A5020214806- Vasculitis and related conditions
- Autoimmune and Inflammatory Disorders Research
- Ocular Diseases and Behçet’s Syndrome
- Salivary Gland Disorders and Functions
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Kawasaki Disease and Coronary Complications
- Hepatitis B Virus Studies
- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Hepatitis C virus research
- Adolescent and Pediatric Healthcare
- Dialysis and Renal Disease Management
- Otitis Media and Relapsing Polychondritis
- Heparin-Induced Thrombocytopenia and Thrombosis
- Intensive Care Unit Cognitive Disorders
- Immunodeficiency and Autoimmune Disorders
- Hepatitis Viruses Studies and Epidemiology
- Bone and Joint Diseases
- Cerebrovascular and Carotid Artery Diseases
- Inflammasome and immune disorders
- Spondyloarthritis Studies and Treatments
- Venous Thromboembolism Diagnosis and Management
- Retinal and Optic Conditions
- Autoimmune Bullous Skin Diseases
Marmara University
2021-2024
Different patient clusters were preliminarily suggested to dissect the clinical heterogeneity in Still's disease. Thus, we aimed at deriving and validating disease a multicentre, observational, prospective study stratify these patients.Patients included GIRRCS AOSD-study group AIDA Network Still Disease Registry assessed if variables for cluster analysis available (age, systemic score, erythrocyte sedimentation rate (ESR), C reactive protein (CRP) ferritin). K-means algorithm with Euclidean...
The effectiveness of canakinumab may change according to the different times it is used after Still's disease onset. This study aimed investigate whether (CAN) shows differences in short- and long-term therapeutic outcomes, its use as lines biologic treatment.Patients included this were retrospectively enrolled from AutoInflammatory Disease Alliance (AIDA) International Registry dedicated disease. Seventy-seven (51 females 26 males) patients with present study. In total, 39 (50.6%) underwent...
Background: The risk of hepatitis B reactivation in surface antigen-negative phase virus-infected patients exposed to biologic agents is not clear.We aimed investigate the rate after therapy.Methods: Patients followed at gastroenterology, rheumatology, and dermatology clinics with a diagnosis immune-mediated inflammatory diseases were screened.Immune-mediated negative antigen positive core immunoglobulin G antibody included study.Results: We screened 8266 disease patients, 2484 identified as...
To characterize clinical and laboratory signs of patients with Still's disease experiencing macrophage activation syndrome (MAS) identify factors associated MAS development. Patients classified according to internationally accepted criteria were enrolled in the AutoInflammatory Disease Alliance (AIDA) Registry. Clinical features observed during inflammatory attack complicated by included univariate multivariate logistic regression analysis A total 414 included; 39 (9.4%) them developed...
Abstract Background Calprotectin is an important molecule in the initiation and progression of inflammatory process. Systemic local intraperitoneal inflammation are distinct processes consequences peritoneal dialysis (PD). We aimed to evaluate dialysate calprotectin levels its associations with peritonitis adequacy PD patients. Methods Forty‐four patients were included this prospective study. concentration was evaluated 24‐h drainage fluid. Patients followed‐up for 1 year, episodes recorded....
Recent studies have evaluated the severity of COVID-19 in patients with iRMD, and it has been reported that glucocorticoid use is associated severe disease (3)(4)(5).Also, risk factors for iRMD were identified as general population, such male gender, older age, hypertension, obesity (6).Strangfeld et al. (7) Aim: Coronavirus disease-2019 (COVID-19) affected more than three hundred million individuals, many increased mortality morbidity defined.There are evaluating course inflammatory...
<h3>Background</h3> In vascular involvement of Behçet's disease (BD), inflammatory cells infiltrate mainly the adventitia and media, but only a few were shown in intima layer during active arteritis.<sup>[1]</sup> We recently showed that increased common femoral vein (CFV) thickness is distinctive feature BD with specificity higher than 80% for cut-off value ≥0.5 mm.<sup>[2]</sup> <h3>Objectives</h3> this study, we aim to investigate localization inflammation wall patients by measuring both...
<h3>Background</h3> Secondary Sjögren's syndrome (sSS) accompanies many systemic rheumatic diseases at certain rates, including axial spondyloarthritis (axSpA).<sup>[1]</sup> There are some case reports in which psoriasis or psoriatic arthritis (PsA) with sSS co-existence.<sup>[2]</sup> However, the prevalence of (PsO) and PsA is not fully addressed. Additionally, clinical laboratory features that may be associated sSS, whether related known. <h3>Objectives</h3> This study aims to assess...
<h3>Background</h3> Sacroiliac joint (SIJ) magnetic resonance imaging (MRI) is an established tool in the evaluation of patients with axial spondyloarthritis (axSpA). In validation study ASAS classification criteria for axSpA, only 63.1% had sacroiliitis on SIJ-MRI.<sup>[1]</sup> Studies that enrolled axSpA based expert opinion reported sensitivity MRI between 35 to 42% detecting sacroiliitis.<sup>[2,3]</sup> <h3>Objectives</h3> This aimed evaluate temporal relationship defined positive and...
<h3>Background</h3> Inflammation of the lacrimal glands leads to ocular dryness, an important cause decreased quality life in primary Sjögren's syndrome (pSS) patients <sup>[1]</sup>. Limited data focuses on dry eye disease (DED) pSS. Previous studies did not conduct a comprehensive evaluation DED using tests measure tear film volume or instability, surface damage, meibomian gland dysfunction, and patient-reported outcomes, activity parameters were compared with these findings pSS...
Background: Sjögren's syndrome (SS) may accompany psoriatic arthritis (PsA), if ever, and its presence during psoriasis (PsO) is rare. Recent observations of an association with predominantly axial forms PsA are intriguing. Whether SS complicates PsO to the same extent not known.Objectives: To investigate prevalence secondary (sSS) in patients PsA, elucidate disease features associated sSS.Methods: In this cross-sectional, retrospective analysis, we sought sicca symptoms a standard...
Background The Coronavirus disease 2019 (COVID-19) has affected more than two hundred million individuals and many risk factors for increased mortality morbidity in COVID-19 have defined. There are studies evaluating the effect of immunosuppressants used inflammatory rheumatic diseases course COVID-19. (1,2) However, fewer data available on patients with Takayasu arteritis (TAK). Objectives In this study, we aimed to evaluate characteristics outcomes TAK Methods A phone survey was conducted...
Background Besides the aorta and its main branches, coronary arterial involvement is also seen at a substantial rate in patients with Takayasu’s arteritis (TAK). Computerized tomography (CT)-angiography, as non-invasive assessment tool, has started to be used instead of conventional angiography evaluation arteries. However limited data available for role TAK patients. Objectives In this study, we aimed assess by CT-angiography or without symptoms compare clinical characteristics involvement....
Abstract Background Biologic agents are widely used in immune mediated inflammatory diseases (IMID). The risk and consequences of hepatitis B reactivation surface antigen (HBsAg) negative phase virus (HBV) exposed patients is not clear. We aim to investigate the rate biologic within HBV infection. Methods identified followed up at gastroenterology, rheumatology dermatology out-patient clinics with a diagnosis IMID from clinical charts. Patients HBsAg positive Anti-HBc IgG were included....