Lampros Fotis
A5025371094- Autoimmune and Inflammatory Disorders Research
- Kawasaki Disease and Coronary Complications
- Inflammasome and immune disorders
- Adolescent and Pediatric Healthcare
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Renal Diseases and Glomerulopathies
- Gastrointestinal disorders and treatments
- Inflammatory Myopathies and Dermatomyositis
- Acute Lymphoblastic Leukemia research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Infectious Diseases and Tuberculosis
- Osteomyelitis and Bone Disorders Research
- Eosinophilic Disorders and Syndromes
- Atherosclerosis and Cardiovascular Diseases
- Orthopedic Infections and Treatments
- Streptococcal Infections and Treatments
- COVID-19 and Mental Health
- Systemic Sclerosis and Related Diseases
- Immunodeficiency and Autoimmune Disorders
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- Apelin-related biomedical research
- Sarcoidosis and Beryllium Toxicity Research
- Rheumatoid Arthritis Research and Therapies
National and Kapodistrian University of Athens
2020-2025
Center for Rheumatology
2024
AHEPA University Hospital
2022-2023
Aristotle University of Thessaloniki
2022-2023
University of Siena
2023
Central Clinical Hospital
2023
Biomedical Research Foundation of the Academy of Athens
2022
Hippocration General Hospital
2022
University General Hospital Attikon
2020-2022
Academy of Athens
2022
COVID-19 pandemic has undoubtedly disrupted the well-established, traditional structure of medical education. Τhe new limitations physical presence have accelerated development an online learning environment, comprising both asynchronous and synchronous distance education, introduction novel ways student assessment. At same time, this prolonged crisis had serious implications on lives students including their psychological well-being impact academic trajectories. The reality has, many...
COVID-19 pandemic has caused a global public health emergency resulting in unprecedented individual and societal fear anxiety. The stress surrounding this biothreat appears to have clinical implications all aspects of medicine, both mental physical spheres. impact related anxiety Cardiology, Paediatrics, Oncology, Dermatology, Neurology Mental Health how it affects treatments is discussed. Moreover, the need for introducing novel communication therapeutic approaches highlighted new landscape era.
Abstract Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe hyperinflammatory condition that may occur following SARS-CoV-2 infection. This retrospective, descriptive study of hospitalized with multisystem 12 tertiary care centers from 3/11/2020 to 12/31/2021. Demographics, clinical and laboratory characteristics, treatment outcomes are described. Among 145 patients (95 males, median age 8.2 years) included, 123 met the WHO criteria for MIS-C, while 112 (77%) had...
Abstract Objectives To assess the lung involvement in patients with Still’s disease, an inflammatory disease assessing both children and adults. exploit possible associated factors for parenchymal these patients. Methods A multicentre observational study was arranged consecutive characterized by among those included AIDA (AutoInflammatory Disease Alliance) Network Registry. disease-lung defined presence of pleuritis, features, acute respiratory distress syndrome (ARDS), and/or pulmonary...
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at crossroads between autoimmunity and autoinflammation. Some patients may even present with autoinflammatory-related manifestations, including fever, hidradenitis suppurativa, other neutrophilic dermatoses, an unusually high increase in inflammatory markers. Therefore, subgroup of SpA be identified, specific details about this cluster need to investigated. In regard, AutoInflammatory Disease Alliance...
The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Registry-based observational study. Children receiving ADA active were divided into group (group 1) plus MTX 2). Eighty four children enrolled (146 eyes): 22 1 (26.2%) 62 2 (73.8%). complete 48 (57.1%), partial 23 (27.4%) absent 4 (5.3%), without any differences across groups (p = 0.89). Fewer relapses per 100 PY occurred...
Still's disease is more frequently observed in the paediatric context, but a delayed onset not exceptional both adulthood and elderly. However, whether paediatric-onset, adult-onset elderly-onset represent expressions of same continuum or different clinical entities still matter controversy. The aim this study to search for any differences demographic, features response treatment between pediatric-onset, disease.Subjects included were drawn from International AutoInflammatory Disease...
Objective We aimed to evaluate the clinical usefulness of systemic score in prediction life‐threatening evolution Still disease. also assess relevance each component predicting and derive patient subsets accordingly. Methods A multicenter, observational, prospective study was designed including patients included Gruppo Italiano Di Ricerca Reumatologia Clinica e Sperimentale Adult‐Onset Disease Study Group Autoinflammatory Alliance Network Registry. Patients were assessed see if variables...
Different patient clusters were preliminarily suggested to dissect the clinical heterogeneity in Still's disease. Thus, we aimed at deriving and validating disease a multicentre, observational, prospective study stratify these patients.Patients included GIRRCS AOSD-study group AIDA Network Still Disease Registry assessed if variables for cluster analysis available (age, systemic score, erythrocyte sedimentation rate (ESR), C reactive protein (CRP) ferritin). K-means algorithm with Euclidean...
Objective. Accumulating evidence links juvenile idiopathic arthritis (JIA) to nonhost factors such as gut microbes. We hypothesize that children with new-onset JIA have increased intestinal bacterial translocation and circulating lipopolysaccharide (LPS). Methods. studied systemic treatment-naive patients [polyarticular JIA, n = 22, oligoarticular 31, spondyloarthropathies (SpA), 16], established inflammatory bowel disease–related (IBD-RA, 11), 34 healthy controls. determined IgG reactivity...
A small percentage of children with Henoch-Schönlein purpura (HSP) develop a chronic form the disease that often requires prolonged corticosteroid therapy. Disease modifying anti-rheumatic agents (DMARDs) or biologics have been successfully used to treat those refractory cases. Azathioprine is DMARD has reported be effective in HSP nephritis and adult cutaneous leukocytoclastic vasculitis, condition histology similar HSP.A description 6 cases relapsing without significant renal involvement,...
In this nationwide retrospective study, a substantial decline in the incidence of multisystem inflammatory syndrome children over 3 successive pandemic waves characterized by different severe acute respiratory coronavirus 2 variants was documented-from 3.4 1000 to 1.1 and finally 0.25 confirmed positive cases (P < 0.0001), respectively, whereas clinical findings severity did not significantly vary.
Objective To develop a standardized steroid dosing regimen (SSR) for physicians treating childhood‐onset systemic lupus erythematosus (SLE) complicated by nephritis (LN), using consensus formation methodology. Methods Parameters influencing corticosteroid (CS) were identified (step 1). Data from children with proliferative LN used to generate patient profiles 2). Physicians rated changes in renal and extrarenal SLE activity between 2 consecutive visits proposed CS 3). The SSR was developed...
Since many biological drug patents have expired, biosimilar agents (BIOs) been developed; however, there are still some reservations in their use, especially childhood. The aim of the current study is to evaluate efficacy and safety tumor necrosis factor (TNF) inhibitors BIOs as treatment for pediatric non-infectious uveitis (NIU).
To describe clinical characteristics of patients with Still's disease treated methotrexate (MTX) and to assess drug effectiveness evaluating change in activity, reduction inflammatory markers, glucocorticoid (GC)-sparing effect.Patients MTX were assessed among those included AIDA Network Still Disease Registry.In this registry, 171 (males 43.3%, age 37.1 ± 16.0 years). They mainly characterised by joint features fever without a prominent multiorgan involvement. was administered GCs 68.4%...
Lung involvement in rheumatic diseases is a major determinant of patient morbidity and mortality; however, its diagnosis depends on the detection methods used. We compared incidence pulmonary newly diagnosed treatment-naive patients with diseases, as assessed by function tests (PFTs) chest high-resolution computed tomography (HRCT). This retrospective study reviewed symptoms, spirometry results, HRCT scans 22 diagnosed, treatment-naïve age-matched controls from University General Hospital...