- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Inflammasome and immune disorders
- Spondyloarthritis Studies and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Dermatologic Treatments and Research
- Eosinophilic Disorders and Syndromes
- Streptococcal Infections and Treatments
- Vitamin D Research Studies
- Autoimmune and Inflammatory Disorders
- Obsessive-Compulsive Spectrum Disorders
- Autoimmune and Inflammatory Disorders Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hematological disorders and diagnostics
- Eating Disorders and Behaviors
- Hepatitis B Virus Studies
- Celiac Disease Research and Management
- IL-33, ST2, and ILC Pathways
- Hepatitis C virus research
- Eosinophilic Esophagitis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Blood Coagulation and Thrombosis Mechanisms
Cukurova University
2015-2025
Fırat University
2024
Hacettepe University
2024
Ege Üniversitesi Tıp Fakültesi Hastanesi
2021
Marmara University
2017
Center for Rheumatology
2015
Başkent University
2007
Recurrent aphthous stomatitis is one of the most common lesions oral mucosa. Helicobacter pylori suggested as etiological agents recurrent stomatitis. Here, we conduct a study for evaluating impact H. eradication on clinical course stomatitis.Forty-six patients with minor were enrolled. The number RAS at last 6 months and vitamin B(12) levels recorded. All detected endoscopic biopsy. was positive in 30 negative 16 patients. pylori-positive received therapy. Three after therapy, re-evaluated...
Summary The cyclic alternating pattern (CAP) is a variation of sleep electroencephalogram activity within non‐rapid eye movement (non‐REM) and increased CAP the marker instability. present study aimed to examine expression in non‐REM patients with systemic sclerosis (SSc) compare these findings control group. Thirty‐one SSc were compared matched controls by age, gender, body mass index, apnea–hypopnea index (AHI). Sleep measurements obtained standard polysomnography conventional scoring. A...
Previous studies have indicated that vitamin D deficiency is common in psychiatric patients, particularly those with neuropsychiatric disorders such as autism and schizophrenia. Vitamin an important neurosteroid hormone immunomodulatory agent also has bone metabolic effects. There been increasing interest immune-related symptoms are triggered by group A beta-hemolytic streptococcal infections. In this study, we aimed to compare the serum levels of between obsessive-compulsive disorder (OCD)...
Purpose: To evaluate choroidal thickness (CT) and investigate the involvement of circulation in patients with systemic sclerosis (SSc).Methods: A total 120 eyes 60 SSc 30 healthy controls were evaluated. CT measurements performed at subfoveal region, 1000 µm nasal temporal to fovea, using enhanced depth imaging optical coherence tomography. compared between controls.Results: The average subfoveal, parafoveal significantly thinner when (297.77 ± 60.8 vs 339.8 50.4 µm; 267.32 51.1 308.65 49.9...
The aim of the present study was to investigate whether Helicobacter pylori causes or triggers recurrent aphthous stomatitis (RAS) through cytokine gene polymorphism and/or cobalamin deficiency.Thirty-six patients with RAS and 130 without were genotyped for IL-1β (-511C/T) IL-6 (-174G/C) evaluated H. infection serum level.The patient groups according had similar rates gastritis interleukin genotypes/alleles, there a non-significant difference between levels (p>0.05). showed higher frequency...
Objective: Major differences in sleep architecture are observed patients with systemic sclerosis (SSc).The aim of this study was to investigate the pattern and frequency obstructive apnea (OSA) SSc, compare patterns without pulmonary hypertension (PH).Materials Methods: Patients SSc symptoms hypersomnia or insomnia who underwent polysomnography examinations were evaluated.The clinical data obtained from patient files.The subjects separated into two groups (PH-positive PH-negative).OSA...
Abstract Objectives Connective tissue-associated interstitial lung diseases (CTD-ILD) are believed to be caused by microvascular damage. The objective of this study was assess the nailfold capillaroscopy (NFC) pattern in patients diagnosed with both CTD-ILD and non-CTD-ILD identify changes determine relation between capillaroscopic parameters, clinical variables, disease-related measurements. Patients methods This cross-sectional included 95 disease who applied our Rheumatology Chest Clinics...
One of the major problems for systemic sclerosis (SSc) patients is suggested to be articular involvement. Mostly involved joints in SSc were reported as wrist, carpometacarpal-interphalangeal, foot, knee, hip and shoulder; however, there has been little knowledge on sacroiliac joint. Our aim was evaluate joint involvement SSc.Fifty-seven patients, 54 rheumatoid arthritis 64 healthy subjects included. Anteroposterior pelvic radiographs obtained graded twice by three blinded rheumatologists....
Vitamin D deficiency not only causes low bone mass but also may lead to neuropsychiatric disorders. In the present case, vitamin supplementation reduced obsessive-compulsive disorder (OCD) symptoms associated with streptococcal infection in a 7-year-old boy. Sudden onset of symptoms, including excessive hand washing and fear touching anything, had occurred 1 month before presentation. Although there are few studies on possible causal relationship between disorders, report; together previous...
Genetics is suggested to play a role in the development of Behçet's disease (BD). Shared phenotipic features requires an approach differential diagnosis from periodic febrile syndromes. We planned study for mevalonate kinase (MVK) as candidate susceptibility gene disease.Consecutive Behçet patients and apperently healthy subjects were included. Severity score was calculated. Genotyping performed by polymerase chain reaction/sequence-based typing technique.Fifty BD (median age: 38.30 ± 11.06...
Objectives: This study aims to evaluate the effect of a home-based orofacial exercise program on oral aperture (OA) systemic sclerosis (SSc) patients.
AbstractBackground The frequency of cardiovascular system involvement is increased in rheumatoid arthritis (RA) and may result serious morbidity mortality. Early intervention control the disease activity reduce risk events. purpose this study to examine effects steroids methotrexate (Mtx) on heart functions newly diagnosed RA patients.Methods Our a prospective cohort involving thirty-six patients according American Society Rheumatology classification criteria. Right left ventricular...
This study aims to investigate the correlations between clinical features and mouth opening in patients with systemic sclerosis (SSc).Eighty SSc (13 males, 67 females; mean age 53.39±11.65 years; range, 31 76 years) followed our clinic were enrolled study. Skin involvement was assessed using modified Rodnan skin score (mRSS), joint/tendon finger-tip palm (FTP) distance interstitial lung disease (ILD) evaluated radiologic methods. The interincisal (ID) measurement used assess maximal...
BACKGROUND Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease predominantly affecting populations. The gene associated with FMF the MEFV gene, which encodes for a protein called pyrin. Mutations of pyrin lead to uncontrolled attacks inflammation, and subclinical inflammation continues during attack-free intervals. Killer cell immunoglobulin-like receptor (KIR) genes encode HLA class I receptors expressed by NK cells. aim this study was look immunogenetic...
Reactivation of Hepatitis B (HBVr) related to immunosuppressive drug therapy (ISDT) in patients with resolved and past infection is a challenging entity. The number prospective long-term studies limited.Two groups HBV were analyzed prospectively. further categorized as 266 receiving ISDT (group 1) 246 antineoplastic 2).We did not detect any cases HBVr among 108 rituximab (71 which anti-HBc positive only), 111 tumor necrosis factor inhibitors (66 42 high-dose glucocorticoids for more than 4...