A5010417948- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Pesticide Exposure and Toxicity
- Allergic Rhinitis and Sensitization
- Indoor Air Quality and Microbial Exposure
- Dermatology and Skin Diseases
- Research in Social Sciences
- Food Allergy and Anaphylaxis Research
- Nail Diseases and Treatments
- Chemical Safety and Risk Management
- Advancements in Transdermal Drug Delivery
- Neonatal skin health care
- Immunotoxicology and immune responses
- Surgical Sutures and Adhesives
- Antimicrobial agents and applications
- Asthma and respiratory diseases
- Effects and risks of endocrine disrupting chemicals
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Drug-Induced Adverse Reactions
- Mechanical Behavior of Composites
- Safety Warnings and Signage
- Synthesis and properties of polymers
- Occupational and environmental lung diseases
- Agricultural safety and regulations
- Polymer composites and self-healing
Finnish Institute of Occupational Health
2015-2024
Helsinki University Hospital
1993-2003
Turku University of Applied Sciences
2001
Lappeenranta-Lahti University of Technology
2001
Kuopio University Hospital
2001
University of Helsinki
1992
Summary The present guideline summarizes all aspects of patch testing for the diagnosis contact allergy in patients suspected suffering, or having been from allergic dermatitis other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions discussions different pertinent topics are followed by a highlighted short practical recommendation. Topics comprise, after an introduction important definitions, materials, technique, modifications epicutaneous testing,...
Methacrylates are important allergens in dentistry.The study aimed to analyse patch test reactivity 36 acrylic monomers dental personnel relation exposure.We reviewed the files at Finnish Institute of Occupational Health from 1994 2006 for allergic reactions and analysed clinical records sensitized patients.32 patients had monomers: 15 nurses, 9 dentists, 8 technicians. The dentists nurses were most commonly exposed 2-hydroxyethyl methacrylate (2-HEMA), triethyleneglycol dimethacrylate...
Summary Background Allergic contact dermatitis (ACD) caused by nail acrylates, also including methacrylates and cyanoacrylates here, is being increasingly reported. Methods A retrospective study in 11 European Environmental Contact Dermatitis Research Group (EECDRG) clinics collected information on cases of ACD acrylates diagnosed aimed testing between 2013 2015. Results Among 18 228 studied patients, 136 had (0.75%; 95%CI: 0.60–0.90), representing 67.3% (95%CI: 60.4–73.7) acrylates. There...
Background: Formaldehyde allergy is common and usually derives from formaldehyde‐releasing biocides in cosmetic other products. Objectives: To analyse patterns of patch test reactions to formaldehyde compounds the sources sensitization. Patients/Methods: At Finnish Institute Occupational Health, we screened files for allergic 12 compounds. All patients with contact any substances were included, their records reviewed. Results: Between January 2001 May 2007, had tested 81 18 independent some...
Long-term follow-up studies on the prognosis and consequences of occupational hand eczema (OHE) prognostic risk factors for persistent OHE are sparse.To determine medical outcome after a 7-14 years in 605 patients diagnosed with to identify continuation eczema.Patients examined at Finnish Institute Occupational Health 1994-2001 completed questionnaire diagnosis.The had healed (no during last year) 40% OHE. The duration before diagnosis was strongly associated eczema. Age, sex (allergic or...
Abstract Background Classification of hand eczema ( HE ) is mandatory in epidemiological and clinical studies, also important work. Objectives The aim was to test a recently proposed classification system practice prospective multicentre study. Methods Patients were recruited from nine different tertiary referral centres. All patients underwent examination by specialists dermatology checked using relevant allergy testing. classified into one the six diagnostic subgroups : allergic contact...
The use of methylisothiazolinone (MI) in cosmetic products has caused an unprecedented epidemic MI contact allergy. Current data concerning exposures at a European level are required.To describe demographics and for patients with allergy.Eleven dermatology departments from eight countries prospectively collected between 1 May 31 October 2015 among consecutive who had positive patch test reactions to (2000 ppm aq.).A total 6.0% (205/3434; range 2.6-13.0%) MI. Dermatitis most frequently...
Summary Background Epoxy products are among the most common causes of occupational allergic contact dermatitis. Diglycidyl ether bisphenol A resin ( DGEBA‐R ) is important sensitizer in epoxy systems. Objectives To describe patients with dermatitis caused by products. Methods Patients reactions to chemicals were chosen from test files J anuary 1991 une 2014). Only allergy some component systems included. We analysed patch results, occupation, symptoms, and exposure data. Results found a...
Work-related skin diseases (WSD) are caused or worsened by a professional activity. Occupational (OSD) need to fulfil additional legal criteria which differ from country country. OSD range amongst the five most frequently notified occupational (musculoskeletal diseases, neurologic lung of sensory organs, diseases) in Europe.To retrieve information and compare current state national frameworks pathways manage patients with disease regard prevention, diagnosis, treatment rehabilitation...
Abstract Background Methylisothiazolinone (MI) has caused an unprecedented epidemic of contact allergy in Europe and elsewhere. Subsequently, regulatory action been taken, at least Europe, aiming reducing risk MI sensitization. Objective To follow‐up on the prevalence to consecutively patch tested patients assess spectrum products containing or methylchloroisothiazolinone (MCI)/MI positive which elicited current allergic dermatitis. Methods A cross‐sectional survey was performed 2016 2017,...
Significance Contact dermatitis is an inflammatory skin disorder that arises from direct contact with irritants or allergens. Representing over 90% of occupational disorders, it has a considerable socioeconomic impact, and patients suffering can develop notable physical handicap. Current diagnostic regimes rely on allergy testing, exposure specification, follow-up visits. However, distinguishing the clinical phenotype irritant allergic dermatitis, which important for appropriate therapeutic...
Background: Benzisothiazolinone is used as a slimicide in the manufacture of disposable powder‐free polyvinyl chloride (PVC) gloves. We recently reported 6 patients from dentistry and health care probably sensitized to benzisothiazolinone PVC Objective: The study aimed investigate how widely gloves for medical use on Finnish market 2006 contain report new cases 2 clinics Helsinki. Methods: 31 brands were analysed their content. looked through patient material Helsinki University Central...
To investigate the incidences and trends of occupational skin diseases (OSDs) allergic respiratory (ARDs) in machinists working fabrication metal products.Data from Finnish Register Occupational Diseases during 1992-2001 were analysed. Incidence rates for calculated compared to total population. The patients investigated at Institute Health same period described detail.A 279 dermatoses 34 ARDs reported. Skin accounted 27% all diseases. 1.6 0.2 cases per 1000 person-years, respectively. This...
Acrylic resin monomers, especially acrylates and methacrylates, are important occupational allergens.To analyse patterns of concomitant patch test reactions to acrylic monomers in relation exposure, suggest possible screening allergens.We reviewed the files for years 1994-2009 at Finnish Institute Occupational Health allergic analysed clinical records sensitized patients.In a group 66 patients an monomer, most commonly positive allergens were three namely ethyleneglycol dimethacrylate...
Background. Antimicrobials constitute the second most common cause of contact allergy to cosmetics. Methylisothiazolinone (MI), previously always used together with methylchloroisothiazolinone (MCI), has recently been approved in EU for use on its own cosmetics and also various industrial products. MCI classified as an extreme–strong MI a strong–moderate sensitizer. Objectives. To study frequency positive patch test reactions MI, relevance relation MCI/MI sensitivity, Finland. Methods. Over...
Background: Glues and sealants are important causes of methacrylate acrylate allergy. Aim: This study aimed to analyse patterns allergic patch test reactions acrylic monomers in relation exposure patients sensitized from glues. Patients/Methods: We screened the files at Finnish Institute Occupational Health 1994 2006 for ‘Methacrylate series’ analysed clinical records patients. Only who had handled glues work were included. Results: 10 been work. 9 them used anaerobic sealants, 3...
Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these has been considered rare.We describe 21 patients diagnosed with occupational at the Finnish Institute Occupational Health during period 1990-2006.Prick test human serum albumin (HSA)-acid anhydride conjugates, determination specific immunoglobulin E (IgE), and open application were used in diagnosis.The majority worked manufacture electrical machines exposed to an epoxy hardener...
The monomeric isocyanates diphenylmethane diisocyanate (MDI), 2,4-toluene (TDI), isophorone (IPDI) and 1,6-hexamethylene (HDI) are used in polyurethane products sometimes cause contact allergy.To describe patients with isocyanate allergy an occupational dermatology clinic.Test files were screened for allergic reactions to 4,4'-diaminodiphenylmethane (MDA). Patients some of the allergens analysed occupation, exposure, concomitant other allergens, diagnosis.Over a period almost 13 years, 54...
Summary Background Little is known about the use of prick tests with chemicals in diagnosing occupational diseases. Objective To evaluate diagnosis contact urticaria, asthma and rhinitis caused by (undertaken at F innish I nstitute O ccupational H ealth). Material methods We retrospectively reviewed patient test files for period 1 J anuary 1991 to 31 M ay 2011. Prick were performed chemical solutions human serum albumin ( HSA )–chemical conjugates. Results Positive reactions isocyanate–...
Limonene is widely used as a fragrance substance and solvent in cleansing products. Oxidized limonene frequent contact allergen among consumers of cosmetics, personal care products, scented household cleaning Less known about the sources occupational exposure dermatitis caused by limonene.To report 14 patients with allergy to limonene.The were examined 2008-2013. An in-house preparation oxidized was patch tested 3% 5% petrolatum from 2008 August 2010, after this 3%, 1% 0.3% pet. From 2012...
Summary Background Contact urticaria ( CU ) and protein contact dermatitis PCD are mainly induced by an immediate, I g E ‐mediated immunological mechanism. Immediate sensitization is also linked to asthma and/or allergic rhinitis. Objectives To report causes of work‐induced PCD, evaluate the occurrence concomitant airway diseases. Methods We retrospectively reviewed patient files cases diagnosed with or at F innish nstitute O ccupational H ealth during 1995–2011. obtained data on occupation,...