A5046363214- Ocular Diseases and Behçet’s Syndrome
- Otitis Media and Relapsing Polychondritis
- Retinal and Optic Conditions
- Systemic Lupus Erythematosus Research
- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Infectious Diseases and Tuberculosis
- IgG4-Related and Inflammatory Diseases
- Tuberculosis Research and Epidemiology
- Cerebral Venous Sinus Thrombosis
- Inflammatory Bowel Disease
- Spondyloarthritis Studies and Treatments
- Chronic Lymphocytic Leukemia Research
- Vascular Anomalies and Treatments
- Venous Thromboembolism Diagnosis and Management
- interferon and immune responses
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Hepatitis C virus research
- Mycobacterium research and diagnosis
- Kawasaki Disease and Coronary Complications
- Monoclonal and Polyclonal Antibodies Research
Istanbul University-Cerrahpaşa
2016-2025
Istanbul University
2015-2024
University Medical Center Groningen
2023
İstanbul Nişantaşı Üniversitesi
2023
Royal United Hospital
2023
Royal National Hospital for Rheumatic Diseases
2023
Azienda Sanitaria Unità Locale di Reggio Emilia
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Sun Yat-sen Memorial Hospital
2023
Sun Yat-sen University
2023
Since the publication of European League Against Rheumatism (EULAR) recommendations for management large vessel vasculitis (LVV) in 2009, several relevant randomised clinical trials and cohort analyses have been published, which potential to change care therefore supporting need update original recommendations.Using EULAR standardised operating procedures EULAR-endorsed recommendations, task force undertook a systematic literature review sought opinion from 20 experts 13 countries. We...
To develop evidence-based European League Against Rheumatism (EULAR) recommendations for the management of Behçet disease (BD) supplemented where necessary by expert opinion.The multidisciplinary committee, a task force EULAR Standing Committee Clinical Affairs (ESCCA), consisted nine rheumatologists (one who was also clinical epidemiologist and one Rehabilitation Medicine doctor), three ophthalmologists, internist, dermatologist neurologist, representing six countries plus Tunisia Korea. A...
Several new treatment modalities with different mechanisms of action have been studied in patients Behçet's syndrome (BS). The aim the current effort was to update recommendations light these data under auspices European League Against Rheumatism (EULAR) Standing Committee for Clinical Affairs. A task force formed that included BS experts from specialties including internal medicine, rheumatology, ophthalmology, dermatology, neurology, gastroenterology, oral health medicine and vascular...
Oral ulcers, the hallmark of Behçet's syndrome, can be resistant to conventional treatment; therefore, alternative agents are needed. Apremilast is an oral phosphodiesterase-4 inhibitor that modulates several inflammatory pathways.
The small-molecule phosphodiesterase 4 inhibitor apremilast modulates cytokines that are up-regulated in Behçet's syndrome. In a phase 2 trial involving patients with syndrome, reduced the incidence and severity of oral ulcers. Data on efficacy safety syndrome who had active ulcers not previously received biologic agents limited.
Pulmonary artery aneurysms (PAAs) are well known causes of mortality and morbidity in Behçet disease (BD). However, pulmonary involvement BD is not limited to PAA; the other main type thrombus (PAT), with or without associated PAA. In addition, types lung like nodules cavities parenchyma frequently involvement, can be misinterpreted as being due infection. We surveyed clinical, radiologic, laboratory characteristics outcome 47 patients findings, all seen followed at a single dedicated...
Abstract Objective Behçet's syndrome is characterized by clusters of disease expression, one which the coexistence acne and arthritis. The aim this study was to test hypothesis that enthesopathy increased in cluster, having features reminiscent acne‐associated Methods group comprised 35 patients with who had arthritis (BS‐AA), 38 did not have (BS‐WA), 37 ankylosing spondylitis (AS), 25 rheumatoid (RA), healthy control subjects. Five entheseal sites (the superior inferior poles patella,...
Gastrointestinal involvement is rare in Behçet's syndrome (BS) patients from the Mediterranean basin. We report demographic and disease characteristics, treatment modalities, outcome of with gastrointestinal BS (GIBS). retrospectively reviewed charts all our clinic a diagnosis GIBS. Patients were invited to assess their outcome. Among 8763 patients, we identified 60 GIBS (M/F: 32/28, mean age at diagnosis: 34 ± 10, follow-up: 7.5 4 years), after excluding 22 mimicking symptoms. Six (10%) had...
Objective. Screening strategies for latent tuberculosis (TB) before starting tumor necrosis factor (TNF)-α inhibitors have decreased the prevalence of TB among patients who are treated with these agents. However, despite vigilant screening, continues to be an important problem, especially in parts world a high background prevalence. The aim this study was determine factors related large multicenter cohort were anti-TNF. Methods. Fifteen rheumatology centers participated study. Among 10,434...