- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Cancer Diagnosis and Treatment
- Pneumothorax, Barotrauma, Emphysema
- Sarcoma Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ultrasound in Clinical Applications
- Cardiac tumors and thrombi
- Uterine Myomas and Treatments
- Tracheal and airway disorders
- Parathyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Hedgehog Signaling Pathway Studies
- Thyroid Cancer Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- Bone Tumor Diagnosis and Treatments
- Renal cell carcinoma treatment
- Lung Cancer Treatments and Mutations
- Soft tissue tumor case studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Thyroid and Parathyroid Surgery
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
Eskişehir Osmangazi University
2011-2024
Sağlık Bilimleri Üniversitesi
2019
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2019
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2006-2017
Eskişehir City Hospital
2012-2013
Penn State Milton S. Hershey Medical Center
2001
Pennsylvania State University
2001
Johns Hopkins University
1999
Palmetto Hematology Oncology
1998
<b><i>Background:</i></b> Image-guided pleural biopsies, both using ultrasound (US) or computed tomography (CT), are important in the diagnosis of disease. However, no consensus exists regarding which biopsy needles appropriate for specific procedures. <b><i>Objectives:</i></b> In this randomized, prospective study, we aimed to compare CT scan-guided an Abrams' needle (CT-ANPB) with US-assisted a cutting (US-CNPB) respect diagnostic yield and...
Introduction . We investigated the expression of microRNAs and mRNAs in pleural tissues from patients with either malignant mesothelioma or benign asbestos-related effusion. Methods Fresh frozen a total 18 6 effusion were studied. Expression profiling mRNA microRNA was performed using standard protocols. Results discovered significant upregulation multiple compared to Hsa-miR-484, hsa-miR-320, hsa-let-7a, hsa-miR-125a-5p able discriminate disease. Dynamically regulated also identified. MET...
Abstract Purpose There are currently no methods to predict response chemotherapy in pleural mesothelioma (PM). The aim of this study is investigate the predictive and prognostic role BAP1, WT1 calretinin expression their combinations pre-treatment tumor samples by immunohistochemical (IHC) staining. Methods included consecutive PM patients treated with alone at a University hospital between 2009 2020. BAP1 analyses were performed on formalin-fixed, paraffin-embedded tissue patients, while...
This study investigated whether microvessel density (MVD) and mast cell infiltration are related to prognosis in non-small lung carcinoma (NSCLC), examined the possible role of cells NSCLC angiogenesis. MVD were analysed retrospectively tumour specimens from 50 patients with primary NSCLC. Immunohistochemistry monoclonal antibody anti-CD34 was used delineate microvessels routine Giemsa blue staining assess number cells. Significant correlations found between both lymph node metastasis...
In many cases communicating hydrocephalus is the result of impairments in cerebrospinal fluid absorption arachnoid villi at cranial convexity. Reported methods creating experimental have not sought to produce an arachnoidal adhesion this study authors investigate alterations cerebral blood flow (CBF) induced by injection kaolin into subarachnoid space convexity neonatal rats.In rats, was injected Assessment CBF performed using transcranial Doppler ultrasonography preinjection and 10 days, 4...
<b>Objectives</b> In this study, we aimed to define the efficacy of F-18 FDG PET/CT for detection mediastinal lymph node metastases by comparing findings with histopathological results obtained either mediastinoscopy or thoracotomy in patients clinically operable non-small cell lung cancer (NSCLC). <b>Material and Methods</b> This is a prospective, single-institution study 68 consecutive suspected pathologically proven, localized, resectable NSCLC (8 females 60 males; mean age: 60.36 ± 1.01...
Background: The use of medical thoracoscopy (MT) for the diagnosis and/or palliative treatment pleural effusions is expected to become more widespread in coming years. aims present study were establish safety MT a group patients at high risk complications and determine factors that affect development complications. Methods: A total 355 who underwent divided into 2 groups: had no factor. After procedure, recorded. All followed up least 24 months. To evaluate relationship between variables...
<i>Objective:</i> To describe an unusual case of acute liver failure due to Hodgkin’s lymphoma. <i>Case Presentation and Intervention:</i> A 37-year-old man was admitted with jaundice abdominal distension. Physical examination showed tender hepatosplenomegaly, ascites, grade I encephalopathy, left cervical (2 × 1 cm) axillary (1 lymph nodes. The laboratory data revealed elevated serum bilirubin, transaminases, lactate dehydrogenase, coagulation defects. Initially,...
Abstract Background Mesothelioma is a malignant neoplasm with poor survival rate. We aimed to investigate the importance of BAP1, MTAP (IHC), and p16/CDKN2A homozygous deletion (FISH) in cytologic material obtained from pleural effusion sampling, which less invasive procedure diagnosis mesothelioma. Methods Our study discussed cytology samples cases histopathologically proven mesothelioma diagnoses between 2017 2022. As control group, materials that had sampling for other reasons reactive...
Every year, lung cancer contributes to a high percentage deaths in the world. Early detection of is important for its effective treatment, and non-invasive rapid methods are usually used diagnosis.In this study, we aimed detect using deep learning determine contribution classification carcinoma convolutional neural network (CNN).A total 301 patients diagnosed with pathologies our hospital were included study. In thorax, Computed Tomography (CT) was performed diagnostic purposes prior...
We studied the effects of clonidine (0.5 mg/kg) on hormonal stress response and antioxidant enzymes cold restraint-induced gastric lesions in rats. Rats study group were given 0.5 mg/kg intraperitoneal (n = 12), whereas control received mL/kg isotonic sodium chloride solution 9). Animals then subjected to immobilization at 4 degrees C restraining devices for h after a starvation period 24 h. Gastric lesion index, tissue malondialdehyde activity, plasma cortisol concentrations assayed....
<b><i>Background:</i></b> Elevated serum C-reactive protein (CRP) level has been demonstrated to predict poorer survival of both localized and metastatic renal cell carcinoma. However, the prognostic value intratumoral CRP expression not sufficiently studied. <b><i>Patients Methods:</i></b> In present study, was evaluated with immunohistochemical analysis in 127 patients who had undergone curative surgery for clear staining scored using...
Gout is a common metabolic disease and characterized by episodic acute chronic arthritis caused the deposition of monosodium urate (MSU) crystals in joints connective tissues. The most commonly involved joint first metatarsophalangeal joint. It may also present with nonspecific complaints gouty tophi unusual sites body such as spine, bone, middle ear. Such involvements can be disabling impair quality life. In this report, we describe case patient who had hearing loss otorrhea. A 34 year-old...