A5060958550- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Acne and Rosacea Treatments and Effects
- Nail Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- melanin and skin pigmentation
- Drug-Induced Adverse Reactions
- Skin Protection and Aging
- Cutaneous lymphoproliferative disorders research
- Genetic and rare skin diseases.
- Powdery Mildew Fungal Diseases
- Urticaria and Related Conditions
- Tuberculosis Research and Epidemiology
- Inflammatory Myopathies and Dermatomyositis
- Infectious Diseases and Tuberculosis
- Dermatological and COVID-19 studies
- Diagnosis and Treatment of Venous Diseases
- Eosinophilic Disorders and Syndromes
- Apelin-related biomedical research
- Phagocytosis and Immune Regulation
- Retinoids in leukemia and cellular processes
Marmara University
2011-2025
Istanbul University-Cerrahpaşa
2009
Istanbul University
2007
Evidence on the effectiveness, long-term safety and longevity of biologic therapies in pediatric psoriasis patients is sparse. This study aims to compares efficacy, drug survival (DS) rates etanercept (ETA), adalimumab (ADA), infliximab (INF), ustekinumab (UST), secukinumab (SEC) ixekizumab (IXE) adult patients. 293 treatment cycles 198 (62 136 adult) from three academic referral centres were analysed. The following Psoriasis Area Severity Index 90 response scores patients, respectively:...
Abstract Background Narrowband UVB phototherapy has been increasingly used in a variety of dermatological diseases. We planned to evaluate its efficacy generalized pruritus this prospective study. Methods Forty‐six patients were included and then divided into two groups: group 1 2 consisted with uremic “idiopathic pruritus”, respectively. Phototherapy was given three times week. Efficacy assessments made by means visual analog scale (VAS) grading score. Results Thirty‐five completed the...
According to some animal data, impairments in learning and memory are seen with isotretinoin. Isotretinoin has been shown affect human brain metabolism, but the data on neural functions is lacking.To evaluate whether isotretinoin treatment affects cognitive functions, causes depression anxiety or alters anger level expression.Neuropsychological tests of attention executive behavioural measuring measures assessing acne severity were applied 63 severe and/or resistant patients from four...
Abstract Objective To investigate the frequency and clinicopathological features of skin involvement in rheumatoid arthritis (RA), to find out whether early aggressive disease‐modifying treatment is changing spectrum towards a milder disease pattern. Methods Two hundred fifteen consecutive RA patients were enrolled. Main outcome measures cutaneous their relation severity modality, ultrasound (USG) examination nodules, histopathological nodules papules. Results Mean age duration 55.3 years...
Abstract Background Tumor necrosis factor‐alpha ( TNF ‐ α ) antagonist treatment is associated with 1.6 to 27 times higher risk of tuberculosis TB ). Objective To find incidence psoriasis patients treated antagonists and define factors related this condition in a country moderately high . Methods Three hundred seventy by anti‐ agents four referral centers were included. The data on the characteristics patients, history, skin test results, agent type exposure time, localization , isoniazide...
Abstract Background/Objectives Psoriasis patients have a higher risk of liver abnormalities such as non‐alcoholic fatty disease ( NAFLD ), drug‐induced hepatitis, alcoholic hepatitis and neutrophilic cholangitis, than the general population. Associated limits therapeutic options necessitates careful monitoring. The aim study was to identify problems in psoriasis investigate underlying causes well their course. Methods files 518 were retrospectively reviewed. Among these, 393 with relevant...
Abstract Background Recently, two placebo‐controlled studies have shown that topical metronidazole was effective in the treatment of seborrheic dermatitis. Objective To compare efficacy and safety 0.75% gel with ketoconazole 2% cream facial Methods A total 60 consecutive patients dermatitis were included. Patients randomized into groups. One group used as vehicle; other vehicle for a 4‐week period. Main outcome measures change clinical severity scores, patients’ investigator's global...
Summary Pigmented purpuric dermatoses are a group of chronic, recurrent disorders characterized by lesions mainly involving the lower extremities. Their etiology is unknown. Treatment options limited and none them have proven benefit. Phototherapy has been reported to be effective in small number patients literature. We present case Schamberg's disease showing dramatic response psoralen plus ultraviolet A therapy discuss current therapeutic focusing on phototherapy. believe that phototherapy...
Phacomatosis pigmentovascularis (PPV) is a group of syndromes comprising coexistent vascular and pigmentary nevi, which first classified into five subtypes then further categorized according to the absence or presence associated systemic findings as type (a) (b), respectively. This case report an 11‐year‐old Turkish girl with extensive nevus spilus. Because scoliosis, patient represents example PPV IIIb. Including present case, total eight cases IIIb have been reported date. The discussed in...
An increased risk for cardiovascular disease with psoriasis has been reported. Growth Arrest-Specific 6 (GAS6) amplifies pro-inflammatory endothelial cell activation via TAM receptors. However, it also inhibits inflammation by multiple mechanisms including phagocytosis. The objective of this study was to investigate whether plasma GAS6 levels are associated conventional cardiometabolic (CM) factors in patients psoriasis.Forty diagnosed (22 male, mean age: 43.3 ± 13.8 years) and 40...
Background: A combination of oral psoralen with narrowband ultraviolet B (UVB), defined as ‘psoralen‐narrowband UVB’, was shown to have a superior efficacy than UVB alone and even comparable in psoriasis. Objective: To find out whether topical psoralen‐narrowband provides any additional benefit Methods: Nineteen patients plaque psoriasis were included. Phototherapy given three times per week. Two symmetrical lesions selected target lesions. In the first 12 sessions phototherapy, lesion on...
Background: The risk of hepatitis B reactivation in surface antigen-negative phase virus-infected patients exposed to biologic agents is not clear.We aimed investigate the rate after therapy.Methods: Patients followed at gastroenterology, rheumatology, and dermatology clinics with a diagnosis immune-mediated inflammatory diseases were screened.Immune-mediated negative antigen positive core immunoglobulin G antibody included study.Results: We screened 8266 disease patients, 2484 identified as...
Background: Erosive pustular dermatosis is a distinctive clinical entity that has been described on either the scalp or legs. Chronic, shallow erosions covered by yellow crusts develop in atrophic fibrotic skin. The most commonly encountered localization, whereas erosive of leg also reported several cases. histopathologic picture nonspecific, and disease usually considered as diagnosis exclusion. Objective Conclusion: We report two patients with who were unresponsive to antibacterial...
The data that support the findings of this study are available from corresponding author upon reasonable request.
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infections can be associated with several cutaneous lesions, among which maculopapular rash is the most common.A also induced by medications used for Coronavirus disease-2019 (COVID-19) treatment.The distinction between viral and drug eruption may difficult especially in case of medication use COVID-19.Thus, this study aimed to describe manifestations six patients COVID-19 highlight clues distinguishing SARS-CoV-2-related...