Roberta Loconte
A5023694297- Inflammasome and immune disorders
- Immune Cell Function and Interaction
- Travel-related health issues
- interferon and immune responses
- Autoimmune and Inflammatory Disorders Research
- Ferroptosis and cancer prognosis
- Genital Health and Disease
- Streptococcal Infections and Treatments
- IL-33, ST2, and ILC Pathways
Ospedale Pediatrico Giovanni XXIII
2023-2025
University of Bari Aldo Moro
2023-2024
Background/Objectives: Chronic non-bacterial osteomyelitis (CNO) is a rare autoinflammatory disease characterized by chronic sterile uni- or multifocal osteomyelitis. The treatment of CNO mostly empirical and the outcome has not yet been standardized. aims this study were to correlate clinically active lesions with radiological signs inflammation evaluate outcomes in terms symptoms Whole Body Magnetic Resonance Imaging (WB-MRI) based on line used. Methods: A retrospective, observational...
To evaluate the potential role of Streptococcus salivarius K12 (SSK12) in controlling febrile flares patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Further aims were to assess impact SSK12 on (i) flare duration, (ii) variation degree highest body temperature during flares, (iii) steroid-sparing effect, (iv) change PFAPA accompanying symptoms before after introduction.The medical charts from 85 pediatric syndrome (49 males 36 females)...
Objective Inflammation has been associated with an increased risk for cancer development, while innate immune system activation could counteract the malignancies. Familial Mediterranean fever (FMF) is a severe systemic inflammatory condition and also represents archetype of immunity deregulation. Therefore, aim this study to investigate development in FMF. Methods The ratio (RR) malignancies was separately compared between FMF patients fibromyalgia subjects, Still’s disease Behçet’s...
The effectiveness of canakinumab may change according to the different times it is used after Still's disease onset. This study aimed investigate whether (CAN) shows differences in short- and long-term therapeutic outcomes, its use as lines biologic treatment.Patients included this were retrospectively enrolled from AutoInflammatory Disease Alliance (AIDA) International Registry dedicated disease. Seventy-seven (51 females 26 males) patients with present study. In total, 39 (50.6%) underwent...