A5046737415- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Health and Medical Studies
- Dermatology and Skin Diseases
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Sinusitis and nasal conditions
- Immunodeficiency and Autoimmune Disorders
- Urticaria and Related Conditions
- Vitamin D Research Studies
- Pediatric health and respiratory diseases
- Biomedical and Chemical Research
- Eosinophilic Esophagitis
- Air Quality and Health Impacts
- Cystic Fibrosis Research Advances
- Olfactory and Sensory Function Studies
- Medical Practices and Rehabilitation
- Child Nutrition and Feeding Issues
- Therapeutic Uses of Natural Elements
- Entomological Studies and Ecology
- Dermatological diseases and infestations
- Hematological disorders and diagnostics
- Streptococcal Infections and Treatments
Zentrum für Rhinologie und Allergologie
2014-2023
Helios Dr. Horst Schmidt Kliniken Wiesbaden
2016-2017
Universitäts HNO Klinik Mannheim
2017
Heidelberg University
2012-2014
University Hospital Heidelberg
2012-2014
The number of patients affected by allergies is increasing worldwide. resulting allergic diseases are leading to significant costs for health care and social systems. Integrated pathways needed enable comprehensive within the national ARIA (Allergic Rhinitis its Impact on Asthma) initiative develops internationally applicable guidelines respiratory diseases. serves improve with chronic In collaboration other international initiatives, associations patient organizations in field diseases,...
Abstract Background The safety and tolerability of a mite allergoid subcutaneous allergen immunotherapy ( SCIT ) product was previously established. aim this study (EudraCT number: 2011–000393–61) to find the optimally safe effective dose by evaluating several dosages in patients with house dust HDM )‐induced allergic rhinoconjunctivitis ARC using titrated nasal provocation test TNPT ). Methods In total, 290 adult (148 females; 142 males) established allergy positive were randomized receive...
Abstract Background The number of patients affected by allergies is increasing worldwide. resulting allergic diseases are leading to significant costs for health care and social systems. Integrated pathways needed enable comprehensive within the national ARIA (Allergic Rhinitis its Impact on Asthma) initiative develops internationally applicable guidelines respiratory diseases. Methods serves improve with chronic In collaboration other international initiatives, associations patient...
Allergic rhinitis (AR) and asthma may affect health-related quality of life. However, national estimates on the life patients with AR or are lacking.
Introduction: Ambroxol (2-amino-3,5-dibromo-N-[trans-4-hydroxycyclohexyl]benzylamine), an over-the-counter product, is a mucoactive agent and has been used widely to treat both acute chronic respiratory diseases since 1978. This review aims provide overview of the clinical evidence available on use ambroxol in children with diseases. Data for this were obtained from published unpublished studies, real-world studies. Although conducted prior introduction Good Clinical Practice (GCP), these...
Background The purpose of this study was to investigate the effect MP‐AzeFlu on olfaction and interaction between severity allergic rhinitis olfactory improvement after therapy. Methods A prospective, multicenter, observational performed 47 patients with persistent rhinitis. Duration diagnosed classified using modified Allergic Rhinitis its Impact Asthma (ARIA) criteria proof allergen sensitization from positive skin‐prick tests, specific immonoglobulin E (IgE) in serum, nasal provocation...
Abstract Background Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality Life (HRQoL) patients in order identify statistically significant influencing factors determine HRQoL. Another assess data on cost-of-illness from statutory insurance perspective. Methods The EQ-5D-5L used evaluate patients’ To HRQoL, multinomial logistic regression analysis conducted using...
Zusammenfassung Hintergrund Die chronische Rhinosinusitis mit Nasenpolypen (CRSwNP) ist eine multifaktorielle entzündliche Erkrankung der Schleimhäute von Nase und Nasennebenhöhlen. Eine Typ-2-Inflammation als immunologischer Mechanismus wird häufigster Endotyp beschrieben. Der Anti-IL-4-/-IL-13-Antikörper Dupilumab seit Oktober 2019 Zusatztherapie zu intranasalen Glukokortikosteroiden für die Behandlung Erwachsener schwerer chronischer zugelassen, wenn systemische Glukokortikosteroide oder...
Zusammenfassung Hintergrund Die chronische Rhinosinusitis mit Nasenpolypen (CRSwNP) ist eine multifaktorielle entzündliche Erkrankung der nasalen und paranasalen Schleimhaut, oftmals Typ-2-Inflammation zugrunde liegt. Durch die Entwicklung von Biologika, in diese Entzündungsmechanismen eingreifen können, steht neuartige Therapiemöglichkeit zur Verfügung. Methoden Auf Grundlage des aktuellen Wissensstandes Immunologie CRSwNP Wirkung Biologika sowie deren mögliche unerwünschte Wirkungen werden...
Die chronische Rhinosinusitis mit Nasenpolypen (CRSwNP) ist eine multifaktorielle entzündliche Erkrankung, oftmals auf der Grundlage einer Typ-2-Inflammation. Für die Behandlung von Patienten schweren Ausprägung ohne ausreichendes Ansprechen Standardtherapie topischen nasalen Steroiden und/oder Zustand nach endonasaler Operation sind als Biologika aktuell Dupilumab und Omalizumab für Therapie zugelassen. Nachdem wir in früheren Publikation bereits entsprechende Hinweise gegeben haben, das...
Allergen immunotherapy (AIT) represents the only possibility of causal therapy for allergic respiratory diseases. Although prevailing high prevalence diseases and restrictions in daily lives patients, AIT is offered to a suboptimal number patients Germany.Insured with documented disease one largest statutory health insurances Germany, 'DAK-Gesundheit', were contacted by postal mail asked participate study. In case written consent, primary secondary data collected analysed. Patient...
Zusammenfassung Inhalationsallergien bei Kindern erfordern eine umfassende Diagnostik und konsequente Therapie. Das Behandlungsspektrum umfasst neben der Allergenkarenz die symptomatische Pharmakotherapie kausale Allergie-Immuntherapie (AIT). Kinder sind wichtige Zielgruppe für AIT, da sie aufgrund ihrer Langzeiteffekte sekundär-präventiven Eigenschaften den Verlauf Erkrankung nachhaltig beeinflussen kann.