A5048749396- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Adolescent and Pediatric Healthcare
- interferon and immune responses
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Vasculitis and related conditions
- Urticaria and Related Conditions
- Renal Diseases and Glomerulopathies
- Kawasaki Disease and Coronary Complications
- Immunodeficiency and Autoimmune Disorders
- Acute Lymphoblastic Leukemia research
- Health Literacy and Information Accessibility
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Social Media in Health Education
- Genetic and rare skin diseases.
- Salivary Gland Disorders and Functions
- Vascular Malformations and Hemangiomas
- Inflammation biomarkers and pathways
- Heterotopic Ossification and Related Conditions
- Dermatological and Skeletal Disorders
- Travel-related health issues
- Celiac Disease Research and Management
- Systemic Lupus Erythematosus Research
- Educational Assessment and Pedagogy
University of Chieti-Pescara
2021-2025
Ospedale SS. Annunziata
2024
RELX Group (United States)
2019
University of L'Aquila
2019
The activation of the pyrin inflammasome represents a highly intriguing mechanism employed by innate immune system to effectively counteract pathogenic agents. Despite its key role in immunity, has also garnered significant attention due association with range autoinflammatory diseases (AIDs) including familial Mediterranean fever caused disruption MEFV gene, or other genes involved complex regulation mechanisms. Pyrin is strictly dependent on homeostasis-altering molecular processes, mostly...
Designing good multiple choice questions (MCQs) for education and assessment is time consuming error-prone. An abundance of structured semi-structured data has led to the development automatic MCQ generation methods. Recently, ontologies have emerged as powerful tools enable MCQs. However, current question approaches focus on knowledge recall questions. In addition, that so far been generated are, compared manually created ones, simple cover only a small subset required complexity space in...
Abstract Background Hypophosphatasia (HPP) is a rare inherited disorder characterized by deficiency of tissue-non-specific alkaline phosphatase (TNSALP) due to loss-of-function variants the ALPL gene. HPP an extremely variable age onset and clinical presentation, largely depending on type genetic disruption. Childhood commonly presents with skeletal deformities, bone fragility, precocious tooth loss, muscle weakness sometimes neurological implications. Laboratory tests usually document low...
Abstract Introduction Recent works in the scientific literature reported role of C reactive protein to albumin ratio (CAR), neutrophil lymphocyte (NLR) and platelet (PLR) as biomarkers disease activity rheumatic diseases. Objectives To investigate CAR, PLR NLR potential markers children with non-systemic JIA (nsJIA) their correlation risk persistent flare during follow up. Methods Our prospective, cross-sectional study involved 130 nsJIA patients (74 active 56 inactive according Wallace...
Serum calprotectin (MRP8/14) is currently being studied as a promising biomarker of disease activity and outcome in patients with juvenile idiopathic arthritis (JIA) but the data literature are conflicting. The aim our study was to investigate potential role serum flare/remission group nsJIA during follow-up period 18 months. In this prospective longitudinal study, two groups ns-JIA (55 active 56 remission according Wallace's criteria) control (50 children) were recruited at baseline from...
A retrospective study was conducted in order to investigate and describe the characteristics of Immunoglobulin vasculitis (IgAV), previously known as Henoch-Schӧnlein purpura, paediatric population a community-based healthcare delivery system Italian region Abruzzo.This is population-based chart review diagnosis IgAV children ages 0 18, admitted Department Paediatrics Chieti Pescara between 1 January 2000 31 December 2016. All enrolled presented with clinical symptoms laboratory findings met...
Abstract Background Circumferential skin creases is a rare and heterogeneous disorder characterized by multiple redundant folds, which can present as an isolated feature or in association with other phenotypic anomalies. Here, we report the case of newborn who immediately captured our attention because his phenotype. Case A male Caucasian infant was born at 39 weeks 4 days gestational age instrumental delivery, after pregnancy threat preterm birth 32 weeks. Fetal ultrasounds were reported to...