- Antioxidant Activity and Oxidative Stress
- Bee Products Chemical Analysis
- Sperm and Testicular Function
- Selenium in Biological Systems
- Insect and Pesticide Research
- Liver Disease Diagnosis and Treatment
- Medical and Biological Ozone Research
- Vitamin C and Antioxidants Research
- Animal Nutrition and Physiology
- Pesticide Exposure and Toxicity
- Healthcare and Venom Research
- Chemotherapy-induced organ toxicity mitigation
- Acupuncture Treatment Research Studies
- Birth, Development, and Health
- Drug-Induced Hepatotoxicity and Protection
- Hydrogen's biological and therapeutic effects
- Aquaculture Nutrition and Growth
- Biochemical Acid Research Studies
- Circadian rhythm and melatonin
- Adipose Tissue and Metabolism
- Air Quality and Health Impacts
- Microbial infections and disease research
- Advanced oxidation water treatment
- Biochemical effects in animals
- Amino Acid Enzymes and Metabolism
Fırat University
2015-2024
Marmara University
2023
Trakya University
2021
Elazığ Eğitim ve Araştırma Hastanesi
2012-2019
Eskisehir Technical University
2018
Anadolu University
2017
Eskişehir City Hospital
2017
Hacettepe University
2017
Dicle University
2006
Czech Academy of Sciences
2002
Abstract: In this study, we investigated the effect of melatonin on cisplatin‐induced spermiotoxicity using quantitative, biochemical and histopathological approaches. Cisplatin (CP, 7 mg/kg) (10 were intraperitoneally injected. The rats decapitated 5th (short‐term group) or 50th day (long‐term after CP injection. Traits reproductive organs, sperm characteristics, testicular histological findings, lipid peroxidation in tissue determined. Melatonin mitigated CP‐induced reductions testes,...
To investigate a possible protective role of lycopene on adriamycin (ADR)-induced spermiotoxicity using quantitative, biochemical and histopathological approaches.Experimental study.Firat University Medical School, Experimental Research Centre, Elazig, Turkey.Twenty four Sprague Dawley rats (8-weeks old)Adriamycin (10 mg kg(-1)) was intraperitoneally injected (4 administered by gavage in corn oil.Reproductive organ weights were evaluated along with epididymal sperm concentration, motility...
Free radicals are now well known to damage cellular components. To investigate whether age and thyroid level affect peroxidation speed, we examined the levels of malondialdehyde antioxidant enzyme activities in different groups hypothyroid rats. Hypothyroidism was induced 30- 60-day-old Wistar Albino rats by i.p. administration propylthiouracil (10 mg kg(-1) body weight) for 15 days. While or were increased liver, they decreased tissues heart thyroid. glucose-6-phosphate dehydrogenase...
In this study, we investigated the antioxidant activity of ethanol extracts propolis (EEP) and vitamin C on biochemical indicators enzyme activities broilers exposed to heat stress (at 34 °C). The experimental groups were as follows: group I (positive control) II (control) fed a basal diet, III (vitamin C) was diet supplemented with 250 mg ascorbic acid/kg, IV (EEP-0.5) 0.5 g EEP/kg, V (EEP-1) 1 VI (EEP-3) 3 EEP/kg. Plasma superoxide dismutase levels positive control, C, EEP-0.5, EEP-1 EEP-3...
The aim of this study was to investigate the possible protective role antioxidant treatment with lycopene on cyclosporine A-induced nephrotoxicity using biochemical and histopatological approaches. Adult male Sprague-Dawley rats were randomly divided into four groups. control group received physiological saline; animals in only (10 mg/kg); A (15 mg/kg) plus for 21 days. effects evaluated by plasma creatinine, urea, sodium calcium concentrations; kidney tissue thiobarbituric acid reactive...
Lipid peroxidation is the most important mechanism in pathogenesis of acute liver damage with carbon tetrachloride (CCl4). L-carnitine may prevent lipid and thus protect against damage. In present study we investigated protective effect experimental induced by CCl4.Fifty rats were allocated to five equal groups. The first group was control (group 1), second received an intraperitoneal CCl4 injection for 3 days 2), third a 50 mg/kg subcutaneous 4 days, beginning day before injection....
Background. Aflatoxins are toxic metabolites produced by Aspergillus flavus and parasiticus classified as group I carcinogens the International Agency for Research on Cancer (IARC).Objectives. The purpose of this study was to investigate possible preventive role vitamin E (Vit E) aflatoxin (AF) induced toxicity using biochemical histopathological approaches.Material Methods. Wistar-Albino rats were divided into 4 groups follows: control group, Vit administered), AFB1 (a single dose AF + (AF...
Oxidative damage caused by aflatoxin (AF) in rat liver tissue and the inhibition effect of lycopene against this injury was investigated. Groups were formed as; control group (not treated), (5 mg/kg/day, gavage for 15 days), AFB1 (0.5 7 days) + group. Lycopene administered simultaneously with AFB1. It observed significant increase malondialdehyde level, decrease glutathione antioxidant enzyme activities when compared determined to significantly plasma aspartate transaminase, alanine lactate...
The present study was conducted to investigate the possible protective effects of lycopene (LP) and ellagic acid (EA) on aroclor (AR) 1254-induced testicular spermatozoal toxicity associated with oxidative stress apoptosis in male rats. control group treated placebo. LP (10 mg/kg/every other day), EA (2 day) AR mg/kg/day) groups were given alone LP, respectively. One last two received + EA. Body reproductive organ weights, epididymal sperm characteristics, tissue lipid peroxidation levels,...
Abstract Introduction The aim of this study was to evaluate potential protective effects propolis on furan-induced hepatic damage by assessing the levels malondialdehyde (MDA) and reduced glutathione (GSH), antioxidant enzyme activities, histopathological changes in liver. Material Methods Albino Wistar rats were divided into six groups: a control, propolis-treated (100 mg/kg b.w./day), low-dose furan-treated (furan-L group; 2 high-dose (furan-H 16 furan-L+propolis treated, furan-H+propolis...
Introduction: The study determined the damage caused by formaldehyde (FA) exposure in blood and liver samples using biochemical markers. Histopathological analysis was performed terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) method measurement of CD68 cell density. To what extent antioxidant molecules thymoquinone (TQ) ozone (O3) reversed FA investigated, both when used alone combined. Methods: Fifty-six Sprague-Dawley male rats eight to ten weeks age were experiment....
This study aimed to identify bacterial pathogens in milk samples from dairy cows with subclinical and clinical mastitis as well assess the concentrations of oxidant-antioxidant parameters [malondialdehyde (MDA), reduced glutathione (GSH), total GSH levels] both blood samples. From a 200 8 farms, 800 quarter obtained each udder were tested laboratory for presence pathogens. Cultivated bacteria causing intramammary infection identified by Matrix-Assisted Laser Desorption/Ionization-Time Flight...