Luciana Breda
A5077451775- Autoimmune and Inflammatory Disorders Research
- Adolescent and Pediatric Healthcare
- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Ocular Diseases and Behçet’s Syndrome
- Kawasaki Disease and Coronary Complications
- Acute Lymphoblastic Leukemia research
- Immune Cell Function and Interaction
- Immunodeficiency and Autoimmune Disorders
- Family and Disability Support Research
- Orthopedic Infections and Treatments
- Streptococcal Infections and Treatments
- Pericarditis and Cardiac Tamponade
- Childhood Cancer Survivors' Quality of Life
- Lymphoma Diagnosis and Treatment
- Pediatric health and respiratory diseases
- Temporomandibular Joint Disorders
- Otitis Media and Relapsing Polychondritis
- Facial Nerve Paralysis Treatment and Research
- Osteomyelitis and Bone Disorders Research
- Spondyloarthritis Studies and Treatments
- Voice and Speech Disorders
- Musculoskeletal synovial abnormalities and treatments
- Inflammatory Myopathies and Dermatomyositis
University of Chieti-Pescara
2014-2024
Ospedale SS. Annunziata
2022-2023
Ospedale Maggiore
2014-2017
Policlinico Universitario di Catania
2017
Centro Studi GISED
2008
Istituto Giannina Gaslini
2007
Objective. To evaluate safety and efficacy of adalimumab (ADA) infliximab (IFX) for the treatment juvenile idiopathic arthritis-related anterior uveitis (JIA-AU). Methods. Starting January 2007, patients with JIA-AU treated IFX ADA were managed by a standard protocol data entered into National Italian Registry (NIR). At baseline, all refractory to immunosuppressive and/or corticosteroid-dependent. Data recorded every 3 months included course, number/type ocular complications, drug-related...
<h3>Abstract</h3> Antifungal resistance in pathogenic fungi is a growing global health concern. Non-pathogenic laboratory strains of <i>Saccharomyces cerevisiae</i> are useful model for studying mechanisms antifungal that relevant to understanding the same processes fungi. We developed series lab modules which high school students used experimental evolution study by isolating azole-resistant <i>S. and examining genetic basis resistance. All 99 sequenced clones from these experiments...
Objective. To seek insights into the heterogeneity of macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (sJIA) through analysis a large patient sample collected in multinational survey. Methods. International pediatric rheumatologists and hemato-oncologists entered their data, retrospectively, Web-based database. The demographic, clinical, laboratory, histopathologic, therapeutic, outcome data were analyzed relation to (1) geographic location caring...
Our objective was to investigate the pattern of damage accumulation in patients with juvenile-onset systemic lupus erythematosus (JSLE) and relationship between accrual, disease flares cumulative drug therapies. All SLE followed prospectively three tertiary care centres were identified. Only who presented within 12 months diagnosis for at least years included. Damage measures based on chart review using SLICC/ACR index (SDI), which modified (M-SDI) by adding item growth failure....
To assess current treatment in macrophage activation syndrome (MAS) worldwide and to highlight any areas of major heterogeneity practice.
To describe the 6-year safety and efficacy of etanercept (ETN) in children with extended oligoarticular juvenile idiopathic arthritis (eoJIA), enthesitis-related (ERA), psoriatic (PsA) METHODS: Patients who completed 2-year, open-label, phase III CLinical Study In Pediatric Etanercept for Treatment ERA, PsA, Extended Oligoarthritis (CLIPPER) were allowed to enroll its 8-year long-term extension (CLIPPER2). Children received ETN at a once-weekly dose 0.8 mg/kg, up maximum 50 mg/week. Efficacy...
Artificial intelligence (AI) has become a popular tool for clinical and research use in the medical field. The aim of this study was to evaluate accuracy reliability generative AI on pediatric familial Mediterranean fever (FMF). Fifteen questions repeated thrice FMF were prompted Microsoft Copilot with Chat-GPT 4.0. Nine rheumatology experts rated response blinded mechanism using Likert-like scale values from 1 5. Median overall responses at initial assessment ranged 2.00 5.00. During second...
Data from routine clinical practice are needed to further define the efficacy and safety of biologic medications in children with juvenile idiopathic arthritis (JIA). The aim this analysis was investigate disease status, reasons for discontinuation adverse events Italian JIA patients treated etanercept (ETN). In 2013, all centers Pediatric Rheumatology Study Group were asked make a census given ETN after January 2000. Patients classified three groups: group 1 = still taking ETN; 2...