Heat shock proteins (HSPs) are expressed by most living cells and play fundamental roles in many biological processes. Their synthesis increases a variety of stresses order to enable cellular survival. Although it is known that they an important role immune inflammatory responses the skin, HSPs pathogenesis skin diseases has been studied only limited diseases. Lichen planus (LP) relatively common papulosquamous dermatosis, cell-mediated immunity plays its pathogenesis. altered expression...

Helicobacter pylori is now regarded as a major gastroduodenal pathogen that etiologically linked with duodenal and gastric disease. It has been suggested recently an important factor for nongastroenterologic conditions such coronary heart disease diabetes mellitus. In this study, we planned to investigate the prevalence of H. in diabetic patients evaluate five different diagnostic tests.Group I consisted 67 type II mellitus seventy-three aged-matched health people served control group II....

In dieser Studie wurde der Einfluss von Melatonin auf eine nekrotisierende Pankreatitits (ANP) bei Ratten untersucht. Die Entstehung einer ANP führt zu einem signifikanten Anstieg Mortalität, Pankreasnekrosen, zur Zunahme Serumaktivität Amylase, Alanin-Aminotransferase (ALT) und Interleukin 6 (IL-6), Laktatdehydrogenase (LDH) in bronchoalveolären Lavage (BAL), zum Serumkonzentration Harnstoff, Gewebeaktivität Myeloperoxidase (MPO) Malondialdehyd (MDA) im Pankreas Lunge sowie Abfall Kalzium,...

Objective Lymphoscintigraphy (LS) and sentinel lymph node biopsy have become the standard of care for melanoma breast cancer. However, data on patients with cutaneous squamous cell carcinoma (SCC) are limited. We aimed to evaluate identify role LS in high-risk SCC. Methods Nineteen (13 men, six women; 47–87 years age, mean age 67.5±12.3) SCC were included study. was performed all after intracutaneous injection Tc-99m nanocolloid. Primary lesions nodes (SLNs) excised help a gamma probe....

The aim of this study was to investigate the influence ofω–3 fatty acids (ω3FA) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. induction ANP resulted significant increases mortality rate, intestinal permeability, bacterial infection pancreas and extrapancreatic organs, serum activity urea amylase, alanine transferase (ALT), interleukin (IL)-6, tumor factor-α (TNF-α), lactate dehydrogenase (LDH) bronchoalveolar lavage (BAL) fluid, tissue myeloperoxidase...

Breast cancer is a heterogeneous disease with different histological types. Ductal breast constitutes the vast majority of cancers. However limited data are present in rest cancers called special or rare type Here this study, we tried to describe clinical features our center.Retrospective descriptive study was performed Kocaeli University School Medicine, Department General Surgery between January 2000 and 2016. Women diagnosed primary other than ductal carcinoma were included study. In...

We report a case of Noonan syndrome associated with central giant cell granuloma. The patient was 101/2‐year‐old boy the chief complaint proptosis right eye. He also had various malformations such as short stature, webbed neck, pectus excavatum, cubitus valgus, pulmonary valve stenosis and patent foramen ovale, characteristic face appearance cryptorchidism so on. Chromosome analysis showed 46, XY karyotype. A computed tomographic scan magnetic resonance imaging mass originated from lateral...

Littoral cell angioma (LCA) of the spleen is a relatively recently described rare entity, which associated with haemophagocytosis. In this case report, we will present myelodysplastic syndrome multiple LCA spleen. The patient presented pancytopenia and haemangiomas were observed in during diagnostic abdominal ultrasound. She required transfusion one to two units packed blood every 4-6 weeks she eventually underwent splenectomy order decrease requirement. Although patient's improved after...

Gout is a common metabolic disease and characterized by episodic acute chronic arthritis caused the deposition of monosodium urate (MSU) crystals in joints connective tissues. The most commonly involved joint first metatarsophalangeal joint. It may also present with nonspecific complaints gouty tophi unusual sites body such as spine, bone, middle ear. Such involvements can be disabling impair quality life. In this report, we describe case patient who had hearing loss otorrhea. A 34 year-old...

Anetoderma is an uncommon disorder characterized by the loss of elastic fibres in dermis histologically and herniation subcutaneous tissue clinically. Recent studies indicate that immunologic mechanisms may play a role this process. Here we report 33-year-old woman with numerous well-circumscribed, asymptomatic skin lesions whom clinical histopathologic features were consistent anetoderma. Additionally, history investigations revealed antiphospholipid syndrome systemic lupus erythematosus....

Objective and Importance: The authors present a rare case of primary cranial vault lymphoma, mimicking subacute subdural hematoma after head trauma. Clinical Presentation: A 78-year-old woman was admitted to the hospital with progressive left hemiparesis, headache gradually increasing soft lump over right parietal region 1 week trauma due falling from high place. computed tomography (CT) scan demonstrated hyperdense parieto-occipital subgaleal lesion together marked midline shift white...

The aim of this study was to investigate the influence U-74389G on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. induction ANP resulted a significant increase mortality rate, pancreatic necrosis, and serum levels amylase, alanine aminotransferase, interleukin-6, tumor necrosis factor alpha, urea, lactate dehydrogenase bronchoalveolar lavage fluid, activities myeloperoxidase malondialdehyde pancreas lung tissue; decrease observed calcium levels, blood...

<b>Background</b> Autofluorescence (AF) examination in thoracoscopy has not been used frequently. Here, our aim was to determine whether AF contributes additional information white-light (WL) when attempting detect malignant pleural lesions. We also liked know the effectiveness of WL and AF-mode combination would be different for various pathologies or lesions pleura. <b>Methods</b> It is a retrospective study. Thirty-three patients with unexplained exudative effusions underwent AF-assisted...

The aim of this study was to investigate the influence N-acetylcysteine (NAC) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. induction ANP resulted significant increase mortality rate, pancreatic necrosis and serum activity amylase, alanine aspartate transferase (ALT), interleukin-6 (IL-6), lactate dehydrogenase (LDH) bronchoalveolar lavage (BAL) fluid, concentration urea, tissue myeloperoxidase (MPO) malondialdehyde (MDA) pancreas lung, decrease...

The aim of this study was to investigate the dose-dependent anti-inflammatory effect Hydrogen sulfidedonor sodiumhydrosulphide on acute necrotizing pancreatitis in rats.A total 42 male Sprague-Dawley rats were divided into 4 groups: sham+saline (group 1), sham+NaHS 2), pancreatitis+saline 3), and pancreatitis+NaHS 4). Acute induced groups 3 with infusion glycodeoxycholic acidinto biliopancreatic canal cerulein parenterally. In group 4, 10 mg/kg NaHS administered intraperitoneally after...