A5044209980- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Mast cells and histamine
- Pharmaceutical studies and practices
- Cardiac electrophysiology and arrhythmias
- Immunodeficiency and Autoimmune Disorders
- Autoimmune Bullous Skin Diseases
- Occupational exposure and asthma
- Insect and Pesticide Research
- Respiratory and Cough-Related Research
- Pediatric health and respiratory diseases
- Monoclonal and Polyclonal Antibodies Research
- Atrial Fibrillation Management and Outcomes
- Biomedical and Chemical Research
- Pharmacovigilance and Adverse Drug Reactions
- Inflammatory mediators and NSAID effects
- Polyamine Metabolism and Applications
- Syphilis Diagnosis and Treatment
- Chemotherapy-related skin toxicity
- Cutaneous Melanoma Detection and Management
Medical University of Vienna
2008-2024
Allergiezentrum Wien West
2001-2022
FH Campus Wien
2016-2022
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2020
Johannes Gutenberg University Mainz
2020
Charité - Universitätsmedizin Berlin
2020
Zentrum für Rhinologie und Allergologie
2020
University Medical Center Freiburg
2017-2019
Vienna General Hospital
2017
Donauspital
2013
Skin prick testing is an essential test procedure to confirm sensitization in IgE-mediated allergic disease subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food drug allergy. This manuscript reviews the available evidence including Medline Embase searches, abstracts of international allergy meetings position papers from world literature. The recommended method includes appropriate use specific allergen extracts, positive negative controls, interpretation...
Background: Skin prick testing is the standard for diagnosing IgE‐mediated allergies. However, different allergen extracts and procedures have been applied by European allergy centres. Thus, it has difficult to compare results from centres or studies across Europe. It was, therefore, crucial standardize harmonize in diagnosis treatment within Aims: The Global Asthma Allergy Network (GA²LEN), with partners collaborating Europe, was a unique position take on this task. current study first...
Skin prick testing is the standard for diagnosing IgE-mediated allergies. A positive skin reaction, however, does not always correlate with clinical symptoms. large database from a Global Asthma and Allergy European Network (GA(2)LEN) study data on relevance was used to determine of sensitizations against 18 most frequent inhalant allergens in Europe. The population consisted patients referred one 17 allergy centres 14 countries (n = 3034, median age 33 years). aim assess test reactions...
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Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients....
Although downregulation of L-type Ca2+ current (I(Ca,L)) in chronic atrial fibrillation (AF) is an important determinant electrical remodeling, the molecular mechanisms are not fully understood. Here, we tested whether reduced I(Ca,L) AF associated with alterations phosphorylation-dependent channel regulation.We used whole-cell voltage-clamp technique and biochemical assays to study regulation expression myocytes tissue from 148 patients sinus rhythm (SR) AF. Basal at +10 mV was smaller than...
Skin prick testing (SPT) is the standard method for diagnosing allergic sensitization but to some extent performed differently in clinical centres across Europe. There would be advantages harmonizing panels of allergens used different European countries, both purposes and research, especially with increasing mobility within Europe current trends botany agriculture. As well as improving diagnostic accuracy, this allow better comparison research findings allergy centres. We have compared SPT...
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Hymenoptera venom (HV) is injected into the skin during a sting by such as bees or wasps. Some components of HV are potential allergens and can cause large local and/or systemic allergic reactions (SAR) in sensitized individuals. During their lifetime, ~ 3% general population will develop SAR following sting. This guideline presents diagnostic therapeutic approach to stings. Symptomatic therapy usually required after severe reaction, but specific diagnosis allergen immunotherapy (AIT) with...
Tyrosine phosphorylation and activation of the transcription factor Stat5 occur in response to stimuli like granulocyte-macrophage colony-stimulating factor, interleukin-3, or erythropoietin that stimulate both proliferation differentiation hematopoietic cells. It is unclear whether part a proliferative events leading cellular differentiation. Here we report agents promoting but not cells, phorbol ester types interferons (IFNs), activate promonocytic U937 Both IFN caused tyrosine DNA binding...
Patch testing was done on 2776 consecutive patients (76.5% female) with a locally revised standard series of 34 contact allergens and the results analyzed for age- gender-specific differences. At least one positive epicutaneous test reaction occurred in 48.9% patients. Nickel (20.9%), ethylmercuric chloride (13.2%), thimerosal (11.8%), fragrance mix (9.3%), metallic mercury (8.9%), palladium (5.8%), balsam Peru (3.8%), copper (3.7%), cobalt (3.3%), chromium (2.3%) were 10 most important...
Background: Currently, the diagnosis of IgE‐mediated allergy is based on allergen‐specific history and diagnostic procedures using natural allergen extracts for in vivo vitro tests. Objective: The aim study was to comparatively analyse a new component‐based allergen‐microarray ‘quasi‐standard’ ImmunoCAP ® their clinical relevance patients with allergic rhinoconjunctivitis five aeroallergens [house dust mite (HDM), cat dander, birch, grass mugwort pollen] prospective, double‐centre study....
The number of allergens to be tested in order identify sensitized patients is important have the most cost-effective approach epidemiological studies.To define minimal and type skin prick test (SPT) required a patient as using results new Pan-European GA(2)LEN study.In large multicenter (17 centers 14 countries) based study, standardized panel 18 has been procedure. Conditional allowed determine selection.Among 3034 involved, 1996 (68.2%) were at least one allergen. Overall, eight (grass...
Within a large prospective study, the Global Asthma and Allergy European Network (GA(2) LEN) has collected skin prick test (SPT) data throughout Europe to make recommendations for SPT in clinical settings.To improve interpretation of results inhalant allergens by providing quantitative decision points.The GA(2) LEN study with 3068 valid sets was used investigate relationship between patient-reported relevance each 18 as well wheal size physician-diagnosed allergy (rhinitis, asthma, atopic...
Abstract In the Mediterranean area, lipid transfer proteins ( LTP s) are important causes of plant‐food allergies often associated with severe allergic reactions. There, peach (Pru p 3) seems to be primary sensitizer, whereas in Central Europe, little is known about importance sensitization. this region, allergen extract‐based diagnosis complicated by co‐sensitization Bet v 1, major birch pollen allergen, its cross‐reactive food allergens, and profilins. We investigated role sensitization...