Thomas Spindler
A5064919629- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Health and Medical Studies
- Dermatology and Skin Diseases
- Pediatric health and respiratory diseases
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Eosinophilic Esophagitis
- Voice and Speech Disorders
- Medical and Health Sciences Research
- Child and Adolescent Health
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Adolescent and Pediatric Healthcare
- Drug-Induced Adverse Reactions
- Vaccine Coverage and Hesitancy
- Psychology, Coaching, and Therapy
- Biomedical and Chemical Research
- Pharmaceutical studies and practices
- Tracheal and airway disorders
- Case Reports on Hematomas
- Aerodynamics and Acoustics in Jet Flows
- Cognitive Science and Education Research
Landwirtschaftlichen Zentrums Baden-Württemberg
2011-2024
Medizin Campus Bodensee
2023-2024
Hochgebirgsklinik Davos
2018-2023
Waldburg-Zeil Kliniken
2007-2017
Queen Elizabeth University Hospital
2016
KUKA (Germany)
2016
Universitätsbibliothek Johann Christian Senckenberg
2013
Koblenz University of Applied Sciences
2013
Daimler (Germany)
2001
Abstract Background Preventive measures to decrease the frequency and intensity of anaphylactic events are essential provide optimal care for allergic patients. Aggravating factors may trigger or increase severity anaphylaxis therefore need be recognized avoided. Objective To identify prioritize associated with an increased risk developing severe anaphylaxis. Methods Data from Anaphylaxis Registry (122 centers in 11 European countries) were used logistic regression models considering...
The persistently high prevalence of allergic diseases in Western industrial nations and the limited possibilities causal therapy make evidence-based recommendations for primary prevention necessary.
Food is one of the most common elicitors anaphylaxis, with an increasing incidence over recent years.
Zusammenfassung Das Management von Asthma hat sich in den letzten Jahrzehnten fundamental gewandelt. Die vorliegende Leitlinie zur Diagnostik und Therapie wurde für pneumologisch tätige Fachärztinnen Fachärzte entwickelt, welche detaillierte evidenzbasierte Informationen zu neuen diagnostischen therapeutischen Optionen benötigen. zeigt die neue Bedeutung der Biomarker, insbesondere Bluteosinophilen des exhalierten NO (FeNO), Algorithmen Asthma. Als erste Asthma-Leitlinie weltweit benennt...
Zusammenfassung Die vorliegende Leitlinie ist eine Neufassung und Aktualisierung der zur Diagnostik Therapie von Patienten mit Asthma, welche die bisher für den deutschen Sprachraum gültige Version aus dem Jahr 2006 ablöst. Fülle an neuen Erkenntnissen Pathophysiologie zu Phänotypen Asthma das erweiterte Spektrum diagnostischen therapeutischen Möglichkeiten bei dieser Erkrankung machte notwendig. Es werden sowohl Kinder Jugendliche als auch Erwachsene aktuellen, Evidenz-basierten...
The number of patients affected by allergies is increasing worldwide. resulting allergic diseases are leading to significant costs for health care and social systems. Integrated pathways needed enable comprehensive within the national ARIA (Allergic Rhinitis its Impact on Asthma) initiative develops internationally applicable guidelines respiratory diseases. serves improve with chronic In collaboration other international initiatives, associations patient organizations in field diseases,...
Summary This S3 guideline was created based on the European guideline, with special consideration of medical conditions in German‐speaking region and incorporating additions from previous German‐language version. The interdisciplinary commission consisted representatives German Dermatological Society, Professional Association Dermatologists, Austrian Society Dermatology Venereology, Swiss for Allergology Clinical Immunology, Pediatric Adolescent Medicine, Pediatricians Environmental...
Peanut allergy has a rising prevalence in high-income countries, affecting 0.5%-1.4% of children. This study aimed to better understand peanut anaphylaxis comparison other food triggers European children and adolescents.Data was sourced from the Anaphylaxis Registry via an online questionnaire, after in-depth review food-induced cases tertiary paediatric centre.3514 were reported between July 2007 - March 2018, 56% patients younger than 18 years. recorded 459 adolescents (85% all cases)....
Summary The present S3 guideline was created based on the European English‐language guideline, with special consideration given to medical conditions in German‐speaking region, and additions from previous German‐language version, accordance criteria of AWMF. This second part addresses systemic therapy atopic dermatitis (AD). It covers topics such as indication for children, adolescents, adult patients AD. Furthermore, it all medications approved AD, biologics dupilumab tralokinumab, Janus...
Abstract Background The number of patients affected by allergies is increasing worldwide. resulting allergic diseases are leading to significant costs for health care and social systems. Integrated pathways needed enable comprehensive within the national ARIA (Allergic Rhinitis its Impact on Asthma) initiative develops internationally applicable guidelines respiratory diseases. Methods serves improve with chronic In collaboration other international initiatives, associations patient...
Recently, epidemiological data shows an increase of childhood tuberculosis in Germany. In addition to this, drug resistant becomes more frequent. Therefore, diagnosis, prevention and therapy adolescence remain a challenge. Adult guidelines do not work for children, as there are age specific differences manifestation, risk progression diagnostic well therapeutic pathways.The German Society Pediatric Infectious Diseases (DGPI) has initiated consensus-based (S2k) process completed paediatric...
Abstract Background Cow's milk (CM) and hen's egg (HE) are leading triggers of anaphylaxis in early childhood. The aim this study was to identify clinical phenotypes therapeutic measures for CM (CMA) compared HE (HEA) children up 12 years age, based on a large pan‐European dataset from the European Anaphylaxis Registry. Methods Data 2007 2020 treatment 10 countries, as well Brazil, were analysed. two‐step cluster analysis used most frequent phenotypes. For each trigger, three clusters...
Food allergens are frequent causes of anaphylaxis. In particular in children and adolescents they the most elicitors severe allergic reactions, adults food rank third behind insect venom drugs. Since July 2006 reactions from Germany, Austria, Switzerland collected anaphylaxis registry. Currently 78 hospitals private practises connected. From until February 2009 1,156 were registered. Among (n = 187, age range 3 months to 17 years) triggers, comprising 58% cases. adult group 968, 18 - 85...
Zusammenfassung Das vorliegende Addendum zur Leitlinie Diagnostik und Therapie von Patienten mit Asthma (2017) ergänzt wichtige neue Erkenntnisse sowie zu neu für die des Asthmas zugelassenen Medikamenten. Es werden sowohl Kinder Jugendliche als auch Erwachsene aktuellen, Evidenz-basierten diagnostischen therapeutischen Empfehlungen dargelegt.
Patients with a history of anaphylaxis are at risk future anaphylactic reactions. Thus, secondary prevention measures recommended for these patients to prevent or attenuate the next reaction.Data from Anaphylaxis Registry were analyzed identify offered who experienced anaphylaxis. Our analysis included 7788 cases 10 European countries and Brazil.The varied across elicitors. A remarkable discrepancy was observed between in specialized allergy centers (84% prescribed adrenaline autoinjectors...
Abstract Peanuts are Leguminosae, commonly known as the legume or pea family, and peanut allergy is among most common food allergies cause of fatal reactions anaphylaxis. The prevalence increased 3.5-fold over past two decades reaching 1.4–2% in Europe United States. reasons for this increase likely multifaceted. Sensitization via skin appears to be associated with development atopic eczema infancy a high risk developing allergy. Until recently, only possible management strategy was strict...
Summary The extension of the approval dupilumab for treatment severe atopic dermatitis in children 6 months age and older Germany creates a potential conflict with administration live attenuated vaccines. According to product information, vaccines is contraindicated during ongoing therapy. This position paper, written by specialists pediatric immunology allergology from Switzerland, aims support pediatricians provide their patients best possible appropriate vaccinations based on currently...