Amita Aggarwal
A5054123086- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Immunodeficiency and Autoimmune Disorders
- Adolescent and Pediatric Healthcare
- Inflammasome and immune disorders
- Immune Cell Function and Interaction
- Psoriasis: Treatment and Pathogenesis
- Renal Diseases and Glomerulopathies
- Monoclonal and Polyclonal Antibodies Research
- Vasculitis and related conditions
- Inflammatory Myopathies and Dermatomyositis
- T-cell and B-cell Immunology
- Infectious Diseases and Tuberculosis
- Systemic Sclerosis and Related Diseases
- Chronic Lymphocytic Leukemia Research
- Diabetes and associated disorders
- Atherosclerosis and Cardiovascular Diseases
- Tuberculosis Research and Epidemiology
- Acute Lymphoblastic Leukemia research
- Lymphoma Diagnosis and Treatment
- Adrenal Hormones and Disorders
- Pregnancy and Medication Impact
- Mycobacterium research and diagnosis
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2016-2025
Creative Commons
2023
Nizam's Institute of Medical Sciences
2023
Center for Rheumatology
2021
University of Lucknow
2020
Dr. D.Y. Patil Vidyapeeth, Pune
2020
Post University
2020
University Grants Commission
2013
National Institute on Aging
2013
Post Graduate Institute of Medical Education and Research
2012
The human genome is thought to harbor 50,000 100,000 genes, of which about half have been sampled date in the form expressed sequence tags. An international consortium was organized develop and map gene-based tagged site markers on a set two radiation hybrid panels yeast artificial chromosome library. More than 16,000 genes mapped relative framework that contains 1000 polymorphic genetic markers. gene unifies existing physical maps with nucleotide protein databases fashion should speed...
Abstract Introduction Work disability is a major consequence of rheumatoid arthritis (RA), associated not only with traditional disease activity variables, but also more significantly demographic, functional, occupational, and societal variables. Recent reports suggest that the use biologic agents offers potential for reduced work rates, conclusions are based on surrogate measures derived from studies primarily Western countries. Methods The Quantitative Standard Monitoring Patients RA...
To assess the determinants of patients' (PTGL) and physicians' (MDGL) global assessment rheumatoid arthritis (RA) activity factors associated with discordance among them.A total 7,028 patients in Quantitative Standard Monitoring Patients RA study had PTGL MDGL assessed at same clinic visit on a 0-10-cm visual analog scale (VAS). Three patient groups were defined: concordant rating group (PTGL within ±2 cm), higher exceeding by >2 lower less than cm). Multivariable regression analysis was...
Objective To compare the capacity of 2004 diagnostic guidelines for hemophagocytic lymphohistiocytosis (HLH‐2004) with preliminary systemic juvenile idiopathic arthritis (JIA)–associated macrophage activation syndrome (MAS) to discriminate MAS complicating JIA from 2 potentially confusable conditions, represented by active without and infection. Methods International pediatric rheumatologists hemato‐oncologists were asked retrospectively collect clinical information patients JIA–associated...
Abstract Withania somnifera (WS) is an important herb with known antiinflammatory activity. Its molecular mechanism of action has not been investigated. The effect a WS crude ethanol extract was studied on peripheral blood mononuclear cells normal individuals and rheumatoid arthritis (RA) patients synovial fluid RA in vitro. significantly suppressed lipopolysaccharide (LPS) induced production proinflammatory cytokines TNF‐ α , IL‐1 β IL‐12p40 patients, but had no IL‐6 at the protein...
IP-10 and MCP-1 are pro-inflammatory chemokines which involved in the immunopathogenesis of lupus nephritis may thus be useful biomarkers.SLE patients fulfilling ACR 1997 criteria were included. SLEDAI was calculated blood urine samples collected. Active defined as ≥4. divided into active renal (proteinuria ≥ 500 mg/day or sediment urine) non-renal lupus. Patients with followed until became inactive, when a second sample Serum urinary levels (pg/ml) measured by ELISA. Urinary values...
Objective Deficiency of adenosine deaminase 2 (DADA2) is a potentially fatal monogenic syndrome characterized by variable manifestations systemic vasculitis, bone marrow failure, and immunodeficiency. Most cases are diagnosed pediatric care providers, given the typical early age disease onset. This study was undertaken to describe clinical phenotypes treatment response both in adults children with DADA2 India. Methods A retrospective analysis adult patients at various rheumatology centers...
Mendelian Susceptibility to Mycobacterial diseases (MSMD) are a group of innate immune defects with more than 17 genes and 32 clinical phenotypes identified. Defects in the IFN-γ mediated immunity lead an increased susceptibility intracellular pathogens like mycobacteria including attenuated Mycobacterium bovis -Bacillus Calmette-Guérin (BCG) vaccine strains non-tuberculous environmental (NTM), Salmonella , fungi, parasites Leishmania some viruses, otherwise healthy individuals. Mutations...
Severe Combined Immune Deficiency (SCID) is an inherited defect in lymphocyte development and function that results life-threatening opportunistic infections early infancy. Data on SCID from developing countries are scarce.To describe clinical laboratory features of diagnosed at immunology centers across India.A detailed case proforma Excel format was prepared by one the authors (PV) sent to India care for patients with primary immunodeficiency diseases. We collated clinical, laboratory,...
Quality of life (QOL) patients affected by various diseases is now recognized as an important outcome variable. Consenting with rheumatoid arthritis (American College Rheumatology criteria) were included in the study. was assessed using World Health Organization Life assessment, short form (WHOQOL-BREF). Disease activity Activity Score (DAS28) for 3 variables and functional disability Assessment Questionnaire (HAQ). Extra-articular manifestations (ExRA) diagnosed clinically. Seventy-five...
Distance learning may be useful for building health research capacity. However, evidence that it can improve knowledge and skills in research, particularly resource-poor settings, is limited. We compared the impact acceptability of teaching two distinct content areas, Biostatistics Research Ethics, through either on-line distance format or traditional on-site training, a randomized study India. Our objective was to determine whether courses Ethics could achieve similar improvements...