A5069186616- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Salivary Gland Disorders and Functions
- Rheumatoid Arthritis Research and Therapies
- Otitis Media and Relapsing Polychondritis
- Inflammasome and immune disorders
- Ocular Diseases and Behçet’s Syndrome
- Renal Diseases and Glomerulopathies
- Autoimmune and Inflammatory Disorders Research
- Salivary Gland Tumors Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Immunodeficiency and Autoimmune Disorders
- Psoriasis: Treatment and Pathogenesis
- Biosimilars and Bioanalytical Methods
- Liver Disease Diagnosis and Treatment
- Dermatologic Treatments and Research
- Sarcoidosis and Beryllium Toxicity Research
- Hepatitis C virus research
- Pulmonary Hypertension Research and Treatments
- Urticaria and Related Conditions
- Cardiovascular Disease and Adiposity
- Retinal and Optic Conditions
- Gout, Hyperuricemia, Uric Acid
Kocaeli Üniversitesi
2016-2025
Center for Rheumatology
2015-2022
Ankara University
2020
Although the importance of biopsychosocial models for chronic diseases is emphasized nowadays, lack assessment tools to meet this need draws attention. This study was planned assess validity, reliability, and responsiveness Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) in patients with fibromyalgia.Hospital Anxiety Depression Scale (HADS), Mindful Attention Awareness Scale, Health Assessment Questionnaire, Fibromyalgia Impact Short-Form 36 (SF-36) were used...
Although the frequency of metabolic syndrome has been studied separately in psoriasis, psoriatic arthritis (PsA), and rheumatoid (RA) patients, there is no study that compares prevalence all three diseases. The purpose this to evaluate relationship between (MetS) chronic low-grade inflammatory diseases, determine MetS insulin resistance psoriasis PsA as compared RA.A total 155 patients were included cross-sectional study. Fifty who diagnosed with 55 according CASPAR criteria, 50 seropositive...
Objective This retrospective study aimed to conduct a comprehensive analysis of Turkish Systemic Lupus Erythematosus (SLE) patients Caucasian ethnicity, focusing on their clinical, immunological, and therapeutic characteristics, damage accural mortality. Patients Methods We carried out assessment 300 SLE diagnosed between 2001 2017 at Kocaeli University Rheumatology Clinic. Demographic data, clinical manifestations, immunological profiles, treatment approaches, disease-related damage,...
Objective Familial Mediterranean Fever (FMF) is an autoinflammatory disease that commonly present with recurrent episodes of fever, peritonitis, pleuritis or arthritis. Enthesitis and sacroilitis can also be seen in FMF. Spondylitis a less common manifestation joint involvement FMF there are controversial publications about whether this FMF-related coincidentally. The aim study was to provide comparison between ankylosing spondylitis (AS) patients AS. Methods A total 404 who 360 them AS 44...
Sjögren's syndrome is a systemic, autoimmune disease and can affect many organs systems. In this study, we aimed to evaluate the respiratory manifestations, association between interstitial lung (ILD) activity in primary SS (pSS) patients.The study design was retrospective cross-sectional, 151 patients followed up with diagnosis of pSS 2004 2019 were included study. Demographic clinical data, laboratory results, chest radiographs thorax computed tomography (CT) results obtained from patient...
Abstract Hyperimmunoglobulin D syndrome (HIDS) is a rare autoinflammatory disorder with autosomal recessive inheritance. It caused by specific mutations in the mevalonate kinase gene (MVK). No treatment to HIDS has been approved date; however, nonsteroidal anti‐inflammatory drugs, steroids, colchicine, tumor necrosis factor‐α inhibitors, and anti‐interleukin‐1 treatments are used, based on case reports observational studies. Herein, we report recurrent fever arthritis attacks who did not...
<h3>Background</h3> Familial Mediterranean Fever (FMF) is autosomal ressesive disease which commonly seen in mediterrenean countries with recurrent episodes of fever, peritonitis, pleuritis, arthritis, or erysipelas-like erythema. Some FMF patients develop sacroilitis and spondyloarthropatis. Ankylosing Spondilitis (AS) a within spondyloarthritis group characterized by inflammation the axial joints, peripheral oligoarthritis, enthesitis. <h3>Objectives</h3> The aim this study was to provide...
Psoriatic arthritis (PsA) is a chronic inflammatory disease in the spondyloarthropathy group with history of psoriasis. Although some PsA findings are similar to rheumatoid (RA), factor negativity, radiological and clinical different PsA. There no spesific laboratory examination for diagnosis On other hand, anti-CCP antibody positivity finding RA. Objectives: We aimed this study analyse frequency association findings. Methods: The consisted 100 patients, who fulfilled CASPAR cirteria healthy...
Amaç: Primer Sjögren sendromu (pSS), ekzokrin bezlerin lenfositik infiltrasyonu ile karakterize, birçok organı etkileyen sistemik, otoimmün bir hastalıktır.Glutene karşı gelişen immünolojik yanıt sonucu ortaya çıkan Çölyak hastalığı (ÇH), ince bağırsakta enflamatuvar hasara neden olur.ÇH'nin pSS'de insidansı artmıştır.Bu araştırmanın amacı, ÇH sıklığını incelemektir.Yöntem: Bu çalışma, 2019-2020 yılları arasında tek merkezde yürütülen kesitsel çalışmadır.pSS tanısı alan toplam 90 hasta,...
Abstract Tocilizumab (TCZ) is a recombinant humanized monoclonal antibody that targets the IL-6 receptor. TCZ found to be efficacious and has good tolerated safety profile in rheumatoid arthritis (RA) patients. The aim of this study was describe disease activity retention rate Turkish RA patients who were prescribed as first-line biologic treatment real-world setting. Secondary data obtained from adult patients’ files used multicenter retrospective context. Clinical Disease Activity Index...
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) belongs to the tumor factor (TNF) superfamily and is reported play a role in autoimmune diseases. In this study, we aimed measure serum TRAIL receptor 1 (TRAIL-R1) concentration assess any phenotypic relationship patients with ankylosing spondylitis (AS).Fifty-three AS were recruited from August 2014 December cross-sectionally. Fifty-three sex- age-matched healthy controls also recruited. Serum TRAIL-R1 concentrations measured...
<h3>Background</h3> Patients with Sjogren's syndrome (SS) have symptoms such as vaginal dryness and dyspareunia. <h3>Objectives</h3> In this study we aimed to present of primary SS (pSS) secondary (sSS) patient's gynecological effects the disease on sexuality. <h3>Methods</h3> 60 pSS, 42 sSS, 52 healthy controls (HC) were interviewed. It was asked questions about sexuality, SF-36, HAD scale, pSS sSS patients also administered HAQ Modified Hiil questionnaire¹. <h3>Results</h3> The mean age ±...
<h3>Background</h3> Risk of cardiovascular mortality is increased in patients with ankylosing spondylitis (AS). Chronic inflammation plays a crucial role the development accelerated atherosclerosis. TNFa pro-inflammatory cytokine which may be key mediator pathophysiology atherogenesis. This reduces activity insulin and causes resistance (IR). <h3>Objectives</h3> We assessed effect infliximab treatment on sensitivity metabolic parameters AS. <h3>Methods</h3> In this prospective study, 20...
Takayasu's arteritis (TAK) is a rare vasculitis characterized by inflammation of intermediate- to large-size arteries. Although pulmonary artery involvement (PAI) an expected finding in some TAK patients, data on non-vascular (NVPI) are limited. We aimed investigate the frequency NVPI, including parenchymal infiltration, nodules/cavities, pleural effusion, and haemorrhage, TAK.We assembled retrospective cohort patients from nine tertiary centres Turkey. The demographics clinical...