Witold Krupski

ORCID: 0000-0002-3304-4961
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About
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Research Areas
  • Bone health and osteoporosis research
  • Animal Nutrition and Physiology
  • Medical Imaging and Analysis
  • Spine and Intervertebral Disc Pathology
  • Bone health and treatments
  • Bone Metabolism and Diseases
  • Comparative Animal Anatomy Studies
  • Spinal Fractures and Fixation Techniques
  • Growth Hormone and Insulin-like Growth Factors
  • Genetic and phenotypic traits in livestock
  • Diet and metabolism studies
  • Metabolism and Genetic Disorders
  • Pelvic and Acetabular Injuries
  • Dental Radiography and Imaging
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Bone and Dental Protein Studies
  • Gastrointestinal disorders and treatments
  • Meat and Animal Product Quality
  • Livestock and Poultry Management
  • Radiomics and Machine Learning in Medical Imaging
  • Bone Tumor Diagnosis and Treatments
  • Gastric Cancer Management and Outcomes
  • dental development and anomalies
  • Medical Imaging and Pathology Studies
  • Mast cells and histamine

Medical University of Lublin
2014-2025

Membrane Reactor Technologies (Canada)
2016

Lublin Oncology Center
2014

University of Life Sciences in Lublin
2012

Minneapolis VA Medical Center
2008

Instytut Medycyny Wsi im. Witolda Chodźki
1996-2007

Nutritional manipulations during fetal growth may induce long-term metabolic effects in postnatal life. The aim of the study was to test whether combined treatment pregnant sows with alpha-ketoglutarate and β-hydroxy-β-methylbutyrate induces additive on skeletal system properties offspring. performed 290 pigs obtained from 24 divided into 4 equal groups subjected experimental two weeks before delivery. first group consisted control sows, while second received alpha-ketoglutarate. third...

10.1186/1743-7075-9-39 article EN cc-by Nutrition & Metabolism 2012-01-01

Alzheimer's disease (AD) is known to exhibit well characterized pathologies including the extracellular accumulation of amyloid plaques, intra-axonal presence neurofibrillary tangles, and glial hypertrophy. Nevertheless, nature myelin pathology in AD has not been studied. Recent studies on animal models AD, however, revealed focal demyelination within amyloid-β plaques hippocampus.In a view this finding, we decided assess humoral response against proteins sheath hope identifying early...

10.3233/jad-150309 article EN Journal of Alzheimer s Disease 2015-08-28

Effects of increased stocking density and heat stress on growth, feed conversion, carcase characteristics skeletal system properties in turkeys were determined. One-day-old males (n=1674) divided into two weight-matched groups exposed to different environmental conditions. Controls reared at a 2.8 birds/m(2) thermo-neutral temperature (TnT group), while the experimental group was heat-stress (HSID group) 3.4 ambient by 5°C. At 28 days age, 27 birds from each sacrificed, 126 54 slaughtered....

10.1136/vr.102216 article EN Veterinary Record 2014-11-05

The objective of the study was to evaluate effect denervation and alpha-ketoglutarate (AKG) administration on development osteopenia in turkey radius. At 22 d age, all turkeys were subjected neurectomy right Control given a saline solution into crop each day for 97 d. Experimental 0.4 g AKG/kg BW day. After 98 d, not affected by AKG treatment. Volumetric bone mineral density radius measured quantitative computed tomography. Mechanical properties tested using 3-point bending test....

10.1093/ps/84.10.1604 article EN cc-by-nc-nd Poultry Science 2005-10-01

The aim of the study was to present classification anatomical variations stomach, based on radiological and historical data. In years 2006-2010, 2,034 examinations upper digestive tract were performed. Normal stomach anatomy or different organ shape and/or topography without any organic radiologically detectable gastric lesions revealed in 568 821 cases, respectively. Five primary groups established: abnormal position along longitudinal (I) horizontal axis (II), as well (III) connections...

10.1007/s00276-011-0893-8 article EN cc-by-nc Surgical and Radiologic Anatomy 2011-11-05

Among bones building the axial and appendicular skeleton, mandible is characterized by unique morphological functional traits. The aim of study was to evaluate morphological, densitometric mechanical properties in 5-month-old Polish Merino sheep. Using quantitative computed tomography, volumetric bone mineral density (vBMD) calcium hydroxyapatite cortical (CbCa-HA), mean vBMD (MvBMD) total volume were determined. tomography cross-sectional scans mandible, area, second moment inertia,...

10.1186/s12917-016-0921-3 article EN cc-by BMC Veterinary Research 2016-12-01

1. The aim of the study was to investigate effects feeding fast growing turkeys with differentiated dietary calcium (Ca) content, and partial replacement vitamin D(3) in feed 25-hydroxycholecalciferol (25(OH)D(3)), on skeletal properties. 2. One-day-old Big-6 male (n = 1008) were randomly divided into 4 groups, two subgroups created within each group. groups levels Ca provision feed, namely 85% National Research Council (NRC) recommendation (Group Ca(1)); 95% as above Ca(2)); 105% Ca(3));...

10.1080/00071668.2011.631984 article EN British Poultry Science 2011-12-01

We studied the changes in morphological, geometric, densitometric, and mechanical parameters of femur tibia during 56 D rearing chickens with different growth rates. Ten were collected from fast-growing (FG) 2 types medium-growing (MGH MGGP) immediately after hatching (0 D) on 7, 14, 21, 35, 42, 49, life. The bone across all genetic groups found to be similar 0 D, exceptions lower percentage contribution weight (BW) FG (P < 0.05), total volume MGGP maximum elastic strength MGH 0.05). bones...

10.3382/ps/pez445 article EN cc-by-nc-nd Poultry Science 2019-08-10

In April 2017 midostaurin was approved by the US Food and Drug Administration for treatment of patients with aggressive systemic mastocytosis (ASM). So far, very limited real world data on its efficacy is available. Thirteen aged from 48 to 79 years, who received in early access program, were included study. Midostaurin used both first (n = 5) subsequent lines 8). The median duration exposure 9 months. Most (77%, n 10) had a clinical improvement already as soon second month therapy....

10.3390/jcm10051109 article EN Journal of Clinical Medicine 2021-03-07

Summary The long‐term effect of α ‐ketoglutarate (AKG) given for 21–24 days post‐partum , on the skeleton commercial pigs, was investigated. In experiment A, 12 pigs were AKG [0.1 g/kg body weight (b.w.) per day os ] while controls administered vehicle. At 169, left and right femur, humerus sixth ribs analysed mechanical geometrical properties quantitative computed tomography. B, 32 piglets divided equally into an group (0.3 b.w. day) or a control group. Blood, taken at 24 53 plasma 17 β...

10.1111/j.1439-0396.2007.00742.x article EN Journal of Animal Physiology and Animal Nutrition 2007-11-08

Abstract The aim of the study was to evaluate interrelationships between final body weight, and morphometric, densitometric, mechanical properties mandible in 6-month-old Polish Large White pigs exposed dexamethasone nanocalcium. performed on 27 males, castrated 28th d after weaning, reared until age 6 months, which animals were slaughtered, obtained. divided into four experimental groups: given per os nanopartical calcium, injected with dexamethasone, both calcium injections, placebo. After...

10.2478/v10213-012-0032-2 article EN cc-by-nc-nd Bulletin of the Veterinary Institute in Pulawy 2012-06-01

The aim of this study was to evaluate the influence long-term denervation on volumetric bone mineral density, and geometrical mechanical properties humerus in turkeys. experiment conducted from d 22 after hatching until wk 17 life. All experimental birds (male turkeys) were randomly divided into 2 weight-matched groups. first group turkeys served as control underwent a sham operation right wing, second subjected surgical humerus. performed by neurectomy radialis mediano-ulnaris nerves region...

10.1093/ps/84.5.718 article EN cc-by-nc-nd Poultry Science 2005-05-01
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