A5081481780- Acute Lymphoblastic Leukemia research
- Systemic Lupus Erythematosus Research
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Respiratory viral infections research
- Multiple Sclerosis Research Studies
- COVID-19 Impact on Reproduction
- Autoimmune Neurological Disorders and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Kidney Stones and Urolithiasis Treatments
- Skin Diseases and Diabetes
- Therapeutic Uses of Natural Elements
- Amino Acid Enzymes and Metabolism
- Multiple and Secondary Primary Cancers
- Vascular Anomalies and Treatments
- Urological Disorders and Treatments
- Complementary and Alternative Medicine Studies
- Porphyrin Metabolism and Disorders
- Systemic Sclerosis and Related Diseases
- Influenza Virus Research Studies
- Ureteral procedures and complications
- Otitis Media and Relapsing Polychondritis
- Cancer Mechanisms and Therapy
Medical University of Lublin
2021-2025
Multiple myeloma (MM) is the second most common hematologic malignancy in world and accounts for 15% of primary hemocytopathies, with an ever-increasing number new cases. It asymptomatic 30% instances; hence, determination highly sensitive specific markers necessary to make a proper diagnosis. In last 20 years, miRNAs, involved regulating expression genes responsible cell proliferation differentiation, including tumor cells, have been identified as potential diagnostic prognostic markers....
AMA Dubaj M, Dembowska A, Bigosiński K, Belniak E, Rejdak K. Coexistence of multiple sclerosis and systemic lupus erythematosus – a case report. Advances in Psychiatry Neurology/Postępy Psychiatrii i Neurologii. 2024. doi:10.5114/ppn.2023.134444. APA Dubaj, M., Dembowska, A., Bigosiński, K., Belniak, E., & Rejdak, (2024). https://doi.org/10.5114/ppn.2023.134444 Chicago Maciej, Aleksandra Karol Ewa Konrad Rejdak. "Coexistence report". Harvard MLA Maciej et al. report." Neurologii, Vancouver
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by high heterogeneity of clinical manifestations and uncertain prognosis. Although the mortality rate due to SLE has decreased significantly in recent decades, there still a need find good tools measure activity for early detection exacerbations treatment planning. Over more than dozen scales/indicators have been developed, with Disease Activity Index (SLEDAI) being most popular. More recently, new Score (SLE-DAS)...
AMA Dembowska A, Dubaj M, Bigosiński K, Raniewicz Mitura-Lesiuk M. Synchronous neoplasms in a paediatric patient. Pediatria Polska - Polish Journal of Paediatrics. 2024. doi:10.5114/polp.2024.135857. APA Dembowska, A., Dubaj, M., Bigosiński, K., Raniewicz, & Mitura-Lesiuk, (2024). https://doi.org/10.5114/polp.2024.135857 Chicago Aleksandra, Maciej Karol Mateusz and Małgorzata Mitura-Lesiuk. "Synchronous patient". Harvard MLA Aleksandra et al. patient." Paediatrics, Vancouver
: Hyperleukocytosis, defined as a total leukocyte count of more than 50,000/mm
VEXAS syndrome was first described in 2020. It is a of autoimmune and haematological manifestations caused by somatic mutation the UBA1 gene bone marrow progenitor cells. This results abnormal protein ubiquitination systemic inflammatory process. The main symptoms include recurrent fever, polychondritis, neutrophilic dermatosis, vasculitis, ophthalmic with myelodysplastic syndrome. treatment has proven to be effective high-dose corticosteroids, monoclonal antibodies directed against...
An adrenal incidentaloma (AI) is any lesion ≥ 1 cm in diameter detected during radiological diagnostics unrelated to suspected pathology. Each case of an AI requires extended hormonal and imaging assessments accurately determine the nature tumor its activity. The frequency this tumor’s has increased exponentially due continuous progress development methods, especially computed tomography magnetic resonance imaging. most common etiology AIs are hormonally inactive adenomas cortex, but there...
Medullary sponge kidney (renal spongiosis), (MSK) is a rare developmental anomaly of the unknown cause. It presumed, that people with genetic predisposition (<5% family occurrence) are prone to disease. The peak diagnosis between ages 20-50, usually by chance (due lack symptoms) during an abdominal X-ray, where so-called nephrocalcinosis (calcifications in kidney) can be observed. Another radiologic test, may suggest condition question ultrasound, cysts up 8 mm diameter medullary part and...
The gut microbiota plays an important role in the proper functioning of human body. microbes present intestines are for correct digestive tract as well other, often distant, organs Unfavorable conditions may lead to imbalance intestinal microorganisms, leading unfavorable consequences.
 Under physiological conditions, large intestine is inhabited by a significant amount bacteria, while small contains only them. appearance pathological gastrointestinal colonization excessive which,...
1. Lenhardt R. Body temperature regulation and anaesthesia. Handb Clin Neurol. 2018;157:635–644. doi: 10.1016/B978–0–444–64074–1.00037–9. CrossRef Google Scholar
Acute lymphoblastic leukaemia (ALL) is the most common malignancy among children. It originates from over-proliferating immature lymphoid cells called lymphoblasts. Modern genetic studies have shown that aetiology of ALL correlated with numerous chromosomal aberrations, including activating mutation JAK/STAT pathway. This pathway responsible for regulating transmission signals extracellular cytokines to nucleus cells, their growth, differentiation and immune response. With proper patient...
1. Bhojwani D, Yang JJ, Pui CH. Biology of childhood acute lymphoblastic leukemia. Pediatr Clin North Am. 2015;62(1):47–60. doi:10.1016/j. pcl.2014.09.004. Google Scholar
1. Kovacova-Hanuskova E, Buday T, Gavliakova S, Plevkova J. Histamine, histamine intoxicationand intolerance. Allergol Immunopathol (Madr). 2015;43:498–506. https://doi.org/10.1016/J.ALLE.... CrossRef Google Scholar
Influenza (the flu) is an acute infectious disease caused by viruses of the Orthomyxoviridae family, causing a wide variety symptoms in humans, ranging from mildly disturbing daily activities to life-threatening pneumonia, depending on state their immune system. The annual increase incidence this called "the flu season", which periodic epidemic that affects people all around world. Despite individual, economic and epidemiological risks associated with infection influenza virus, often...