A5000864962- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Eosinophilic Esophagitis
- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Pharmacovigilance and Adverse Drug Reactions
- Mast cells and histamine
- Dermatology and Skin Diseases
- Inflammatory mediators and NSAID effects
- Probiotics and Fermented Foods
- Climate Change and Health Impacts
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- Pharmaceutical studies and practices
Humboldt-Universität zu Berlin
2022-2025
Freie Universität Berlin
2022-2025
Charité - Universitätsmedizin Berlin
2022-2025
Städtisches Klinikum Dessau
2022
Food is one of the most common elicitors anaphylaxis, with an increasing incidence over recent years.
ABSTRACT Background Wheat is a well‐known elicitor of food allergy, but epidemiological data are limited. The aim this study was to investigate the prevalence wheat allergy in an unselected population adults and adolescents characterise clinical features cohort, as well those patients who experienced wheat‐induced anaphylaxis. Methods A population‐based cross‐sectional conducted. Fifteen thousand individuals aged 12–80 years were randomly selected, standardised questionnaire applied. If...
Acetylsalicylic acid (ASA) can exert proanaphylactic effects, but the extent of this phenomenon and its underlying mechanisms are undefined. Yet, low homeostatic prostaglandin E2 (PGE2) levels have been associated with anaphylaxis. In study, we investigated whether effect ASA is PGE2 dependent. We assessed in experimental anaphylaxis models, analyzed a large dataset patients anaphylaxis, performed titrated allergen challenges ASA-treated allergic individuals. Registry data indicated an...
The anaphylaxis registry collects structured data across Europe regarding elicitors, accompanying circumstances and other diseases as well the treatment of severe allergic reactions. By March 2024, 16,988 cases had been registered, which ~ 1/3 were children 2/3 adults. Among children, boys are most frequent affected, while among adults, women frequently affected. common elicitors depend on age continue to be dominated by food allergens in insect venom occurrence without skin symptoms is not...
Abstract Background Epidemiologic data on occupational anaphylaxis is scarce, and there a need of more knowledge about work‐related anaphylactic episodes. Methods Based the Anaphylaxis Registry, we identified cases related to exposure analyzed elicitors, demographics, severity clinical reaction management. Results Since 2017, 5851 with an information relation episode were registered whereby 225 (3.8%) assigned be caused by allergen. The vast majority these insects ( n = 186, 82.7%) followed...
Peanut allergy is a frequent cause of food and potentially life-threatening. Within this interdisciplinary research approach, we aim to unravel the complex mechanisms peanut allergy. As first step were applied in an exploratory manner analysis allergic versus non-allergic controls.
Food allergy is a growing health concern with prevalence of 2%-3% in the adult population Europe. Non-immune-mediated food hypersensitivities, which include reactions after ingestion additives, affect 1% adults and may resemble IgE-induced allergic without identifiable immunologic sensitization. A double-blind placebo-controlled challenge (DBPCFC) gold standard for diagnosis any hypersensitivity.We analysed large group patients suspected hypersensitivity, who had undergone DBPCFC, to better...
This prospective cohort study of 16,943 consecutive patients compared phase angle (PhA, foot-to-hand at 50 kHz) and subjective global assessment (SGA) to predict outcomes length hospital stay (LOS) in-hospital mortality in risk malnutrition (NRS-2002 ≥ 3). In 1505 patients, the independent effects on LOS were determined by competing analysis logistic regression. model I, including influence factors age, sex, BMI, diagnoses, malnourished (SGA B C) had a lower chance for regular discharge (HR...
Hymenoptera venom is one of the most frequent causes anaphylaxis. Studies from adults indicate clinical profiles and risk factors venom-induced anaphylaxis (VIA). Much less known about pediatric VIA.