Semra Demir
A5032680201- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mast cells and histamine
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Education Practices and Challenges
- Contact Dermatitis and Allergies
- Educational Methods and Analysis
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Teacher Professional Development and Motivation
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pharmaceutical studies and practices
- Immunodeficiency and Autoimmune Disorders
- Hemophilia Treatment and Research
- Science Education and Pedagogy
- Pediatric health and respiratory diseases
- Atherosclerosis and Cardiovascular Diseases
- Educational Leadership and Administration
- Values and Moral Education
- Pathogenesis and Treatment of Hiccups
- Systemic Lupus Erythematosus Research
Istanbul University
2016-2025
Dokuz Eylül University
2023
Institute of Educational Sciences
2023
University of Mississippi Medical Center
2021
State Street (United States)
2021
American College of Allergy, Asthma and Immunology
2021
Şişli Etfal Eğitim ve Araştırma Hastanesi
2019
Fatih University
2019
Yedikule Teaching Hospital
2019
Sağlık Bilimleri Üniversitesi
2018
Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients....
The COVID-19 pandemic dramatically disrupts health care around the globe. impact of on chronic urticaria (CU) and its management are largely unknown.To understand how CU patients affected by pandemic; specialists alter patient management; course in with COVID-19.Our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed consultations, remote treatment, changes medications, clinical consequences.The severely impairs care, less than 50% weekly numbers...
Background: Hypersensitivity reactions (HRs) to iron agents are increasing in parallel with increased use of preparations. Objective: We aimed evaluate the clinical features and our previous desensitization protocol patients immediate hypersensitivity (IHR) agents. Methods: screened medical records 96 a history IHRs oral or intravenous (IV) evaluated diagnostic test results. Furthermore, we assessed safety success rate protocol. Results: Forty-seven had preparations, whereas 49 IV Skin-prick...
Background: Immediate hypersensitivity reactions (IHR) to ciprofloxacin can be caused by Mas-related G-protein coupled receptor X2 (MRGPRX2) as well immunoglobulin E (IgE)-dependent mechanisms. When considering the complexity of Patho mechanism, there are doubts with regard adequacy conventional basophil activation test (BAT) in diagnosing fluoroquinolone-induced IHR. Our aim was present a BAT method that relies on specifically evaluating basophils expressing MRGPRX2 increase diagnosis rate...
Cold urticaria (ColdU), that is, the occurrence of wheals or angioedema in response to cold exposure, is classified into typical and atypical forms. The diagnosis ColdU relies on whealing local stimulation testing (CST). It can also manifest with cold-induced anaphylaxis (ColdA). We aimed determine risk factors for ColdA ColdU.An international, cross-sectional study COLD-CE was carried out at 32 centers reference excellence (UCAREs). Detailed history taken CST an ice cube and/or TempTest®...
The consensus document for hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) proposed by the European Network Drug Allergy (ENDA) interest group (2011) was revised in 2013. We aimed evaluate usability of latest NSAID classification ENDA.A total 370 patients with a history NSAIDs among 1250 outpatients referred suspected drug allergy between July 2013 and June 2014 were evaluated, 308 who confirmed as having included this study. After confirming diagnosis,...
Patients with systemic lupus erythematosus (SLE) have increased rates of cardiovascular disease (CVD) that are one the major causes mortality. The aim this study was to determine frequencies metabolic syndrome (MetS) and CVD in SLE patients investigate link between these clinical features SLE.A total 311 were consecutively assessed for cumulative organ damage (SDI/SLICC scores), history MetS as defined by National Cholesterol Educational Program Adult Treatment Panel III (NCEP ATP III)....
National data on asthma characteristics and the factors associated with uncontrolled seem to be necessary for every country. For this purpose, we developed Turkish Adult Asthma Registry patients aiming take a snapshot of our patients, thereby assigning unmet needs niche areas intervention.Case entries were performed between March 2018 2022. A web-based application was used record data. Study outcomes demographic features, disease characteristics, control levels, phenotypes.The registry...
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
Objective The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess differences between obese and non-obese patients with asthma.
Background: The role of Blastocystis spp. subtypes (STs) in chronic spontaneous urticaria (CSU) and the impact eradication are unclear. Objective: To investigate STs CSU on disease activity. Methods: Stool samples from 295 patients 38 healthy controls (HCs) were searched for by direct microscopy. Fifty-seven 12 HCs analyzed ST distribution DNA sequencing. sequencing was only performed detected Real Time (RT)-polymerase chain reaction (PCR). with formed groups A B, respectively....
Abstract Background Hereditary angioedema (HAE) is a rare, potentially life-threatening condition that requires accessible and reliable information. YouTube has emerged as significant source of health-related content, offering valuable insights while posing the risk misinformation warrants caution among users. The aim this study was to evaluate popularity, reliability, understandability, actionability, overall quality videos related HAE. Method A search conducted on using term “hereditary...
Considerable overlaps exist between asthma phenotypes and the clinical significance of these remains undetermined. The objective this study is to analyze characteristics overlap using data from Turkish Adult Asthma Registry (TAAR). This cross-sectional registry included 2053 adult patients (74.8% female) with asthma. Overall, 39.3% (n = 697) had allergic-eosinophilic (AE), 26.0% 461) allergic-non-eosinophilic (ANE), 21.3% 377) non-allergic-eosinophilic (NAE), 13.4% 237)...
Abstract Background/Aim Misdiagnosis of hereditary angioedema (HAE) leads to inappropriate management the attacks. A scoring system that anticipates diagnosis can be beneficial for clinicians who are unfamiliar with angioedema. This study aims develop a practical use during acute attacks predict HAE in patients recurrent (RAE). Method To HAE, nine experts unanimously identified five predictive items (PIs); absence urticaria, presence abdominal pain episodes, family history, early onset and...
Abstract Objectives It is aimed to assess how physicians use chest imaging in asthma and the relationship between pathological findings related disease characteristics radiological of asthmatic patients. Background The daily practice its contribution management are not well defined. common investigate pathologies that cause respiratory symptoms evaluate differential diagnoses In this study, as a subanalysis Turkish Adult Asthma Registry, outcomes patients were examined. Methods Between March...
Purpose: Reports evaluating diagnosis and cross reactivity of quinolone hypersensitivity have revealed contradictory results.Furthermore, there are no reports investigating the cross-reactivity between gemifloxacin (GFX) others.We aimed to detect usefulness diagnostic tests reactions quinolones evaluate different including latest GFX.Methods: We studied 54 patients (mean age 42.31±10.39years; 47 female) with 57 due 10 nonatopic tolerable control subjects.A detailed clinical history, skin...
Abstract Background Oral immunotherapy (OIT) is a promising treatment for food allergies. Our aim was to establish the long‐term safety and efficacy of novel red meat (RM) OIT in galactose‐alpha‐1,3‐galactose (alpha‐gal) allergy adults. Methods Out 20 patients with confirmed RM allergy, five (41.66%) underwent an early OIT, seven (58.33%) delayed protocol eight who were not desensitized formed patient control group. 15 27 day early‐onset delayed‐onset alpha‐gal administered, respectively....
Studies on real-life adherence to subcutaneous allergen immunotherapy (SCIT) for respiratory allergy are scarce. The aim of this study was evaluate SCIT.The patients prescribed SCIT allergic rhinitis and/or asthma in 2009-2011 were contacted 2014 and asked whether they completed at least the 3 years suspended treatment 2 months. Total Symptom Score-6, visual analog scale (VAS), control test (ACT), medication scores, quality life (QoL) satisfaction scores with VAS obtained before initiation...
Chronic urticaria (CU) predominantly affects women, and sex hormones can modulate disease activity in female CU patients. As of now, the impact pregnancy on is largely unknown.To analyze course features during after pregnancy.PREG-CU an international, multicenter study Urticaria Centers Reference Excellence (UCARE) network. Data were collected via a 47-item questionnaire completed by patients, who became pregnant within last 3 years.A total 288 pregnancies patients from 13 countries analyzed...