- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Nasal Surgery and Airway Studies
- Respiratory and Cough-Related Research
- Olfactory and Sensory Function Studies
- Tracheal and airway disorders
- Obstructive Sleep Apnea Research
- Head and Neck Surgical Oncology
- Neuroscience of respiration and sleep
- Airway Management and Intubation Techniques
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Pediatric health and respiratory diseases
- Otitis Media and Relapsing Polychondritis
- Ocular Surface and Contact Lens
- Food Allergy and Anaphylaxis Research
- Dermatology and Skin Diseases
- Mast cells and histamine
- Craniofacial Disorders and Treatments
- Immune Response and Inflammation
- Cleft Lip and Palate Research
- Sleep and Wakefulness Research
- Urticaria and Related Conditions
- Otolaryngology and Infectious Diseases
University of Chicago
2015-2024
Comer Children's Hospital
2003-2024
Temple University
2024
Harvard University
2024
American Academy of Otolaryngology — Head and Neck Surgery
2024
Nationwide Children's Hospital
2023
University of Chicago Medical Center
2008-2021
Fondazione Lombardia per l’Ambiente
2017
John Wiley & Sons (United States)
2016
Stryker (United States)
2015
The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 2007. document contains chapters definitions classification, we now also proposed for difficult to treat rhinosinusitis, control disease better rhinosinusitis children. More emphasis placed diagnosis treatment acute rhinosinusitis. Throughout terms chronic without nasal polyps (CRSsNP) with (CRSwNP) are used further point out differences...
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012.A summary for otorhinolaryngologists. no immunosuppressants IV D saline irrigation Ib, data in single use yes symptomatic relief topical antibiotics anti-IL-5 unclear phytotherapy decongestant / oral mucolytics antihistamine allergic patients antimycotics -topical Ia (-) ** A(-) -systemic Ib (-)# $ anti leukotrienes anti-IgE * Some of these studies also included with CRS polyps.% short term shows one positive negative...
Objective Allergic rhinitis (AR) is one of the most common diseases affecting adults. It chronic disease in children United States today and fifth overall. AR estimated to affect nearly 1 every 6 Americans generates $2 $5 billion direct health expenditures annually. can impair quality life and, through loss work school attendance, responsible for as much $4 lost productivity Not surprisingly, myriad diagnostic tests treatments are used managing this disorder, yet there considerable variation...
Critical examination of the quality and validity available allergic rhinitis (AR) literature is necessary to improve understanding appropriately translate this knowledge clinical care AR patient. To evaluate existing literature, international multidisciplinary experts with an interest in have produced International Consensus statement on Allergy Rhinology: Allergic Rhinitis (ICAR:AR).Using previously described methodology, specific topics were developed relating AR. Each topic was assigned a...
Evidence suggests IgE may play a role in chronic rhinosinusitis (CRS). We sought to determine if treatment with monoclonal antibody against (omalizumab) is effective reducing CRS inflammation. performed randomized, double blind, placebo controlled clinical trial subjects despite (including surgery). Subjects were randomized receive omalizumab or for 6 months. The primary outcome was quantitative measurement of sinus inflammation on imaging. Secondary measures included quality life, symptoms,...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation (AAO‐HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Allergic Rhinitis. To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 14 recommendations developed address evaluation patients with allergic rhinitis, including performing interpretation diagnostic testing assessment documentation chronic conditions...
Evidence suggests IgE may play a role in chronic rhinosinusitis (CRS). We sought to determine if treatment with monoclonal antibody against (omalizumab) is effective reducing CRS inflammation. performed randomized, double blind, placebo controlled clinical trial subjects despite (including surgery). Subjects were randomized receive omalizumab or for 6 months. The primary outcome was quantitative measurement of sinus inflammation on imaging. Secondary measures included quality life, symptoms,...
The pattern of mediators and appearance cells that stain with alcian blue during human experimental early late phase allergic reactions suggest basophils accumulate in nasal secretions within hours local Ag stimulation. To further explore whether the histamine containing enter nose after challenge are mast or basophils, we studied their functional phenotypic characteristics. Approximately 24 h intranasal provocation subjects rhinitis, lavage was performed, were isolated for degranulation...
Microbes and allergens can stimulate the nasal mucosa, potentially leading to development of acute bacterial rhinosinusitis (ABRS). This study was designed determine if allergen exposure alters sinonasal microbiome.We performed a parallel observational healthy adults with seasonal allergic rhinitis (SAR; grass or tree, n = 20) nonallergic subjects (n 19). Microbiota specimens were obtained by endoscopy from middle meatus vestibule before during relevant season analyzed terminal restriction...
ICAR: Allergic Rhinitis Author Disclosure of Conflict Interest Conflicts Form for Authors International Forum Allergy & Rhinology-International Consensus Statement on and Rhinology: supplement Please note: The publisher is not responsible the content or functionality any supporting information supplied by authors. Any queries (other than missing content) should be directed to corresponding author article.
Chronic rhinosinusitis (CRS) disease control is a global metric of status for CRS. While there broad acceptance that it an important treatment goal, has been inconsistency in the criteria used to define CRS control. The objective this study was identify and develop consensus around essential assessment control.Modified Delphi methodology consisting three rounds review list 24 possible developed by 12-person steering committee. core authorship multidisciplinary EPOS 2020 guidelines invited...