Oliver Pfaar
A5034364156- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Olfactory and Sensory Function Studies
- Health and Medical Studies
- Sinusitis and nasal conditions
- Urticaria and Related Conditions
- Ocular Surface and Contact Lens
- Nasal Surgery and Airway Studies
- Pediatric health and respiratory diseases
- Inflammatory mediators and NSAID effects
- Inhalation and Respiratory Drug Delivery
- Eosinophilic Esophagitis
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Immunodeficiency and Autoimmune Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Delphi Technique in Research
- Advanced Chemical Sensor Technologies
Philipps University of Marburg
2018-2025
Universitätsklinikum Gießen und Marburg
2019-2025
Zentrum für Rhinologie und Allergologie
2012-2024
Goethe University Frankfurt
2024
Heidelberg University
2011-2023
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde
2022
Great Ormond Street Hospital for Children NHS Foundation Trust
2021
European Academy of Allergy and Clinical Immunology
2018-2020
American Academy of Allergy, Asthma and Immunology
2020
Klinik und Poliklinik für Kinder- und Jugendmedizin
2020
Abstract Allergic rhinoconjunctivitis (AR) is an allergic disorder of the nose and eyes affecting about a fifth general population. Symptoms AR can be controlled with allergen avoidance measures pharmacotherapy. However, many patients continue to have ongoing symptoms impaired quality life; pharmacotherapy may also induce some side‐effects. Allergen immunotherapy (AIT) represents only currently available treatment that targets underlying pathophysiology, it disease‐modifying effect. Either...
We have prepared this document, "Sublingual Immunotherapy: World Allergy Organization Position Paper 2013 Update", according to the evidence-based criteria, revising and updating chapters of originally published paper, 2009", available at http://www.waojournal.org. Namely, these comprise: "Mechanisms sublingual immunotherapy;" "Clinical efficacy immunotherapy" - reporting all data controlled trials after 2009; "Safety with recently Grading System for adverse reactions; "Impact immunotherapy...
Food allergy can result in considerable morbidity, impairment of quality life, and healthcare expenditure. There is therefore interest novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by European Academy Allergy Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy IgE-mediated Allergy, aims to provide evidence-based recommendations active...
Critical examination of the quality and validity available allergic rhinitis (AR) literature is necessary to improve understanding appropriately translate this knowledge clinical care AR patient. To evaluate existing literature, international multidisciplinary experts with an interest in have produced International Consensus statement on Allergy Rhinology: Allergic Rhinitis (ICAR:AR).Using previously described methodology, specific topics were developed relating AR. Each topic was assigned a...
Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal most frequently used tests, both
Abstract Background Allergen immunotherapy ( AIT ) has been thoroughly documented in randomized controlled trials RCT s). It is the only immune‐modifying and causal treatment available for patients suffering from I g E ‐mediated diseases such as allergic rhinoconjunctivitis, asthma insect sting allergy. However, there a high degree of clinical methodological heterogeneity among endpoints studies on , both subcutaneous sublingual SCIT SLIT ). At present, are no commonly accepted standards...
Visual analogue scales (VAS) are psychometric measuring instruments designed to document the characteristics of disease-related symptom severity in individual patients and use this achieve a rapid (statistically measurable reproducible) classification disease control. VAS can also be used routine patient history taking monitor course chronic such as allergic rhinitis (AR). More specifically, has been assess effectiveness AR therapy real life, both intermittent persistent disease.This...
Hymenoptera venom allergy is a potentially life-threatening allergic reaction following honeybee, vespid, or ant sting. Systemic-allergic sting reactions have been reported in up to 7.5% of adults and 3.4% children. They can be mild restricted the skin moderate severe with risk anaphylaxis. Patients should carry an emergency kit containing adrenaline autoinjector, H1 -antihistamines, corticosteroids depending on severity their previous reaction(s). The only treatment prevent further systemic...
Allergen immunotherapy (AIT) is an effective treatment for allergic rhinoconjunctivitis (AR) with or without asthma. It important to note that due the complex interaction between patient, allergy triggers, symptomatology and vaccines used AIT, some patients do not respond optimally treatment. Furthermore, there are no validated generally accepted candidate biomarkers predictive of clinical response AIT. Clinical management receiving AIT efficacy in randomised controlled trials drug...
Abstract Allergen immunotherapy ( AIT ) has been in use for the treatment of allergic disease more than 100 years. Asthma relies mainly on corticosteroids and other controllers recommended to achieve maintain asthma control, prevent exacerbations, improve quality life. is underused asthma, both children adults. Notably, patients with not adequately controlled pharmacotherapy (including biologics) represent an unmet health need. The European Academy Allergy Clinical Immunology developed a...
Abstract Nasal allergen challenge (NAC) is an important tool to diagnose allergic rhinitis. In daily clinical routine, experimentally, or when measuring therapeutic success clinically, nasal fundamental. It further one of the key diagnostic tools initiating specific immunotherapy. So far, national recommendations offered guidance on its execution; however, international divergence left many questions unanswered. These differences in literature caused EAACI initiate a task force answer unmet...
Abstract Severe asthma imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care pathways differences between national or regional Better understanding of the mechanisms has enabled stratified approach management severe asthma, supporting use targeted treatments with biologicals. However, there are still many issues that require further clarification. These include selection certain...
Abstract Allergic diseases are common and frequently coexist. Allergen immunotherapy ( AIT ) is a disease‐modifying treatment for IgE‐mediated allergic disease with effects beyond cessation of that may include important preventive effects. The European Academy Allergy Clinical Immunology EAACI has developed clinical practice guideline to provide evidence‐based recommendations the prevention (i) development comorbidities in those established diseases, (ii) first condition, (iii)...