A5070556047- Psoriasis: Treatment and Pathogenesis
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Wnt/β-catenin signaling in development and cancer
- Skin and Cellular Biology Research
- Dermatology and Skin Diseases
- Dermatological and Skeletal Disorders
- Pregnancy and preeclampsia studies
- Mast cells and histamine
- Eosinophilic Disorders and Syndromes
- Autoimmune and Inflammatory Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Estrogen and related hormone effects
- Dermatologic Treatments and Research
- Tumors and Oncological Cases
- Asthma and respiratory diseases
- RNA regulation and disease
- Cutaneous lymphoproliferative disorders research
- Hair Growth and Disorders
- CNS Lymphoma Diagnosis and Treatment
- Vasculitis and related conditions
- Dupuytren's Contracture and Treatments
- IL-33, ST2, and ILC Pathways
- Connective tissue disorders research
- Leech Biology and Applications
Medical University of Lublin
2013-2024
Psoriasis is a chronic debilitating skin disease with an estimated prevalence reaching 2% of the worldwide population. Psoriatic driven by network complicated reciprocal interactions among innate and adaptive mechanisms immune system structural components skin. Interleukin (IL)-22 mediates keratinocyte proliferation epidermal hyperplasia, inhibits terminal differentiation keratinocytes, induces production antimicrobial proteins. The aim this study was assessment IL-22 levels its correlation...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Pietrzak A, Chabros P, Grywalska E, et al. Serum concentration of interleukin 6 is related to inflammation and dyslipidemia in patients with psoriasis. Advances Dermatology Allergology/Postępy Dermatologii i Alergologii. 2020;37(1):41-45. doi:10.5114/ada.2018.78028. APA Pietrzak, A., Chabros, P., Grywalska, E., D., Kandzierski, G., & Wawrzycki, B. (2020). Alergologii, 37(1), 41-45....
BackgroundPatient-reported outcome measures (PROMs) are validated and standardized tools that complement physician evaluations guide treatment decisions. They crucial for monitoring atopic dermatitis (AD) chronic urticaria (CU) in clinical practice, but there unmet needs knowledge gaps regarding their use practice.ObjecctiveWe investigated the global real-world of AD CU PROMs allergology dermatology clinics as well associated local regional networks.MethodsAcross 72 specialized allergy...
Cutaneous larva migrans (CML) is a frequent parasitic infestation caused by migration of animal hookworm larvae into the human epidermis. This skin disease common in warmer climates among people, who have contact with contaminated soil. Clinical manifestation CML an itchy, erythematous, linear tract, which appears days to even months after exposure infested sand or Diagnosis established on clinical presentation. We describe case acquired during holiday Brazil.
Ichthyosis Follicularis, Atrichia and Photophobia (IFAP) syndrome is a rare genodermatosis due to mutations of the MBTPS2 gene. To date fewer than 40 cases have been described in literature. present first case IFAP diagnosed Poland novel mutation MBTPS2, review relevant literature on this genodermatosis. A 16-year-old male presented with typical clinical features IFAP, along psoriasiform skin plaques, nail dystrophy, facial dysmorphy, mental retardation, severe skeletal abnormalities...
Cutaneous T cell lymphomas other than mycosis fungoides, Sezary syndrome, and primary cutaneous CD30+ lymphoproliferations constitute less 10% of all lymphomas. Primary small/medium CD4+ lymphoma is a member this third group lymphomas, separated out as provisional entity in the World Health Organization classification - European for Research Treatment Cancer (WHO-EORTC) classification. It still awaits development more precise diagnostic criteria optimal therapy. We report case CD4 +...
Diffuse cutaneous mastocytosis is the rarest subtype of among those that affect children. A 7-month-old girl presented at birth dry and thickened skin. On second day life, tense blisters appeared on erythrodermic areas during next days spread over face, trunk, limbs. The skin was bright red, had a "peau d'orange" appearance, considerably with numerous translucent hemorrhagic blisters. biopsy revealed massive infiltration dermis mast cells, leading to diagnosis diffuse mastocytosis. Systemic...
Abstract The article focuses on the eruption of palmoplantar pustular psoriasis, which was documented in a 53-year-old man diagnosed with prostate cancer bone metastases. This clinical finding made during routine hormone therapy and palliative radiotherapy. local improvement skin lesions achieved following administration topical ointments use UVA 311 nm radiation therapy. management this subject resulted malaise, onset diabetes mellitus increased concentration serum lipids. Interestingly,...
Abstract Background Clouston syndrome belongs to the family of ectodermal dysplasias. So far, a defective immune response has not been reported in syndrome. We report, for first time, immunological particularities large multigenerational Polish with Methods Five members same syndrome, aged 6–76 years, and 20 healthy volunteers, 19–73 were enrolled study. In all participants, ability neutrophils phagocytize opsonized Escherichia coli was assessed. Granulocyte oxidative burst determined...
Abstract Background Skin lesions on the feet and foot deformities impair daily activities decrease quality of life. Although substantial occur in many genodermatoses, few reports have been published this topic. Therefore, we performed a retrospective chart review to identify patients with genodermatoses disorders. We included 16 patients, who were investigated clinically molecular biology. Results The following detected: autosomal recessive congenital ichthyosis (ARCI, n = 7); palmoplantar...
Psoriasis is currently considered a multifactorial disease, which can coexist with many somatic and psychological disorders. We present the case of 50-year-old woman referred to our department due erythroderma concomitant peculiar violaceous, polycyclic lesions most likely induced by medications. Past medical history revealed numerous systemic disorders, including metabolic syndrome, hypertension, cardiac insufficiency, obesity, depression. Additional examinations consultations demonstrated...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Wawrzycki B, Pietrzak A, Chodorowska G, et al. Ectrodactyly-ectodermal dysplasia-clefting syndrome with unusual cutaneous vitiligoid and psoriasiform lesions due to a novel single point TP63 gene mutation. Advances in Dermatology Allergology/Postępy Dermatologii i Alergologii. 2019;36(3):358-364. doi:10.5114/ada.2018.73437. APA Wawrzycki, B., Pietrzak, A., Chodorowska, G., Filip, Petit, V., & Rudnicka, L....
<title>Abstract</title> <bold>Background</bold>: The Mendelian Disorders of Cornification (MeDOC) comprise a large number disorders that are manifested by either localised (palmoplantar keratoderma, PPK) or generalised (ichthyoses) symptoms. MeDOC highly heterogenic in terms genetics and phenotype. Consequently, diagnostic process is challenging before implementation the next generation sequencing, was mostly symptomatic, not causal, which limited research on those diseases. aim study to...
Abstract Background The Mendelian Disorders of Cornification (MeDOC) comprise a large number disorders that present with either localised (palmoplantar keratoderma, PPK) or generalised (ichthyoses) signs. MeDOC are highly heterogenic in terms genetics and phenotype. Consequently, diagnostic process is challenging before implementation the next generation sequencing, was mostly symptomatic, not causal, which limited research on those diseases. aim study to genetically characterise cohort 265...
Background: Dermatological conditions extend beyond physical symptoms, profoundly impacting the psychological well-being of patients. This study explores intricate relationship between depressive quality life (QoL), and personality traits in individuals diagnosed with specific genodermatoses. Methods: The cohort comprised 30 patients genodermatoses treated at dermatology clinic, a healthy control group. Standardized survey questionnaires: Dermatology Life Quality Index (DLQI), Beck’s...
Bullous pemphigoid is the most common autoimmune blistering disorder in elderly. It affects people aged 70 years or older. Clinically it characterized by intensely pruritic eruption consisting of widespread tense blisters on an erythematous background. associated with cellular and humoral responses against hemidesmosomal components skin mucous membranes. In contrast, infantile bullous exceedingly rare disease presents some unique features like favorable prognosis, possible association...
1. Stone JH. The classification and epidemiology of systemic vasculitis. In: Firestein GS, Budd RC, Harris ED, McInnes IB Jr, Shaun R, Sergent JS (ed) Kelley’s Textbook Rheumatology, 8th edn. Saunders, Philadelphia; 2009: pp 1401–1408. CrossRef Google Scholar