women/293 men) treated with CYC were evaluated this retrospective study. All the following information was obtained: cumulative dose, route administration, duration therapy, concomitant usage, hemorrhagic cystitis. Cox proportional hazard model used for statistics.We identified 17 (1.67%) cystitis 2 (0.19%) cancer 4224 patient-years. The median time diagnosis to...
Background Eczema is one of the most prevalent occupational skin diseases, with sea fishers being particularly vulnerable due to their harsh working conditions. Objective This study aimed assess prevalence eczema among and identify risk factors contributing its development. Methods A total 119 participated in this cross-sectional study, which was conducted a single center on Mediterranean coast Turkey. Data were collected using two instruments: “General Characteristics Fishers Form,”...
Aim: This study aimed to evaluate the knowledge and attitudes of family physicians health personnel who are responsible for childhood vaccination services in primary care regarding meningococcal, rotavirus, human papillomavirus vaccines. Methods: cross-sectional was conducted between October 2021 January 2022. A total 700 healthcare professionals from all geographical regions Turkey were included study. The participants filled out an online questionnaire consisting 39 questions created with...
Abstract Aim Familial Mediterranean fever ( FMF ) is the most common autoinflammatory disease. One of characteristics this disease its young age predominance. Nearly 90% patients experience flares during early adult periods. Currently there are limited data for comparison versus late onset and therefore primary aim study was to investigate these two subsets with regard their certain demographic, clinical genetic differences. Methods Early (≤ 20 years, Group 1) (> 2) were identified from...
Background The present study was conducted to investigate the association between haematologic indices, neutrophil/lymphocyte ratio (NLR), mean platelet volume (MPV), platelet/lymphocyte (PLR), disease activation, organ involvement, and inflammatory markers in SS. Methods with newly diagnosed treatment-naive 41 primary SS patients who met ACR-2012 criteria 96 healthy volunteers. Blood tests obtained before treatment were evaluated. Lymphocyte, neutrophil counts, corpuscular (MCV),...
TURKBIO registry, established in 2011, is the first nationwide biological database Turkey. This study aimed to provide an overview of data collected by June 2018.The registry included adult patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), nonradiographic axial spondyloarthritis (nr-AxSpA), and psoriatic (PsA). Demographic clinical features, disease activity markers, other follow-up parameters, current previous treat- ments, adverse events were registered electronically...
We present two PHO siblings having a novel homozygous truncating mutation in HPGD. The purpose of the study was to attempt medical treatment, and find HPGD causing disease, 22-year old Turkish male his 23-year sister afflicted with primary hypertrophic osteoarthropathy (PHO). In combination NSAIDs colchicine, treatment sulfasalazine started both cases, methotrexate added regimen female patient at end first year. patients were found be typical PHO. Ultrasonographic examination joints revealed...
We present two PHO siblings having a novel homozygous truncating mutation in HPGD. The purpose of the study was to attempt medical treatment, and find HPGD causing disease, 22-year old Turkish male his 23-year sister afflicted with primary hypertrophic osteoarthropathy (PHO). In combination NSAIDs colchicine, treatment sulfasalazine started both cases, methotrexate added regimen female patient at end first year. patients were found be typical PHO. Ultrasonographic examination joints revealed...
The aim of the study was to investigate whether there is a relationship between European League Against Rheumatism (EULAR) outcome measures and quality life (QoL), fatigue, anxiety depression in patients with pSS define determinants which could affect life.The included 105 72 age/sex-matched healthy controls (HCs). Cross-sectional clinical data were collected, including Hospital Anxiety Depression Scale (HADS), Multidimensional Assessment Fatigue (MAF) scale, Short Form (SF-36), EULAR...
To investigate corneal, scleral, choroidal, and foveal thicknesses in female patients with rheumatoid arthritis (RA) compare them healthy subjects.This prospective study included consecutive diagnosed RA subjects. Corneal, retinal (foveal) were obtained by using optical coherence tomography a comparison was performed between groups for all outcome measures.Thirty-six eyes of 36 (group 1) volunteers 2) included. Mean choroidal thickness at the fovea group 1 543.3±33.7 µm, 343.7±42.2 214.6±50,...
Cardiac complications from brucellosis are unusual and usually manifest as endocarditis. The other possible complication is myocardial involvement. Brucella myocarditis development of heart failure a very rare brucellosis. We present patient with new onset due to brucella treated favorable antibiotic therapy.
One of the major problems for systemic sclerosis (SSc) patients is suggested to be articular involvement. Mostly involved joints in SSc were reported as wrist, carpometacarpal-interphalangeal, foot, knee, hip and shoulder; however, there has been little knowledge on sacroiliac joint. Our aim was evaluate joint involvement SSc.Fifty-seven patients, 54 rheumatoid arthritis 64 healthy subjects included. Anteroposterior pelvic radiographs obtained graded twice by three blinded rheumatologists....