A5009455869- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Psoriasis: Treatment and Pathogenesis
- Contact Dermatitis and Allergies
- Particle physics theoretical and experimental studies
- Autoimmune Bullous Skin Diseases
- Quantum Chromodynamics and Particle Interactions
- Food Allergy and Anaphylaxis Research
- Drug-Induced Adverse Reactions
- Hidradenitis Suppurativa and Treatments
- High-Energy Particle Collisions Research
- IL-33, ST2, and ILC Pathways
- Dermatological and COVID-19 studies
- Nail Diseases and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Colorectal and Anal Carcinomas
- Occupational exposure and asthma
- Chemotherapy-related skin toxicity
- Hair Growth and Disorders
- Autoimmune and Inflammatory Disorders
- Skin Protection and Aging
- Mast cells and histamine
- Rheumatoid Arthritis Research and Therapies
University of Naples Federico II
2015-2025
University of Molise
2017-2024
University of Milan
2019-2020
University of Bari Aldo Moro
2017-2020
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2020
University of Turin
2020
Istituto Ortopedico Galeazzi
2019
Istituto Superiore di Sanità
2019
Sapienza University of Rome
2002-2018
University of Birmingham
2017
Several systemic therapies have been approved for the treatment of severe AD. In particular, Janus kinase inhibitors (JAKi), including abrocitinib, baricitinib, and upadacitinib, recently received approval patients with AD after being evaluated in several clinical trials. However, a few concerns raised regarding their long-term safety management these drugs real-world practice. this article we described results Delphi consensus aimed at describing knowledge on JAKi focusing, providing...
Hedgehog signaling is suggested to be a major oncogenic pathway in medulloblastoma, which arises from aberrant development of cerebellar granule progenitors. Allelic loss chromosome 17p has also been described as the most frequent genetic defect this human neoplasia. This observation raises question possible interplay between deletion and tumorigenic pathway. Here, we identify orthologue mouse REN(KCTD11), previously reported expressed differentiating low proliferating neuroblasts. Human...
Many studies have evaluated the role of individual nutrients on development psoriasis. However, only few investigated effect a healthy eating pattern, such as Mediterranean diet. In this study, we aimed to investigate relationship between adherence diet, body composition and severity psoriasis in group naïve-treatment patients with psoriasis.This is cross-sectional case-control observational study. Sixty-two (49 males 13 females, mean age: 50.2±10.5yrs) affected mild-to-severe were...
Treatment of moderate-to-severe atopic dermatitis (AD) in the elderly may be challenging, due to side-effects traditional anti-inflammatory drugs and comorbidities often found this age group. Furthermore, efficacy safety innovative such as dupilumab are not yet well known.A multicentre retrospective, observational, real-life study on was conducted a group patients aged ≥65 years affected by severe AD. Their main clinical features were also examined.Data with (EASI ≥24) AD treated at label...
Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden affected individual society.To present sensitization frequencies most relevant allergens of European baseline series patients (OCD) compare profiles different occupations.The data 16 022 considered having OCD after patch testing within Surveillance System on Contact...
Janus kinase (JAK) inhibitors, including upadacitinib, have been recently approved for the treatment of moderate-severe atopic dermatitis (AD) and real-world data on upadacitinib effectiveness safety are limited. This interim analysis aimed to assess throughout 48 weeks observation in a adult AD population. prospective study collected patients affected by moderate-to-severe treated with at dosage either 15 mg or 30 daily based physician decision. Upadacitinib was prescribed context national...
There is limited epidemiological evidence on outcomes associated with dupilumab exposure during pregnancy; monitoring pregnancy in large populations required.
Abstract Induction of long‐term depression (LTD) in rat striatal slices revealed that this form synaptic plasticity is coupled to an increased expression tissue‐plasminogen activator (t‐PA) mRNA, as detected by the mRNA differential display technique. To further investigate involvement gene remodelling following LTD, we recorded electrical activity from mice lacking encoding t‐PA (t‐PA‐KO) and wild‐type (WT) mice. Tetanic stimulation induced LTD large majority neurons WT Conversely, was...
Western dietary pattern is included among the environmental factors involved in pathogenesis of psoriasis. Nutritional data collection methods and gender differences might affect association between diet The 7-day food records considered "gold standard" self-administered frequency questionnaires. In this study, we evaluated intake, anthropometric measurements cardio-metabolic risk profile a group psoriatic patients compared with an age Body Mass Index (BMI)-matched control group. addition,...