A5087084947- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- IL-33, ST2, and ILC Pathways
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Contact Dermatitis and Allergies
- Protease and Inhibitor Mechanisms
- Transgenic Plants and Applications
- Immune Cell Function and Interaction
- Adrenal Hormones and Disorders
- Cytokine Signaling Pathways and Interactions
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
- T-cell and B-cell Immunology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Exercise and Physiological Responses
- Genetic Associations and Epidemiology
- Blood groups and transfusion
- Pharmaceutical studies and practices
- Autoimmune Bullous Skin Diseases
- Gut microbiota and health
- Blood Coagulation and Thrombosis Mechanisms
University of Lübeck
2016-2025
University Hospital Schleswig-Holstein
2016-2025
Kiel University
2013-2024
Clinical Research Center Kiel
2016-2023
ENT and Allergy
2006-2023
Elliot Hospital
2022-2023
University of Leicester
2022-2023
Délégation Paris 6
2022-2023
RELX Group (United States)
2023
Medizinische Hochschule Hannover
2022
Environmental factors such as tobacco smoking may have long-lasting effects on DNA methylation patterns, which might lead to changes in gene expression and a broader context the development or progression of various diseases. We conducted an epigenome-wide association study (EWAs) comparing current, former never smokers from 1793 participants population-based KORA F4 panel, with replication 479 F3 carried out by 450K BeadChip genomic obtained whole blood. observed wide-spread differences...
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool comprehensively explore gene regulatory networks investigate effects variation at molecular level. Serum metabolite concentrations allow direct readout biological processes, specific metabolomic signatures with complex diseases such as Alzheimer's disease cardiovascular metabolic disorders been shown. There are well-known correlations between sex incidence, prevalence, age...
Abstract Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease. The diagnosis made using evaluated clinical criteria. Disease activity and burden are best measured with composite score, assessing both objective subjective symptoms, such as SCORing Dermatitis (SCORAD). AD management must take into account pathogenic variabilities, the patient’s age also target flare prevention. Basic therapy includes hydrating barrier‐stabilizing topical treatment universally applied,...
To cite this article : Jungersted JM, Scheer H, Mempel M, Baurecht Cifuentes L, Høgh JK, Hellgren LI, Jemec GBE, Agner T, Weidinger S. Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema. Allergy 2010; 65 911–918. Abstract Background: Prior to the discovery of ( FLG ) mutations, evidence for an impaired dermatitis (AD) has been documented, changes ceramide profile, altered pH increased trans‐epidermal water loss (TEWL) AD have reported. Until...
Little is known on the current global prevalence of atopic dermatitis (AD) in pediatric population.To estimate real-world AD population and by disease severity.This international, cross-sectional, web-based survey children adolescents (6 months to <18 years old) was conducted following 18 countries: North America (Canada, United States), Latin (Argentina, Brazil, Columbia, Mexico), Europe (France, Germany, Italy, Spain, Kingdom), Middle East Eurasia (Israel, Saudi Arabia, Turkey, Arab...
High levels of serum IgE are considered markers parasite and helminth exposure. In addition, they associated with allergic disorders, play a key role in anti-tumoral defence, crucial mediators autoimmune diseases. Total is strongly heritable trait. genome-wide association study (GWAS), we tested 353,569 SNPs for 1,530 individuals from the population-based KORA S3/F3 study. Replication was performed four independent samples (total n = 9,769 individuals). Functional variants gene encoding...