A5067709132- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Salivary Gland Disorders and Functions
- Vasculitis and related conditions
- Cardiac electrophysiology and arrhythmias
- Ocular Diseases and Behçet’s Syndrome
- Systemic Sclerosis and Related Diseases
- Spondyloarthritis Studies and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac Arrhythmias and Treatments
- interferon and immune responses
- Gout, Hyperuricemia, Uric Acid
- Sarcoidosis and Beryllium Toxicity Research
- Autoimmune and Inflammatory Disorders Research
- COVID-19 Clinical Research Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Circular RNAs in diseases
- IL-33, ST2, and ILC Pathways
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Linguistics and Cultural Studies
- Atherosclerosis and Cardiovascular Diseases
Sağlık Bilimleri Üniversitesi
2018-2024
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2015-2024
University of Health Science
2018-2024
University of Health Sciences
2018-2022
Universidad CES
2022
İstanbul Eğitim ve Araştırma Hastanesi
2022
Kayseri Eğitim ve Araştırma Hastanesi
2019-2021
Namık Kemal University
2020
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2020
Şişli Etfal Eğitim ve Araştırma Hastanesi
2018-2019
Electrolyte abnormalities are not uncommon in coronavirus disease 2019 (COVID-19). Several studies have suggested that various electrolyte imbalances seem to an impact on prognosis. However, no study has primarily focused the effect of baseline outcome. In this study, we assessed validity hypothesis may be related unfavourable outcomes hospitalized COVID-19 patients. Design was retrospective and observational. We included 408 individuals with over 18 years old. Baseline levels sodium,...
Approximately 30-45% of patients with familial Mediterranean fever (FMF) have been reported to attacks despite colchicine treatment. Currently, data on the treatment colchicine-unresponsive or colchicine-intolerant FMF are limited; most promising alternatives seem be anti-interleukin-1 (anti-IL-1) agents. Here we report our experience off-label use anti-IL-1 agents in a large group patients.In all, 21 centers from different geographical regions Turkey were included current study. The medical...
Abstract Objective The aim of the present study was to investigate prevalence and pattern cognitive dysfunction observed in primary Sjögren's syndrome (PSS) examine relationships between abilities, depression, fatigue, quality life. Materials Methods Thirty‐two subjects with PSS were compared 19 healthy controls on comprehensive neuropsychological, health state, daily‐life activities tests. Results There low performance Clock Drawing, COWAT, Paced Auditory Serial Addition Test (PASAT),...
Objective. There is often a considerable delay in diagnosis of ankylosing spondylitis (AS). In this multicenter study, we analyzed the and possible associated factors, including an initial lumbar disc herniation (LDH), which frequently encounter daily clinical practice. Methods. The study included 393 consecutive patients [258 men (65.6%), mean age 39.3 ± 10.8 yrs] with AS according to modified New York criteria. Face-to-face interviews were done using structured questionnaire, addressing...
In the case of high erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels, diagnosis underlying disease can be challenging especially in serologically unrevealing patients who have nonspecific clinical findings. We aimed to investigate final distribution definitive diagnoses initially presented with findings sustained elevations serum ESR/CRP levels.The medical records hospitalized a rheumatology clinic between January 2010 2011 were retrospectively analyzed. The...
High-dose steroid has been shown to reduce the mortality rate in Corona virus disease 2019 (COVID-19) patients who need oxygen support. Here, we evaluated effectiveness of pulse-steroid case unresponsiveness treatment with high dose steroid. The study is a retrospective controlled trial. We divided 3 groups: standard-care therapy alone, high-dose (6 mg/day dexamethasone equivalent), and (250 methyl-prednisolone). One hundred fifty were enrolled each group. All hospitalized needed matched...
Abstract Aim Cognitive dysfunction is a neurologic manifestation in primary Sjögren syndrome ( PSS ). On the other hand, several antibodies are related to cognitive dysfunction. The aim of this study assess patients via detailed tests. Moreover, its associations with were also evaluated. Method Twenty‐eight female and 17 healthy controls comprised groups. Short‐term memory, long‐term verbal learning, visual spatial perception, attention, frequency function, executive functions information...
To determine the risk factors for spontaneous pneumomediastinum (SPM), its clinical course and effect on prognosis in patients with Coronavirus disease-19 (COVID-19) pneumonia.Descriptive study.Kayseri City Training Research Hospital, Turkey, from April to September 2020.All COVID-19 patients' clinical, laboratory, radiologic characteristics, as well treatment outcome data, were obtained through medical record extraction. Group A had 50 (22 men 28 women) without SPM, B 20 (10 10...
Background. Systemic amyloidosis is a potentially fatal condition, unless diagnosed and treated before development of irreversible organ damage. Demonstration amyloid deposits within tissue biopsies only definitive diagnostic method, which makes appropriate selection biopsy site essential. Herein, we evaluated efficacy minimally invasive minor salivary gland (MSGB) for the diagnosis amyloidosis. Methods. We analyzed 37 taken from 35 patients. Suggestive findings were significant proteinuria,...
Objective: In this study, we aimed to investigate endothelial functions in primary Sjögren syndrome.Methods: Thirty-five patients with syndrome and 20 age sex-matched healthy volunteers were recruited the present study.Flow mediated dilatation of brachial artery carotid intima-media thickness measured study population.Results: Carotid values similar between groups (0.50 ± 0.10, 0.53 0.08, p > 0.05).Flow was disrupted group (7% vs 12%, = 0.002). Conclusion:There is dysfunction syndrome,...
Objective: Tumor necrosis factor-α (TNF-α) inhibitors are used extensively in the treatment of inflammatory diseases rheumatology, ophthalmology, and neurology.Despite their therapeutic benefits, demyelinating lesions or relapses have been observed following TNF-α inhibitor use. Materials Methods:Of 295 patients who were screened, 258 included study.The demographic characteristics, diagnoses, accompanying diseases, agent(s) used, drug usage, exposure times recorded.The neurological symptoms...
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory characterized by fever, rash, arthritis, and multi-organ involvement. Macrophage activation syndrome (MAS), serious complication of AOSD, poses significant diagnostic therapeutic challenges.
In this study we aimed to investigate myocardial function and atrial electromechanical properties by conventional tissue doppler echocardiography in patients with primary Sjögren syndrome.Forty syndrome (SS) 25 age- sex-matched healthy volunteers were enrolled the study. Using transthoracic echocardiography, performance index measured.Basal characteristics similar between two groups. Myocardial values disturbed (0.41 vs. 0.32, p < 0.01). There was significant intraatrial (16.4±6.4, 5.0±4.5,...
The incidence of contrast-induced nephropathy (CIN) increases in the range from patients with unstable angina to ST-segment elevation myocardial infarction (STEMI). Platelet activation has been associated pathophysiology and thrombus burden infarct-related arteries. We investigated impact on CIN STEMI. enrolled 883 STEMI who received primary percutaneous coronary intervention. Patients were divided into groups according development. Thrombus was scored based thrombolysis grades (TGs). grade...