A5074709662- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Occupational exposure and asthma
- Allergic Rhinitis and Sensitization
- Pesticide Exposure and Toxicity
- Drug-Induced Adverse Reactions
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Canadian Identity and History
- Food Allergy and Anaphylaxis Research
- Cutaneous Melanoma Detection and Management
- Medicine and Dermatology Studies History
- Animal testing and alternatives
- Dermatological diseases and infestations
- Skin Protection and Aging
- Eosinophilic Disorders and Syndromes
- Urticaria and Related Conditions
- Cutaneous lymphoproliferative disorders research
- Immunotoxicology and immune responses
- Acne and Rosacea Treatments and Effects
- Autoimmune and Inflammatory Disorders
- Synthesis and properties of polymers
- melanin and skin pigmentation
- Chemical Safety and Risk Management
- Infection Control in Healthcare
University of Waterloo
1996-2020
Nottingham University Hospitals NHS Trust
2009-2019
University of Nottingham
2002-2019
Queen's Medical Centre
2004-2018
Nottingham Biomedical Research Centre
2018
St. Luke's Hospital
2017
University of Warwick
2016
London Road Community Hospital
2016
National Health Service
1996-2013
University Hospitals of Leicester NHS Trust
2007-2011
Examination of 180 patients with cutaneous malignant melanoma and 197 control in a case-control study showed that the risk is strongly related to numbers benign melanocytic naevi (moles). Some unusual features naevi--a diameter exceeding 7 mm, colour variation, irregular lateral outline--also strong association melanoma, but relation was present even group whose had none these features. Biopsy clinically atypical from several at highest generally did not show dysplastic histology. Thus...
Total body mole counts have been performed on 432 normal healthy Caucasian subjects aged 4 days to 96 years (204 males and 228 females). The mean total count in the first decade of life is three for females two males, rising rapidly second a 23 18 males. In third numbers are highest, with 33 22 Thereafter, moles slowly drop until eighth they fallen levels similar those seen pre-pubertal children. There significant association between presence naevi early childhood (prior 5 age) development...
Summary These guidelines have been prepared by the Standards of Care Committee (SOCC) British Society for Allergy and Clinical Immunology (BSACI) are intended allergists others with a special interest in allergy. As routine or validated tests not available majority drugs, considerable experience is required investigation allergic drug reactions to undertake specific challenge. A missed incorrect diagnosis allergy can serious consequences. Therefore, management best carried out specialist...
Background: Continual surveillance based on patch test results has proved useful for the identification of contact allergy. Objectives: To provide a current view spectrum allergy to important sensitizers across Europe. Patients/Methods: Clinical and data 19 793 patients tested in 2005/2006 31 participating departments from 10 European countries (the Surveillance System Contact Allergies' (ESSCA) www.essca‐dc.org ) were descriptively analysed, aggregated four regions. Results: Nickel sulfate...
These guidelines for management of contact dermatitis have been prepared dermatologists on behalf the British Association Dermatologists. They present evidence-based guidance investigation and treatment, with identification strength evidence available at time preparation guidelines, including details relevant epidemiological aspects, diagnosis investigation.
Cellulitis of the leg is a common bacterial infection skin and underlying tissue. We compared prophylactic low-dose penicillin with placebo for prevention recurrent cellulitis.
Background. The pattern of contact sensitization to the supposedly most important allergens assembled in baseline series differs between countries, presumably at least partly because exposure differences. Objectives. To describe prevalence tested consecutive patients years 2007 and 2008, discuss possible Methods. Data from 39 departments 11 European countries comprising Surveillance System on Contact Allergy network ( www.essca‐dc.org ) this period have been pooled analysed according common...
A prospective, open, multicentre study was performed to investigate the efficacy and safety of long-term treatment with cyclosporin in adults severe atopic dermatitis. Subjects were treated for a maximum 48 weeks. For first 8 weeks, administered at 2.5 mg/kg per day. The dose then adjusted according response. Disease activity monitored using six-area, six-sign score proportion skin involved. Pruritus sleep disturbance assessed four-point scales. Response further evaluated on five-point...
Background Photoallergic contact dermatitis can be difficult to diagnose if not appropriately investigated. Currently, the most common U.K. photoallergens appear sunscreen chemicals. The investigation of choice is photopatch testing (PPT), which probably underused. In part, this due differences in methodology and results interpretation. Objectives To conduct PPT using a group chemicals, defined indications standardized including interpretation relevance reactions patients attending for at 17...
The guidelines aim to provide advice on the management of hand eczema (HE), using an evidence- and consensus-based approach. consider a systematic Cochrane review interventions for HE, which is based search published literature (including hand-searching). In addition recommendation treatment cover mainly diagnostic aspects preventive measures (primary secondary prevention). Treatment recommendations include non-pharmacological interventions, topical, physical systemic treatments. Topical...
These guidelines for the management of contact dermatitis have been prepared dermatologists on behalf British Association Dermatologists. They present evidence-based guidance treatment, with identification strength evidence available at time preparation guidelines, including details relevant epidemiological aspects, diagnosis and investigation.
Erythema elevatum diutinum is a syndrome of vasculitis in which lesions, typically over the extensor surfaces, showed mixed inflammatory infiltrate on biopsy. We describe series 13 patients. The most common association our was with hypergammaglobulinemia; both mono and polyclonal. Chronic infection, not streptococcal, less frequent finding although two three patients had positive reaction to intradermal injection streptococcal antigen. Dapsone remains initial treatment choice.
The patients sensitised to sunscreen agents who attended our Contact Dermatitis Clinic between February 1985 March 1987 have been reviewed. 15 (5%) of 280 tested with sunscreens had positive reactions; 3 them were allergic more than one agent. most frequent contact allergens hydroxy methoxy methyl benzophenone (Mexenone) [6], followed by isopropyl dibenzoylmethane (Eusolex 8020/8021) [5], octyl dimethyl para-aminobenzoate (Escalol 507) [2], and reaction each butyl (Parsol 1789), amyl 506),...
Preservative sensitivity in the UK was last assessed 2000. Given changes preservative usage, we have re‐evaluated our patch test data order to detect any trend of sensitization. The results testing using extended British Contact Dermatitis Society Standard series were collected from 9 dermatology centres UK. Positive reactions each 10 allergens captured together with MOAHFLA indices for centre. In total, 6958 patients tested during period 2004–2005. current compared previously published...
The management of chronic hand eczema is often inadequate. There are currently no evidence‐based guidelines specifically for the eczema, and evidence established treatments not sufficient quality to guide clinical practice. This consensus statement, based on a review published data practice in both primary secondary care, intended eczema. It describes epidemiology pathogenesis its diagnosis effect patients' life. Management strategies include skin education programme, lifestyle changes, use...
Summary Background All centres use an empirically determined set of ‘standard’ test allergens for patch testing that contain the commoner environmental sensitizers. Objectives To assess validity British standard series 12 used in addition to 23 already European series. Patients and Methods Results 3062 consecutive patients tested seven across United Kingdom during year 2000 were analysed. The additional from positive rates were: methyl dibromoglutaronitrile 2·4%, carba mix 1·6%, tixocortol...