Regina Treudler
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mast cells and histamine
- Eosinophilic Esophagitis
- Health and Medical Studies
- Cutaneous lymphoproliferative disorders research
- Pharmaceutical studies and practices
- Eosinophilic Disorders and Syndromes
- Occupational exposure and asthma
- Systemic Lupus Erythematosus Research
- Dermatological and Skeletal Disorders
- Skin and Cellular Biology Research
- Autoimmune and Inflammatory Disorders
- Ocular Diseases and Behçet’s Syndrome
- Entomological Studies and Ecology
- Nail Diseases and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Psoriasis: Treatment and Pathogenesis
Leipzig University
2016-2025
Charité - Universitätsmedizin Berlin
2004-2025
University Hospital Leipzig
2016-2025
Freie Universität Berlin
1997-2025
Humboldt-Universität zu Berlin
2024-2025
Klinik und Poliklinik für Neurologie
2009-2024
Fraunhofer Institute for Translational Medicine and Pharmacology
2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2024
Center for Interdisciplinary Studies
2023
University Medical Center
2021
The LIFE-Adult-Study is a population-based cohort study, which has recently completed the baseline examination of 10,000 randomly selected participants from Leipzig, major city with 550,000 inhabitants in east Germany. It first study this kind and size an urban population eastern part conducted by Leipzig Research Centre for Civilization Diseases (LIFE). Our objective to investigate prevalences, early onset markers, genetic predispositions, role lifestyle factors civilization diseases,...
Abstract Background Preventive measures to decrease the frequency and intensity of anaphylactic events are essential provide optimal care for allergic patients. Aggravating factors may trigger or increase severity anaphylaxis therefore need be recognized avoided. Objective To identify prioritize associated with an increased risk developing severe anaphylaxis. Methods Data from Anaphylaxis Registry (122 centers in 11 European countries) were used logistic regression models considering...
Intravenous LTLeukotriene NSAID Non-steroidal anti-inflammatory drugs PAF Platelet-activating factor s
Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients....
The persistently high prevalence of allergic diseases in Western industrial nations and the limited possibilities causal therapy make evidence-based recommendations for primary prevention necessary.
Food is one of the most common elicitors anaphylaxis, with an increasing incidence over recent years.
Abstract Background Anaphylaxis is the most severe manifestation of an IgE‐dependent allergy. Standardized acquired clinical data from large cohorts well‐defined cases are not available. The aim this study was to analyse symptom profile and risk factors anaphylaxis in a Central European cohort. Methods We patients Germany, Austria Switzerland who experienced allergic reaction defined by onset pulmonary and/or cardiovascular symptoms. were gained via online questionnaire 83 medical centres...
Background: Anaphylaxis is the most severe manifestation of a mast cell-dependent immediate reaction and may be fatal.According to data from Berlin region, its incidence 2-3 cases per 100 000 persons year.Methods: We evaluated anaphylaxis registry German-speaking countries for 2006-2013 protocols ADAC air rescue service 2010-2011 study triggers, clinical manifestations, treatment anaphylaxis.Results: The contained on 4141 patients, concerned 1123 patients.In registry, common triggers were...
The number of patients affected by allergies is increasing worldwide. resulting allergic diseases are leading to significant costs for health care and social systems. Integrated pathways needed enable comprehensive within the national ARIA (Allergic Rhinitis its Impact on Asthma) initiative develops internationally applicable guidelines respiratory diseases. serves improve with chronic In collaboration other international initiatives, associations patient organizations in field diseases,...
The COVID-19 pandemic dramatically disrupts health care around the globe. impact of on chronic urticaria (CU) and its management are largely unknown.To understand how CU patients affected by pandemic; specialists alter patient management; course in with COVID-19.Our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed consultations, remote treatment, changes medications, clinical consequences.The severely impairs care, less than 50% weekly numbers...
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Journal Article Cohort Profile: The LIFE-Adult-Study Get access Christoph Engel, Engel Institute for Medical Informatics, Statistics and Epidemiology, Leipzig University, Leipzig, GermanyLeipzig Research Centre Civilization Diseases, Germany Corresponding author. Haertelstrasse 16–18, 04107 Germany. E-mail: christoph.engel@imise.uni-leipzig.de https://orcid.org/0000-0002-7247-282X Search other works by this author on: Oxford Academic PubMed Google Scholar Kerstin Wirkner, Wirkner Samira...
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Hymenoptera venom (HV) is injected into the skin during a sting by such as bees or wasps. Some components of HV are potential allergens and can cause large local and/or systemic allergic reactions (SAR) in sensitized individuals. During their lifetime, ~ 3% general population will develop SAR following sting. This guideline presents diagnostic therapeutic approach to stings. Symptomatic therapy usually required after severe reaction, but specific diagnosis allergen immunotherapy (AIT) with...
Vegan diets are currently attracting a great deal of attention. However, avoiding animal-based foods restricts the diet and is associated with risks, extent medical implications which at present not sufficiently understood. Elimination represent usual therapeutic long-term management in presence food allergy. In order to understand risks vegan discuss these critically from perspective allergies, expertise nutritionist/dietitian this area indispensable. This position paper deals incentives...
Chronic spontaneous urticaria (CSU) is a relatively common skin disease associated with hives and angio-oedema. Eosinophils play role in CSU pathogenesis. Benralizumab, an anti-interleukin-5 receptor-α monoclonal antibody, has been shown to induce nearly complete depletion of eosinophils.