A5023792659- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Adolescent and Pediatric Healthcare
- Musculoskeletal pain and rehabilitation
- Bone and Joint Diseases
- Musculoskeletal Disorders and Rehabilitation
- Psoriasis: Treatment and Pathogenesis
- Musculoskeletal synovial abnormalities and treatments
- Infectious Diseases and Tuberculosis
- Bone health and osteoporosis research
- Orthopedic Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- Healthcare Systems and Practices
- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Bone health and treatments
- Peripheral Neuropathies and Disorders
- Orthopedic Surgery and Rehabilitation
- Spine and Intervertebral Disc Pathology
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Bone Tumor Diagnosis and Treatments
International University of Rabat
2020-2025
Hôpital El Ayachi
2011-2024
Université Mohammed VI des Sciences de la Santé
2017-2024
Centre Hospitalier Ibn Sina
2004-2024
Mohammed V University
2008-2024
Association Marocaine Pour la Recherche Développement
2024
Ibn Sina Hospital
2024
University of Health Science
2024
University of Health Sciences
2024
Center for Rheumatology
2013-2021
Lafora disease (LD) can be diagnosed by skin biopsy, but this approach has both false negatives and positives. Biopsies of other organs also diagnostic are more invasive. Genetic diagnosis is possible inconclusive, for example, in patients with only one heterozygous <i>EPM2A</i> mutation apparently homozygous <i>EPM2B</i> mutations where parent not a carrier the mutation. We sought to identify occult clarify genotypes confirm LD apparent nonrecessive inheritance. used single nucleotide...
To estimate the minimum clinically important improvement (MCII) and patient acceptable symptom state (PASS) values for 4 generic outcomes in 5 rheumatic diseases 7 countries.We conducted a multinational (Australia, France, Italy, Lebanon, Morocco, Spain, The Netherlands) 4-week cohort study involving 1,532 patients who were prescribed nonsteroidal antiinflammatory drugs ankylosing spondylitis, chronic back pain, hand osteoarthritis, hip and/or knee or rheumatoid arthritis. MCII PASS...
Abstract Introduction Work disability is a major consequence of rheumatoid arthritis (RA), associated not only with traditional disease activity variables, but also more significantly demographic, functional, occupational, and societal variables. Recent reports suggest that the use biologic agents offers potential for reduced work rates, conclusions are based on surrogate measures derived from studies primarily Western countries. Methods The Quantitative Standard Monitoring Patients RA...
<h3>Background</h3> Increased risk of some comorbidities has been reported in spondyloarthritis (SpA). Recommendations for detection/management these have proposed, and it is known that a gap exists between their implementation practice. <h3>Objective</h3> To evaluate (1) the prevalence factors different countries worldwide, (2) available recommendations daily practice management (3) previously unknown detected as result present initiative. <h3>Methods</h3> Cross-sectional international...
Objectives To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Methods Cross-sectional study 24 participating countries. Patients a diagnosis of axial SpA (axSpA), (pSpA) or PsA according to their rheumatologist were included. The investigators asked which out list six (axSpA, PsA, pSpA, inflammatory bowel disease-associated SpA, reactive juvenile (Juv-SpA)) fitted patient best. Peripheral...
Introduction: chronic pain in rheumatology often has a psychic impact, which may aggravate the daily life of patients. Chronic neck pain, as an example, is frequent reason for consultation. The aim this study to assess prevalence anxiety and depression patients with identify risk factors associated their occurrence.
The ability to interpret scores from patient-reported outcome measures at the individual patient level depends on availability of valid, clinically meaningful benchmarks response and state attainment. goal was develop multinational estimates for minimal important improvement (MCII) acceptable symptomatic (PASS).A sample patients with osteoarthritis (OA) evaluated before 4 weeks after treatment nonsteroidal antiinflammatory drugs. Patients completed either Western Ontario McMaster...
Spine-related disorders are a leading cause of global disability and burden on society to public health. Currently, there is no comprehensive, evidence-based model care for spine-related disorders, which includes back neck pain, deformity, spine injury, neurological conditions, spinal diseases, pathology, that could be applied in health settings. The purposes this paper propose: (1) principles transform the delivery care; (2) an globally; (3) implementation suggestions. Global Spine Care...
The aims of the present study were first to detect MCID for WOMAC in a Moroccan population, and second, identify best pre-treatment predictors on change health after treatment by non-specific, non-steroidal anti-inflammatory drugs (NSAIDs), evaluate whether dependent choice response criterion. involved 173 patients with osteoarthritis whom primary care physicians decided start non-selective NSAIDs. Assessments at admission 6 weeks conducted. In order determine threshold levels associated...
Abstract Background Some studies have implicated several possible metabolic linkages between osteoporosis and vascular calcification, including estrogen deficiency, vitamin D excess, K deficiency lipid oxidation products. Nevertheless, it remains unclear whether atherosclerosis are related to each other or independent processes, both aging. The aim of this cross-sectional study was evaluate the correlation arterial thickening bone status in a sample apparently healthy Moroccan women. Methods...
The aims of this study are to evaluate vitamin D status in 1413 RA patients COMORA from 15 countries and analyze relationship between patients' characteristics low levels D. All demographic, clinical, biological data comorbidities were completed. results showed that the average serum dosage was 27.3 ng/mL ± 15.1 [0.1-151]. Status insufficient 54.6% deficient 8.5% patients. 43% supplemented with absence supplementation on related higher prevalence deficiency (p < 0.001). Finally, our shows is...
Objective. To establish cutoffs for the minimum clinically important improvement (MCII) and patient-acceptable symptom state (PASS) Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) Functional (BASFI) in patients with ankylosing spondylitis (AS). Methods. Patients AS who started nonsteroidal antiinflammatory drugs were included. After 4 weeks, PASS MCII defined using external anchor questions (for PASS, considering their condition of over prior 48 h as “acceptable” forever; MCII,...
Abstract Background Several factors, in addition to low bone mineral density (BMD), have been identified as risks for fractures, including reduced levels of physical activity, poor balance and performance. The aim this study was evaluate the relationship between performance measures, BMD, falls, risk peripheral fracture a population sample Moroccan women. Methods 484 healthy women were included. Three measures used assess performance: timed get-up-and-go test 'TGUGT', five-times-sit-to-stand...
Abstract Background Metabolic syndrome, a cluster of classical cardiovascular risk factors, including hypertension, obesity, glucose intolerance, and dyslipidemia is highly prevalent in patients with rheumatoid arthritis (RA). The aim the study was to assess frequency metabolic syndrome (MS) RA patients, evaluate relationships between RA. Methods conducted on 120 according 1987 revised American College Rheumatology classification criteria, 100 age sex matched apparently healthy controls....