Andrea Bauer
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Occupational exposure and asthma
- Urticaria and Related Conditions
- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Pesticide Exposure and Toxicity
- Skin Protection and Aging
- Mast cells and histamine
- Drug-Induced Adverse Reactions
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Animal testing and alternatives
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Medical Practices and Rehabilitation
- Immunotoxicology and immune responses
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medical and Health Sciences Research
- Cancer and Skin Lesions
- Indoor Air Quality and Microbial Exposure
- Complementary and Alternative Medicine Studies
University Hospital Carl Gustav Carus
2015-2024
TU Dresden
2015-2024
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2015-2024
Universität Hamburg
2011-2023
Oxfam
2023
Liechtenstein Institute
2023
John Wiley & Sons (United States)
2023
John Wiley & Sons (United Kingdom)
2023
Hudson Institute
2023
Bauer Research Foundation
2023
As robots are gradually leaving highly structured factory environments and moving into human populated environments, they need to possess more complex cognitive abilities. They do not only have operate efficiently safely in natural, but also be able achieve higher levels of cooperation communication with humans. Human–robot collaboration (HRC) is a research field wide range applications, future scenarios, potentially high economic impact. HRC an interdisciplinary area comprising classical...
In the majority of patients with chronic spontaneous urticaria, most currently available therapies do not result in complete symptom control. Ligelizumab is a next-generation high-affinity humanized monoclonal anti-IgE antibody. Data are limited regarding dose-response relationship ligelizumab and efficacy safety as compared omalizumab placebo who have moderate-to-severe urticaria that inadequately controlled H1-antihistamines at approved or increased doses, alone combination...
Abstract Background Preventive measures to decrease the frequency and intensity of anaphylactic events are essential provide optimal care for allergic patients. Aggravating factors may trigger or increase severity anaphylaxis therefore need be recognized avoided. Objective To identify prioritize associated with an increased risk developing severe anaphylaxis. Methods Data from Anaphylaxis Registry (122 centers in 11 European countries) were used logistic regression models considering...
Hand eczema is a common inflammatory skin disorder. Health care providers need continuously updated information about the management of hand to ensure best treatment for their patients.To update European Society Contact Dermatitis guideline on diagnosis, prevention, and eczema.The Guideline Development Group (GDG) was established behalf ESCD. A call interest launched via ESCD website members' mailing list. Appraisal evidence therapeutic preventive interventions applied structured method...
Thymic epithelial tumors (TET) are rare neoplasms of the thymus with considerable histologic heterogeneity. This retrospective study focused on correlation WHO-defined TET histotypes survival and tumor recurrence in a large cohort patients receiving different modes treatment.Two hundred twenty-eight were followed for up to 21 years (median, 60 months; range, 1 252 months) after primary surgery. Forty-two received adjuvant radiotherapy (mean dose, 53 Gy), 33 chemotherapy.Seventy-six (88%) 86...
Summary Background Occupational contact dermatitis is one of the most common occupational diseases in E urope. In order to develop effective preventive measures, detailed and up‐to‐date data on incidence, main causes professions at risk are needed. Objectives To describe pattern patch test reactivity allergens uropean baseline series patients with different occupations. Methods We analysed collected by S urveillance ystem C ontact A llergy ( ESSCA ) network from 2002 2010, 11 countries....
Background. The pattern of contact sensitization to the supposedly most important allergens assembled in baseline series differs between countries, presumably at least partly because exposure differences. Objectives. To describe prevalence tested consecutive patients years 2007 and 2008, discuss possible Methods. Data from 39 departments 11 European countries comprising Surveillance System on Contact Allergy network ( www.essca‐dc.org ) this period have been pooled analysed according common...
Background.Treatment with omalizumab, a humanized recombinant monoclonal anti-IgE antibody, results in clinical efficacy patients Chronic Spontaneous Urticaria (CSU).The mechanism of action omalizumab CSU has not been elucidated detail. Objectives.To determine the effects on levels high affinity IgE receptor-positive (FcεRI + ) and IgE-positive (IgE dermal cells blood basophils.Treatment safety were also assessed.Study design.In double-blind study, aged 18-75 years randomized to receive 300...
Skin diseases constitute up to 40% of all notified occupational in most European countries, predominantly comprising contact dermatitis, urticaria, and skin cancer. While insufficient prevention work-related (WRSD) is a top-priority problem Europe, common standards for these conditions are lacking.To develop on management WRSD (OSD).Consensus amongst experts within dermatology was achieved with regard the definition minimum evidence-based WRSD/OSD.By definition, WRSDs/OSDs (partially or...
The preservative methylisothiazolinone (MI) has become an important allergen, with a dramatic increase in sensitization prevalence being seen over the last few years.To examine risk factors associated MI sensitization, order to identify targets of prevention aimed at curtailing present epidemic.On basis contact allergy surveillance data collected by Information Network Departments Dermatology (www.ivkd.org), 2009-2012, course 28,922 patch tests MI, 500 ppm water, included series cosmetic...
Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, products formulations regulatory intervention, the spectrum contact sensitization changes.To evaluate current allergens present European baseline series (EBS) across Europe.Retrospective analysis data collected by Surveillance System on Allergies (ESSCA, www.essca-dc.org) consecutively patch-tested patients, 2013/14,...
Most data on chronic spontaneous urticaria (CSU) originate from highly selected patient populations treated at specialized centres. Little is known about CSU characteristics and the burden of in routine clinical practice. AWARE (A World-wide Antihistamine-Refractory Evaluation) an ongoing global study designed to assess real-life setting.To describe baseline first 1539 German patients with H1-antihistamine-refractory CSU.This prospective non-interventional included (18-75 years) a diagnosis...
Summary Epicutaneous patch testing is the diagnostic standard for detection of allergic contact dermatitis. The present guidelines are aimed at residents and board‐certified physicians in fields dermatology allergology as well other medical specialties involved establishing indication its execution patients with dermatitis forms delayed‐type hypersensitivity. target audience also includes health care providers insurance funds. Based on a systematic literature search formal consensus process...
Management of chronic hand eczema (CHE) remains a challenge; effective topical treatment is limited to corticosteroids.To assess the efficacy and safety novel, pan-Janus kinase inhibitor (delgocitinib) in patients with CHE.In this randomized, double-blind, phase IIa study, CHE received delgocitinib ointment 30 mg g-1 or vehicle for 8 weeks. The primary end point was proportion achieving success ['clear'/'almost clear' skin ≥ 2-point improvement Physician's Global Assessment disease severity...
Summary Actinic keratoses (AK) are common lesions in light‐skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence‐based framework for clinical decision making, guideline “actinic keratosis carcinoma” was developed using highest level of methodology (S3) according regulations issued by Association...
The COVID-19 pandemic dramatically disrupts health care around the globe. impact of on chronic urticaria (CU) and its management are largely unknown.To understand how CU patients affected by pandemic; specialists alter patient management; course in with COVID-19.Our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed consultations, remote treatment, changes medications, clinical consequences.The severely impairs care, less than 50% weekly numbers...
Summary Basal cell carcinoma (BCC) is the most common malignant tumor among fair‐skinned individuals, and its incidence had been steadily rising in past decades. In order to maintain highest quality of patient care possible, German S2k guidelines were updated following a systematic literature search with participation all professional societies associations involved management disease. Part 2 addresses issues such as proper risk stratification, various therapeutic approaches, prevention well...
Summary Two employees of the National Health Service (NHS) in England developed severe allergic reactions following administration BNT162b2 vaccine against COVID-19 (coronavirus disease 2019). The British SmPC for already includes reference to a contraindication use individuals who have had an reaction or any its components. As precautionary measure, Medicines and Healthcare products Regulatory Agency (MHRA) has issued interim guidance NHS not vaccinate principle “patients with allergies”....
Background Chronic hand eczema (CHE) is a burdensome disease, and new well-documented, safe efficacious treatments are warranted. In recent CHE phase IIa trial, the pan-Janus kinase (JAK) inhibitor delgocitinib in an ointment formulation was found to be well tolerated. Objectives This trial assessed dose response, efficacy safety of cream CHE. Methods this double-blind, IIb dose-ranging adults with history inadequate response or contraindication topical corticosteroids were randomized 1, 3,...
Continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing value included allergens.To present current EBS testing, obtained in 53 departments 13 countries during 2019 2020.Anonymised or pseudonymised individual data partly aggregated on demographic/clinical characteristics rest were prospectively collected centrally pooled analysed.In 2020, 22 581 patients tested EBS. Sensitization to nickel remained most common...