A5028805186- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Pesticide Exposure and Toxicity
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Cutaneous lymphoproliferative disorders research
- Research in Social Sciences
- Lymphoma Diagnosis and Treatment
- Dermatology and Skin Diseases
- T-cell and Retrovirus Studies
- Immunotoxicology and immune responses
- CAR-T cell therapy research
- Animal testing and alternatives
- Additive Manufacturing and 3D Printing Technologies
- Occupational Health and Safety Research
- Indoor Air Quality and Microbial Exposure
- Chemical Safety and Risk Management
- CNS Lymphoma Diagnosis and Treatment
- Immune Cell Function and Interaction
- Innovations in Concrete and Construction Materials
- Mechanical Behavior of Composites
- Agricultural safety and regulations
- Historical and Scientific Studies
- Antimicrobial agents and applications
Finnish Institute of Occupational Health
2015-2024
Helsinki University Hospital
2008-2010
Allergy and Asthma Federation
2007
ENT and Allergy
2006
Summary Background Occupational contact dermatitis is one of the most common occupational diseases in E urope. In order to develop effective preventive measures, detailed and up‐to‐date data on incidence, main causes professions at risk are needed. Objectives To describe pattern patch test reactivity allergens uropean baseline series patients with different occupations. Methods We analysed collected by S urveillance ystem C ontact A llergy ( ESSCA ) network from 2002 2010, 11 countries....
Background. The pattern of contact sensitization to the supposedly most important allergens assembled in baseline series differs between countries, presumably at least partly because exposure differences. Objectives. To describe prevalence tested consecutive patients years 2007 and 2008, discuss possible Methods. Data from 39 departments 11 European countries comprising Surveillance System on Contact Allergy network ( www.essca‐dc.org ) this period have been pooled analysed according common...
Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, products formulations regulatory intervention, the spectrum contact sensitization changes.To evaluate current allergens present European baseline series (EBS) across Europe.Retrospective analysis data collected by Surveillance System on Allergies (ESSCA, www.essca-dc.org) consecutively patch-tested patients, 2013/14,...
Continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing value included allergens.To present current EBS testing, obtained in 53 departments 13 countries during 2019 2020.Anonymised or pseudonymised individual data partly aggregated on demographic/clinical characteristics rest were prospectively collected centrally pooled analysed.In 2020, 22 581 patients tested EBS. Sensitization to nickel remained most common...
Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden affected individual society.To present sensitization frequencies most relevant allergens of European baseline series patients (OCD) compare profiles different occupations.The data 16 022 considered having OCD after patch testing within Surveillance System on Contact...
Summary Background Epoxy products are among the most common causes of occupational allergic contact dermatitis. Diglycidyl ether bisphenol A resin ( DGEBA‐R ) is important sensitizer in epoxy systems. Objectives To describe patients with dermatitis caused by products. Methods Patients reactions to chemicals were chosen from test files J anuary 1991 une 2014). Only allergy some component systems included. We analysed patch results, occupation, symptoms, and exposure data. Results found a...
Work-related skin diseases (WSD) are caused or worsened by a professional activity. Occupational (OSD) need to fulfil additional legal criteria which differ from country country. OSD range amongst the five most frequently notified occupational (musculoskeletal diseases, neurologic lung of sensory organs, diseases) in Europe.To retrieve information and compare current state national frameworks pathways manage patients with disease regard prevention, diagnosis, treatment rehabilitation...
Significance Contact dermatitis is an inflammatory skin disorder that arises from direct contact with irritants or allergens. Representing over 90% of occupational disorders, it has a considerable socioeconomic impact, and patients suffering can develop notable physical handicap. Current diagnostic regimes rely on allergy testing, exposure specification, follow-up visits. However, distinguishing the clinical phenotype irritant allergic dermatitis, which important for appropriate therapeutic...
In 2019, a number of allergens (haptens), henceforth, "the audit allergens," were considered as potential additions to the European Baseline Series (EBS), namely, sodium metabisulfite, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, imidazolidinyl Compositae mix II (2.5% or 5% pet), linalool hydroperoxides (lin-OOH), limonene (lim-OOH), benzisothiazolinone (BIT), octylisothiazolinone (OIT), decyl glucoside, and lauryl glucoside; Evernia furfuracea (tree moss), was additionally tested by...
Summary Background Exclusive breastfeeding for the first 6 months is recommended by World Health Organization and considered allergy preventive. However, it not known whether prolonging exclusive over provides further benefit in prevention. Objective The aim of this prospective 20‐year follow‐up study was to find out protective effect can be enhanced strictly 9 age. Methods A total 200 unselected healthy newborns were enrolled study. Their mothers encouraged maintain as long possible. number...
Abstract Background Although occupational contact urticaria (CU) and protein dermatitis (PCD) are considered frequent among workers with exposure to proteinaceous materials, data on occupations at risk the main causes of these skin diseases relatively limited. Objectives To report causative agents for CU PCD in Finnish Register Occupational Diseases (FROD). Methods We retrieved from FROD all recognized cases CU/PCD years 2005–2016. Results With 570 cases, constituted 11% study period....
Limonene is widely used as a fragrance substance and solvent in cleansing products. Oxidized limonene frequent contact allergen among consumers of cosmetics, personal care products, scented household cleaning Less known about the sources occupational exposure dermatitis caused by limonene.To report 14 patients with allergy to limonene.The were examined 2008-2013. An in-house preparation oxidized was patch tested 3% 5% petrolatum from 2008 August 2010, after this 3%, 1% 0.3% pet. From 2012...
Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI are common preservatives in industrial household products cosmetics. Occupational contact allergy to MCI/MI or has been reported among painters paint factory workers particular.To retrospectively describe patients with occupational at the Finnish Institute of Health (FIOH).Patch test files clinical records examined FIOH between January 2002 February 2013 were reviewed identify patients.Seventy-two 1745 showed positive...
Early markers of atopic predisposition are needed for targeting allergy preventive measures to high‐risk infants. An elevated cord serum immunoglobulin E (CS‐IgE) level is considered a risk factor subsequent in childhood. However, the previous studies have not assessed predictive value CS‐IgE follow‐up extended adulthood. We aimed at clarifying whether useful predicting manifestations up age 20 yr. A cohort 200 unselected, full‐term newborns were prospectively followed from birth The was...
Contact allergy to cocamidopropyl betaine has been attributed its impurities dimethylaminopropylamine and dimethylamine.To describe patients with positive patch test reactions betaine-related compounds in an occupational dermatology clinic.We reviewed the 2002-2009 records at Finnish Institute of Occupational Health for allergic betaine, dimethylaminopropylamine, dimethylamine, oleamidopropyl dimethylamine. Results. Irritant least one substances were seen 39% 1092 tested. Fifteen (1.3%)...
Summary Background Coconut fatty acids diethanolamide [cocamide diethanolamine (cocamide DEA )] is a surface‐active derivative of coconut oil that used in industrial, household and cosmetic products. Cocamide contact allergy has been reported relatively seldom. Objectives To describe cocamide ‐positive patients an occupational dermatology clinic. Methods We retrieved allergic reactions to from test files, studied the occupation, exposure, concomitant diagnoses positive patients. Results Of...
Summary Background Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. Objectives To study patterns of simultaneous patch test reactions to thiurams at the Finnish Institute Occupational Health in 1991–2015. Methods We searched files for patients with allergic thiuram mix, its four components, three dithiocarbamates, analysed these substances. Results found 155 who reacted positively least one or dithiocarbamate chemical series. Thirty‐four (22%) some...
Abstract Background Artificial nail materials are mixtures that prone to contain several sensitizing (meth)acrylates. It is not known whether the listing of (meth)acrylates correct in these products' packages. Protective gloves suited for work needed. Objectives To analyse gel and acrylic products chemically compare results with information product labels, study penetration artificial through selected disposable gloves. Methods We analysed 31 6 their (meth)acrylate content by gas...
Abstract Background Allergic contact dermatitis (ACD) from rubber glove usage is usually caused by additives such as the accelerators. However, in analyses of suspected gloves, ordinary allergens are not always found. Accelerator‐free gloves available, but some patients with accelerator allergy do tolerate them and might also be patch test positive to them. Objectives To identify chemically characterize a new allergen, 2‐cyanoethyl dimethyldithiocarbamate (CEDMC), gloves. We describe two...
Contact allergy to polyvinylchloride (PVC) gloves has been reported relatively seldom. In spring 2011, 5 of our patients had patch test reactions PVC gloves. We obtained a collection raw materials from industrial producers and suppliers chemical compounds be tested on with suspected glove contact allergy.To report the first results these new substances.The were newly substances, plastics glues series, isocyanates isocyanate prepolymers. analysed nine samples for triphenyl phosphate its...
Colophonium is a common contact allergen that present not only in household products but also occupational settings.To describe the sources of exposure to colophonium and occupations at risk allergy.We reviewed patch test files from years 2002 2017 Finnish Institute Occupational Health for patients with allergic reactions abietic acid. We analysed test, occupation data 39 diagnosed dermatitis (OACD) caused by colophonium.Of examined suspected dermatitis, 4.6% (n = 118) reacted positively...
Abstract Background Skin diseases are among the most common occupational diseases, but detailed analyses on their epidemiology, diagnoses, and causes relatively scarce. Objectives To analyze data skin disease in Finnish Register of Occupational Diseases (FROD) for (1) different diagnoses (2) main allergic contact dermatitis (ACD). Methods We retrieved recognized cases with (OSD) FROD from a 12‐year‐period 2005–2016 used national official labor force year 2012. Results analyzed total 5265...
Abstract Patch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of patch test (PT) allergens in Europe, however, currently scarce. This severely compromises adequate diagnostics contact allergy, leading to serious consequences affected patients. Against this background, European Society Contact Dermatitis (ESCD) has created a task force (TF) (i) explore current PT substances different member states, (ii) highlight some unique characteristics...