A5090012430- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Drug-Induced Adverse Reactions
- Contact Dermatitis and Allergies
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Autoimmune and Inflammatory Disorders
- Dermatology and Skin Diseases
- Psychosomatic Disorders and Their Treatments
- Mast cells and histamine
- Eosinophilic Esophagitis
- Skin and Cellular Biology Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Eosinophilic Disorders and Syndromes
- Skin Diseases and Diabetes
- Pharmaceutical studies and practices
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Body Image and Dysmorphia Studies
- Chemotherapy-related skin toxicity
- Mental Health and Psychiatry
- Inflammatory Myopathies and Dermatomyositis
- Lymphoma Diagnosis and Treatment
- melanin and skin pigmentation
- Dermatological and COVID-19 studies
Universitair Ziekenhuis Brussel
2015-2024
Vrije Universiteit Brussel
2015-2024
Technical University of Munich
2009-2019
Klinikum rechts der Isar
2013-2015
University Medical Center of the Johannes Gutenberg University Mainz
2015
Johannes Gutenberg University Mainz
2015
Charité - Universitätsmedizin Berlin
2015
CK-CARE
2010-2014
Helmholtz Zentrum München
2009-2013
Ludwig-Maximilians-Universität München
2013
This update and revision of the international guideline for urticaria was developed following methods recommended by Cochrane Grading Recommendations Assessment, Development Evaluation (GRADE) working group. It is a joint initiative Dermatology Section European Academy Allergology Clinical Immunology (EAACI), Global Allergy Asthma Network (GA²LEN) its Urticaria Angioedema Centers Reference Excellence (UCAREs ACAREs), Forum (EDF; EuroGuiDerm), Asia Pacific Association Allergy, with...
Abstract Skin tests are of paramount importance for the evaluation drug hypersensitivity reactions. Drug skin often not carried out because lack concise information on specific test concentrations. The diagnosis allergy is based history alone, which an unreliable indicator true hypersensitivity.To promote and standardize reproducible testing with safe nonirritant concentrations in clinical practice, E uropean N etwork A cademy llergy C linical I mmunology ( EAACI ) Interest Group Allergy has...
Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients....
The simultaneous occurrence of psoriasis driven by type 1 helper T (Th1) cells and 17 (Th17) atopic eczema dominated 2 (Th2) is rare. Here, we describe three patients with co-occurring an antagonistic course distinct T-cell infiltrates in lesions from those eczema. Sensitized had a reaction to epicutaneous allergen challenge, clinically histologically verified containing large number allergen-reactive cells. These findings support causative role for triggered specific antigens both...
Structured educational programmes for patients at risk anaphylaxis have not yet been established. Patients and caregivers often lack adequate skills in managing the disease.To investigate effects of structured patient education intervention on knowledge, emergency management psychological parameters with previous episodes affected children 95 (11 male, 84 female, mean age 37 years) 98 (32 66 47.5 were randomly assigned to an (IG) or control group (CG) a multicentre randomized controlled...
The strongest and best-documented risk factor for drug hypersensitivity (DH) is the history of a previous reaction. Accidental exposures to drugs may lead severe or even fatal reactions in sensitized patients. Preventable prescription errors are common. They often due inadequate medical poor assessment recurrence Proper documentation essential information doctor make sound therapeutic decision. European Network on Drug Allergy Interest Group Academy Clinical Immunology have formed task force...
Psoriasis is characterized by an apoptosis-resistant and metabolic active epidermis, while a hallmark for allergic contact dermatitis (ACD) T cell-induced keratinocyte apoptosis. Here, we induced ACD reactions in psoriasis patients sensitized to nickel (n = 14) investigate underlying mechanisms of simultaneously. All developed clinically histologically typical upon challenge even close proximity pre-existing plaques. However, the reaction was delayed as compared non-psoriatic patients, with...
Objective: To explore a combination of health-related psychobehavioral features as potential positive criteria for somatoform disorders (SFD). Currently, SFD can only be diagnosed in the absence sufficient organic symptom explanation, resulting low criterion validity and delay appropriate therapy. Methods: Cross sectionally, we studied various characteristics 197 inpatients with suspected allergies. At beginning medical work-up, patients were interviewed completed set self-rating...
Vibratory angio‐oedema is a rare form of physical urticaria characterized by pruriginous weals and at the site exposure to vibration. Severe treatment‐resistant disease can occur, associated with significant disability. Therapy omalizumab, monoclonal IgG anti‐IgE antibody, has been shown be successful in several types urticaria. We report patient vibratory for whom all standard treatments urticaria, including failed show clinical benefit. Finally, ketotifen was tried, unexpectedly reduced...
The term anaphylaxis was coined by Charles Richet and Paul Portier when they tried to immunize dogs with actinia extracts, but after a repeated injection of small amount the toxin dog died within 25 min. new rapidly spread all over world. discovery phenomenon showed that immunization not only protection also harmful events could be induced. For this received Nobel Prize in 1913, he still believed condition lack poisonous effect substance. Already earlier similar clinical phenomena had been...
Anaphylaxis is a life-threatening emergency of which reliable epidemiological data are lacking. This study aimed to analyze how quickly patients presenting with anaphylaxis were treated in and whether treatment followed the European Academy Allergy Clinical Immunology (EAACI) guidelines.Patient collected between April 2009 2013. Emergency doctors completed questionnaire for adult at department (ED) St. Pierre hospital Brussels anaphylaxis. Inclusion criteria based on Sampson Data analyzed...
Abstract Background Chronic spontaneous urticaria (CSU) is characterized by the repeated occurrence of persistent hives and/or angioedema for ≥6 weeks, without specific external stimuli. H 1 ‐antihistamines have long been standard care CSU, but many patients remain uncontrolled even at 4× approved dose. Add‐on therapy with omalizumab has proven effective in clinical trials, little known about treatment Belgium. Objective To collect real‐world data on adults CSU Methods This was an...