Marcin Kurowski
A5048558482- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Exercise and Physiological Responses
- Urticaria and Related Conditions
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Drug-Induced Adverse Reactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Inflammatory mediators and NSAID effects
- Respiratory viral infections research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Immune Response and Inflammation
- Sports Performance and Training
- Dermatology and Skin Diseases
- Thermoregulation and physiological responses
- Immune Cell Function and Interaction
- Muscle metabolism and nutrition
- Pediatric health and respiratory diseases
- Eosinophilic Esophagitis
- Nutrition and Health Studies
- Water Treatment and Disinfection
- Neonatal Respiratory Health Research
Medical University of Lodz
2016-2025
Charité - Universitätsmedizin Berlin
2024
Humboldt-Universität zu Berlin
2024
Semmelweis University
2024
Goethe University Frankfurt
2024
University Hospital Frankfurt
2024
Ludwig-Maximilians-Universität München
2021
Approved on-demand treatments for hereditary angioedema attacks need to be administered parenterally, a route of administration that is associated with delays in treatment or withholding therapy.
Abstract In less than half a century, allergy, originally perceived as rare disease, has become major public health threat, today affecting the lives of more 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting budgets systems. More disturbingly, its prevalence impact are on rise, development that been associated with environmental lifestyle changes accompanying continuous process urbanization globalization. Therefore, there is an urgent need...
Abstract Background The prevalence of food allergy (FA) among European school children is poorly defined. Estimates have commonly been based on parent‐reported symptoms. We aimed to estimate the frequency FA and sensitization against allergens in primary eight countries. Methods A follow‐up assessment at age 6‐10 years a multicentre birth cohort was undertaken using an online parental questionnaire, clinical visits including structured interviews skin prick tests (SPT). Children with...
Coexistence of childhood asthma, eczema and allergic rhinitis is higher than can be expected by chance, suggesting a common mechanism. Data on multimorbidity from pan-European, population-based birth cohort study have been lacking. This compares the prevalence early-life risk factors these diseases in European primary school children.In prospective multicentre observational EuroPrevall-iFAAM study, we used standardized questionnaires sociodemographics, medical history, parental allergies...
Biomarkers that are able to predict the response omalizumab (OMA) in chronic spontaneous urticaria (CSU) highly valued. The aim of our study was evaluate UAS7 (urticaria activity score assessed for 7 days), DLQI (dermatology life quality index), SII (systemic immune-inflammation SIRI inflammation PLR (platelet/lymphocyte ratio) and NLR (neutrophil/lymphocyte a group 46 CSU patients treated 24 weeks with OMA (300 mg every 4 weeks). There were no statistically significant differences observed...
The aim of our study was to investigate effects 6-week pretreatment seasonal allergic rhinitis (AR) with cetirizine, and montelukast, alone in combination. Antihistamine/antileukotriene treatment is effective AR. Antihistamines may prevent AR symptoms while prophylactic activity antileukotrienes remains unclear.Sixty patients, aged 18-35 years, were randomized receive placebo, montelukast only, cetirizine or plus 6 weeks prior after the beginning grass pollen season. Mean self-recorded...
Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, osteoarthrosis (OA), healthy control (HC).PBMCs were stimulated LPS, biglycan mix. Cytokines analyzed supernatants ELISA. Expression toll-like mRNA leukocytes was using real-time qPCR.PBMCs RA spontaneously produced...
Concerns have been raised regarding the potential negative effects on human health of water disinfectants used in swimming pools. Among disinfection options, approaches using chlorine-based products typically preferred. Chlorine readily reacts with natural organic matter that are introduced mainly through bathers, leading to formation potentially harmful chlorination by-products (CBPs). The CBPs is particular concern since some epidemiologically associated development various clinical...
Abstract Background Respiratory epithelium integrity impairment caused by intensive exercise may lead to exercise-induced bronchoconstriction. Clara cell protein (CC16) has anti-inflammatory properties and its serum level reflects changes in airway inflammation. This study aimed investigate CC16 elite athletes seek associations of with asthma or allergy, respiratory tract infections (RTIs) immune response pathogens. Methods The was performed 203 Olympic athletes. Control groups comprised 53...
Abstract Introduction Exercise‐induced respiratory symptoms are often reported by professional athletes, but asthma and allergy underdiagnosed. Few studies used standardized questionnaires combined with clinical assessment to investigate among athletes. Objectives Assessment of the prevalence P olish athletes confronting it data. Methods Two hundred twenty‐two O lympic participated in project being part G lobal A llergy sthma E uropean N etwork ( GA 2 LEN ) study. Allergy status was...
Purpose: Periostin is considered a biomarker for eosinophilic airway inflammation and have been associated with NSAID-Exacerbated Respiratory Disease (NERD) chronic rhinosinusitis (CRS).In this study, we aimed to evaluate periostin in exhaled breath condensate (EBC) serum of patients various asthma phenotypes.Methods: The study included 40 asthmatic (22 NERD) 17 healthy controls.All the procedures (questionnaire, spirometry, FeNO, nasal swabs, EBC collecting, blood sampling) were performed...
Cannabis allergy is a relatively new phenomenon described in the 1970s. Its increased frequency has been observed over last years due to increasing therapeutic and recreational use of cannabis-based products. Sensitization possibly leading symptoms can occur not only through smoking cannabis, but also ingestion, inhalation pollen, or direct contact. The severity varies from benign pruritus anaphylaxis. There scant information available support clinicians throughout entire process, starting...
IIn nt tr ro od du uc ct ti io on n: : Polymorphisms within innate immunity genes are associated with allergic phenotypes but results variable.These associations were not analyzed respect to allergen exposure.We investigated of TLR and CD14 polymorphisms allergy in the context house dust mite (HDM) exposure.M Ma at te er ri ia al l a an nd d m me et th ho ds s: Children, aged 12-16 years (n = 326), recruited from downtown rural locations assessed by allergist.Skin prick tests, total...
Human parainfluenza virus type 3 (HPIV3), while infecting lower airway epithelial cells induces pneumonia and bronchiolitis in infants children, may lead to asthma exacerbations children adults. Respiratory viruses invading the epithelium activate innate immune response induce inflammatory cytokine release contributing pathophysiology of upper disorders. However, effects HPIV3 infection on nasal have not been well defined. The aim this study was evaluate effect cultured human (HNECs)...