A5012554636- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Drug-Induced Adverse Reactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mast cells and histamine
- Dermatologic Treatments and Research
- Food Allergy and Anaphylaxis Research
- Genetic and rare skin diseases.
- Nonmelanoma Skin Cancer Studies
- Skin Protection and Aging
- melanin and skin pigmentation
- Oral and gingival health research
- Allergic Rhinitis and Sensitization
- Cutaneous Melanoma Detection and Management
- Asthma and respiratory diseases
- Psoriasis: Treatment and Pathogenesis
- Skin and Cellular Biology Research
- Therapeutic Uses of Natural Elements
- Blood groups and transfusion
- Acne and Rosacea Treatments and Effects
- Respiratory and Cough-Related Research
- Dupuytren's Contracture and Treatments
- Platelet Disorders and Treatments
- Thermoregulation and physiological responses
Sechenov University
2016-2025
Science & Technology Park (Czechia)
2025
Regenerative Medicine Institute
2024
Lomonosov Moscow State University
2020-2023
The fate of melanin in the epidermis is great interest due to its involvement numerous physiological and pathological processes skin. Melanin localization can be assessed ex vivo using distinctive optical properties. exhibits a characteristic Raman spectrum band shape discernible near-infrared excited (NIR) fluorescence. However, detailed analysis capabilities depth-resolved confocal fluorescence microspectroscopy evaluation distribution human skin lacking. Here we demonstrate how fraction...
BackgroundPatient-reported outcome measures (PROMs) are validated and standardized tools that complement physician evaluations guide treatment decisions. They crucial for monitoring atopic dermatitis (AD) chronic urticaria (CU) in clinical practice, but there unmet needs knowledge gaps regarding their use practice.ObjecctiveWe investigated the global real-world of AD CU PROMs allergology dermatology clinics as well associated local regional networks.MethodsAcross 72 specialized allergy...
Edema, i.e., fluid accumulation in the interstitial space, accompanies numerous pathological states of human organism, including heart failure (HF), inflammatory response, and lymphedema. Nevertheless, techniques for quantitative assessment edema’s severity dynamics are absent clinical practice, analysis is mainly limited to physical examination. This fact stimulates development novel methods fast reliable diagnostics retention tissues. In this work, we focused on possibilities two...
Diagnosing skin diseases in children can be a complex interdisciplinary problem. Incontinentia pigmenti (IP), also known as Bloch-Sulzberger syndrome, is rare hereditary genodermatosis related to mutation the IKBKG gene. We present family case of IP described from perspective various specialists, including dermatologists, oncologists, geneticists, dentists, and trichologists. The peculiarity this development squamous cell carcinoma (SCC) on shin 10-year-old female patient with IP. had...
Диагностика аутоиммунных буллезных дерматозов, в том числе буллезного пемфигоида Левера, характеризующегося большим разнообразием клинических проявлений, а во многих случаях – тяжелым течением и высокой смертностью, остается одной из наиболее сложных проблем дерматологии. Высокая частота диагностических ошибок обусловлена не только вариабельностью форм но недостаточной точностью существующих методов диагностики, также сложностью их выполнения. Несомненным преимуществом обладают неинвазивные...
Most cases of malignant epithelial skin neoplasms including actinic keratosis and basal cell carcinoma, which are characterized by the most complicated course numerous clinical morphological options, involve dermatoheliosis progression. The risk transformation into carcinoma varies from 0.1% to 20% up 80% in multiple AK lesion foci. A non-invasive method known as reflectance confocal laser scanning microscopy is promising one for purposes early diagnostics signs pointing at neoplasm...
The efficacy of the long-acting drug hyaluronidase (bovhyaluronidase azoximer, BHA) in acne and postacne patients has been studied. main criteria for post-acne therapy assessment by confocal laser scanning microscopy Doppler flowmetry are proposed.Materials methods. Randomized, double-blind, placebo-controlled study, comparative parallel groups. 90 aged 18 to 35 years (23.76 ± 4.59 years) with medium severe were divided into 2 groups 45 each randomization (the first group received BHA...
Most cases of malignant epithelial skin neoplasms including actinic keratosis and basal cell carcinoma, which are characterized by the most complicated course numerous clinical morphological options, involve dermatoheliosis progression. The risk transformation into carcinoma varies from 0.1% to 20% up 80% in multiple AK lesion foci. A non-invasive method known as reflectance confocal laser scanning microscopy is promising one for purposes early diagnostics signs pointing at neoplasm...
The efficacy of using autologous platelet-enriched plasma (auto-OTP) in women different age groups with involutionally altered facial skin by the method confocal laser scanning microscopy was evaluated. Own results treatment 50 patients aged from 35 to 55 years clinical manifestations are presented. As a result therapy, decrease signs aging observed all women, but effect more pronounced group 45 (97%, which 76% significant improvement, 21% improvement). In second (46-55 years), after course...
Background. Omalizumab, a recombinant humanized anti-IgE antibody, is an effective treatment option for patients with antihistamine-resistant chronic spontaneous urticaria (CSU). 14–36 % of CSU have concomitant inducible (CIndU). However, it unclear whether comorbid CIndU can benefit from this treatment. Aim the study. To assess efficacy and safety omalizumab in two several types CIndU. Materials methods. were diagnosed as recommended by international guideline. Both female treated 300 mg...
Хроническая спонтанная крапивница (ХСК) распространенное заболевание кожи, при котором волдыри и/или ангиоотеки появляются без видимой причины и сохраняются не менее 6 недель. Рекомендуемое лечение ХСК заключается в назначении Н1-антигистаминных препаратов второго поколения (терапия первой-второй линии), омализумаба циклоспорина. Выявление, изучение внедрение маркеров, предсказывающих вероятность ответа пациента на терапию, позволит оптимизировать фармакотерапию заболевания путем повышения...