A5017442709- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Drug-Induced Adverse Reactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Medicine and Dermatology Studies History
- Pharmaceutical studies and practices
- Histiocytic Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Nail Diseases and Treatments
- Biomedical and Chemical Research
- Eosinophilic Disorders and Syndromes
- Psoriasis: Treatment and Pathogenesis
- Immunotherapy and Immune Responses
- Acne and Rosacea Treatments and Effects
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pesticide Exposure and Toxicity
- Antimicrobial agents and applications
- Leprosy Research and Treatment
- Biotin and Related Studies
- Occupational exposure and asthma
Cliniques Universitaires Saint-Luc
2015-2024
UCLouvain
2015-2024
Société Française de Cardiologie
2024
Background. Biomarkers of disease activity/severity and criteria autoimmune chronic spontaneous urticaria (CSU) are still a matter debate. Objective. To investigate possible correlations between clinical biological markers their associations with: 1) activity, 2) resistance to H1-antihistamines, 3) autoimmunity 4) autologous serum skin test (ASST) in patients with CSU. also analyze parameter modifications CSU treated omalizumab. Materials methods. Disease H1-antihistamines response presence...
Abstract Background The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this been identified as one the culprit allergens. Objectives To report on presence IBOA devices produced by Medtronic, namely, Enlite insulin infusion set Paradigm MiniMed Quick‐set. Patients Methods Five patients reacting to and/or Quick‐set observed three clinics (two Belgian Swedish) were patch tested with baseline other series, well IBOA; four...
Abstract Background Most diabetic patients sensitized to FreeStyle Libre react isobornyl acrylate (IBOA), with a considerable number of them also showing unexpected positive patch test reactions sesquiterpene lactone (SL) mix (SLM) tested in the baseline series. Objectives To compile results subjects affected, and provide potential explanations for this association. Patients Methods Fifty‐three Freestyle Libre‐allergic were IBOA and/or SLM, several components SLM. Chromatographic analyses...
We report a case series of 8 patients who developed chronic spontaneous urticaria (CSU) following vaccination against SARS-CoV-2 infection (Table I).Table IPatient clinical dataPatient no.SexAge (y)VaccineUrticaria onset afterDelay (d)Flare-up after second doseFlare-up third doseWheals/angioedemaHistory CUTreatment CSUConcomitant AI diseaseDuration CSU (mo)Duration follow-up since (mo)CSU resolution∗CSU resolution means no more wheals and/or angioedema, and were able to discontinue their...
This case series examines the effectiveness of Janus kinase inhibitor upadacitinib for treatment granulomatous cheilitis.
Allergic contact dermatitis caused by glucose sensors has been recently described in diabetics, mostly adult patients. Isobornyl acrylate and N-N dimethylacrylamide are the potent causative agents.To describe a child population with sensors, determine allergen, assess prevalence of isobornyl (IBOA) sensitization.Overall, 12 children reaction to medical devices, either or insulin sets, were patch tested European baseline series, glues rubber, (meth) acrylates piece adhesive part sensor...
Adverse cutaneous reactions to diabetes medical devices (glucose sensors and insulin pumps) are described, notably allergic contact dermatitis (ACD) with isobornyl acrylate (IBOA) N,N dimethylacrylamide (DMAA) as the main allergen.To determine if all cases of adverse observed (ie FreeStyle Libre, Enlite or pumps), referred our department suspected allergies confirmed ACD.Fifty-two patients who presented skin were patch tested European baseline series, a plastic glues (meth) acrylates piece...
Limited information is available on the use of omalizumab (OMA) updosing since its introduction as a second-line therapy in chronic spontaneous urticaria (CSU) 2014. Practical guidelines from health authorities are lacking, and specific characteristics patients requiring higher doses remain unknown. Our objectives were to characterize patterns OMA (defined changes dose and/or injection intervals), identify predictive factors associated with updosing, improve CSU management. We conducted...
Abstract Background Chronic spontaneous urticaria (CSU) is characterized by the repeated occurrence of persistent hives and/or angioedema for ≥6 weeks, without specific external stimuli. H 1 ‐antihistamines have long been standard care CSU, but many patients remain uncontrolled even at 4× approved dose. Add‐on therapy with omalizumab has proven effective in clinical trials, little known about treatment Belgium. Objective To collect real‐world data on adults CSU Methods This was an...
Allergic contact dermatitis has been described as a type IV reaction caused by antigen-specific T cells. Central roles for CD8+ cytotoxic cells effector and CD4+ regulatory have suggested. helper (Th) 2 Th1 cytokines implicated; however, the nature of allergen influences Th response.To determine types expressed in patients allergic to p-phenylenediamine (PPD).Serial skin biopsies areas with positive patch test reactions 29 PPD-sensitized were collected. cell markers cytokine expression...