A5059750084- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Ocular Diseases and Behçet’s Syndrome
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Psoriasis: Treatment and Pathogenesis
- Infectious Diseases and Tuberculosis
- Biosimilars and Bioanalytical Methods
- Tuberculosis Research and Epidemiology
- Chronic Lymphocytic Leukemia Research
- Otitis Media and Relapsing Polychondritis
- Bone and Joint Diseases
- Pulmonary Hypertension Research and Treatments
- Retinal and Optic Conditions
- Renal Diseases and Glomerulopathies
- Atherosclerosis and Cardiovascular Diseases
- Hematological disorders and diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Blood Coagulation and Thrombosis Mechanisms
- Platelet Disorders and Treatments
- Kawasaki Disease and Coronary Complications
Hacettepe University
2016-2025
Center for Rheumatology
1996-2021
Faculty (United Kingdom)
2020-2021
Cukurova University
2016
Bursa Uludağ Üni̇versi̇tesi̇
2016
Ege University
2016
Trakya University
2016
Marmara University
2016
Gaziantep University
2016
Pamukkale University
2016
Recent studies point out a probable role of streptococcal antigens in the pathogenesis Behçet's disease (BD). This has led to proposal benzathine penicillin as therapeutic modality BD.A prospective study was conducted compare efficacy colchicine and + treatments on mucocutaneous manifestations BD.60 patients (group I) were given alone 94 II) penicillin. Frequency, number, duration severity oral aphthous ulcers, genital ulcers erythema nodosum determined before after treatment.In group I, all...
Objective. Screening strategies for latent tuberculosis (TB) before starting tumor necrosis factor (TNF)-α inhibitors have decreased the prevalence of TB among patients who are treated with these agents. However, despite vigilant screening, continues to be an important problem, especially in parts world a high background prevalence. The aim this study was determine factors related large multicenter cohort were anti-TNF. Methods. Fifteen rheumatology centers participated study. Among 10,434...
Abstract Objective . Because exposure to streptococcal antigens might be a major disease activity—provoking factor in Behçet's disease, this study was undertaken evaluate the effectiveness of benzathine penicillin prophylaxis recurrent arthritis episodes during course disease. Methods A prospective, randomized design used allocate patients receive colchicine alone or plus for 24 months. Results The duration, severity, and pattern were found similar 2 treatment groups, but number...
Background: Effectiveness of anti-tumor necrosis factor (anti-TNF) agents in colchicine-resistant familial Mediterranean fever (FMF) patients has attracted attention recent years. Objective: We analyzed the effect anti-TNF on clinical findings FMF with chronic arthritis and/or sacroiliitis. Methods: Data from 10 (5 male and 5 female patients: mean age, 30.1 [SD, 8.5] years) sacroiliitis who were are reviewed. Frequency attacks before after treatment was recorded hospital files. The effects...
Objectives: This study aimed to examine the frequency and associated factors of extra-musculoskeletal manifestations (EMMs) peripheral in an axial spondyloarthritis (axSpA) cohort their impact on choice first biologic treatment. Patients methods: A total 1,687 patients with axSpA (978 males, 709 females; mean age: 38.5±11 years) who started disease modifying antirheumatic drug (bDMARD) were included from a national prospective database TReasure between its inception 2018-2021. Demographic...
Abstract Objective The endothelial damage of microvascular structures in systemic sclerosis (SSc; scleroderma) is associated with increased levels adhesion molecules and endothelium‐associated cytokines, including E‐selectin thrombomodulin. Although there still no ideal specific pharmacologic therapy for SSc, cyclophosphamide has resulted clinical improvement patients SSc‐related active alveolitis. This study was designed to assess the expression thrombomodulin early diffuse investigate...
This study aimed to assess the frequency of all palpable lymph nodes during active disease and remission in patients with rheumatoid arthritis (RA) systemic lupus erythematosus (SLE). Hospital records 100 SLE patients, RA spondyloarthropathy 150 osteoarthritis treated our rheumatology department, were evaluated retrospectively. Overall frequencies enlarged 82% 69%, respectively. Enlarged associated mostly located axillary region, smaller lymphadenopathy was more generalized compared RA....
Background: Cardiac involvement is one of the major problems in systemic sclerosis (SSc). Subclinical cardiac has a higher frequency than thought previously. In this study we investigated whether subclinical can be detected by using echocardiographic strain imaging SSc patients without pulmonary hypertension. Methods: Echocardiographic examinations were performed to 27 and 26 healthy controls. Left ventricular parameters obtained from apical views average value was calculated these...
Abstract Objective Polyarteritis nodosa ( PAN ) is a necrotizing vasculitis of medium/small arteries. We aimed to examine the characteristics adult‐ and childhood‐onset . Methods Fifteen pediatric (˂ 18 years) 22 adult patients who fulfilled Ankara 2008 American College Rheumatology 1990 criteria, respectively, were included in study. Results Five children had cutaneous all rest systemic Weight loss was more common (59.1% vs 20%, P = 0.041) presence an angiography at diagnosis frequent...
Objectives The objective of this study was to report the experience with rituximab treatment in a case series patients long-standing systemic sclerosis–associated interstitial lung disease (SSc-ILD). Methods We reviewed charts 197 SSc patients. Fourteen who received for SSc-ILD participated analysis. Pulmonary function tests, high-resolution thorax computed tomography and modified Rodnan skin scores were evaluated at baseline end follow-up. Results Median age 53.2 years (interquartile range,...