A5042702224- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Respiratory and Cough-Related Research
- Pharmaceutical studies and practices
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Pediatric health and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Immunodeficiency and Autoimmune Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cystic Fibrosis Research Advances
- Eosinophilic Esophagitis
- Pharmacovigilance and Adverse Drug Reactions
- Respiratory viral infections research
- Dermatology and Skin Diseases
- Blood disorders and treatments
- Genetic and Kidney Cyst Diseases
- Vitamin D Research Studies
- Infant Health and Development
- Genetic Syndromes and Imprinting
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Autoimmune Bullous Skin Diseases
Mersin Üniversitesi
2016-2025
Massachusetts Eye Research and Surgery Institute
2023
Hacettepe University
2003-2006
Ankara University
1994
Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients....
Summary Background Anaphylaxis is a serious and potentially lethal systemic reaction affecting more than one organ or system. Objective We aimed to describe the demographic characteristics, clinical features, causes, settings, administered therapy in T urkish children. Methods This retrospective, case note study included all children referred outpatient clinics of P ediatric A llergy D epartments participating centres from 1 J uly 1999 30 une 2009 for investigation anaphylaxis who were seen...
Objective: Lung function tests have attracted interest for the diagnosis and follow-up of childhood asthma in recent years. For patients who cannot perform forced expiratory maneuvers, impulse oscillometry (IOS), performed during spontaneous breathing, may be an alternative tool. Methods: Thirty-five acute, 107 stable asthmatic 103 healthy children presented to our clinic IOS followed by spirometry before after salbutamol inhalation. The mean baseline reversibility parameters were compared...
Emergence of new environmental risk factors, and/or loss protective factors a traditional lifestyle may explain the increase, or variations in prevalence allergic diseases. The aim this study was to delineate and spectrum of, reveal causal for atopic sensitization among heterogenous cohort Turkish children, first time our country. design adhered International Study Asthma Allergies Childhood (ISAAC) phase II protocol. A self‐administered parental questionnaire about demographic...
Rhinitis is a common problem with important comorbidities. In order to search the association between rhinitis, allergic phenotypes and other risk factors in Turkish children, parental questionnaire about diseases factors, skin prick test (SPT) 13 inhalant allergens were performed population‐based sample of 2774 children aged 9–11 yr. Bronchoprovocation testing hypertonic saline (HS)and total IgE analysis limited subsample 350 children. was defined as sneezing, rhinorrhea, or nasal...
Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently encountered in daily clinical practice. The aim of this study was determine the confirmation rates, risk factors NSAID hypersensitivity children and try classify them with a standardized diagnostic protocol.All patients suspicion NSAID-induced were evaluated European Network for drug Allergy (ENDA) recommendations. classified as selective responders (SRs) or cross-intolerant (CI) depending on provocation test...
BACKGROUND Recent evidence about the various effects of vitamin D (vit D) on innate and adaptive immunity has led to a search for role vit in asthma. It is postulated that decrease cathelicidin, multifunctional host defense molecule, production due low status may predispose infectious complications children with OBJECTIVE The aim this study was determine association D, D-binding protein (VDBP) cathelicidin acute asthma attacks among allergic METHODS This prospective included 35 patients...
Objective: Transcobalamin II deficiency is a rare autosomal recessive disease characterized by decreased cobalamin availability, which in turn causes accumulation of homocysteine and methylmalonic acid.The presenting clinical features are failure to thrive, diarrhea, megaloblastic anemia, pancytopenia, neurologic abnormalities, also recurrent infections due immune abnormalities early infancy. Materials Methods:Here, we report the laboratory six children with transcobalamin who were all...
Although it is the most common lower respiratory infection of infancy, optimal treatment for acute bronchiolitis still controversial. The aim this study was to compare early and late effects nebulized L-epinephrine (EPI) intramuscular dexamethasone (DEX) combination therapy with salbutamol (SAL) bronchodilators alone in outpatients bronchiolitis.A total 69 infants aged 2-21 months who were admitted Pediatrics Department Faculty Medicine, Mersin University, included a randomized,...
There are scarce data about the role of vitamin D (vitD) in asthma control related to seasons and other confounders.To investigate seasonal relationship between vitD levels control, lung function tests (LFTs) cytokines during a 1-year period, among 7-17-year-old asthmatic children.Thirty patients with house dust mite monosensitization were evaluated 3 monthly previous month's health lifestyle factors test (ACT), spirometry bronchial provocation for year. Serum vitD, binding protein (VDBP),...
Airway hyperresponsiveness (AHR) is a hallmark of asthma. Methacholine challenge test which mostly used to confirm AHR not routinely available. The aim this study was investigate the predictive values fractional exhaled nitric oxide (FeNO), impulse oscillometry (IOS), and plethysmography for assessment in children with well-controlled asthma.60 controlled allergic asthma aged 6-18 years participated study. FeNO measurement, spirometry, IOS, were performed. done assess AHR. PC20 dose response...