A5079050321- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Eosinophilic Esophagitis
- Inhalation and Respiratory Drug Delivery
- Telemedicine and Telehealth Implementation
- Restraint-Related Deaths
- Cytomegalovirus and herpesvirus research
- Insect and Pesticide Research
- Herpesvirus Infections and Treatments
- Mast cells and histamine
- Infectious Encephalopathies and Encephalitis
- Pituitary Gland Disorders and Treatments
- Immune Cell Function and Interaction
- Gastrointestinal motility and disorders
- SARS-CoV-2 and COVID-19 Research
- Adrenal and Paraganglionic Tumors
- Gut microbiota and health
- Peripheral Artery Disease Management
- Advanced Differential Geometry Research
- Drug Solubulity and Delivery Systems
Azienda Usl Toscana Centro
2018-2023
Nuovo Ospedale San Giovanni di Dio
2020-2023
Azienda Ospedaliero-Universitaria Careggi
2010-2018
Centre Hospitalier Universitaire de Montpellier
2016-2017
Ospedale del Ceppo
2015-2016
Italian Society of Physiotherapy
2013
University of Florence
2007-2013
Hôpital Lapeyronie
2012
Abstract In less than half a century, allergy, originally perceived as rare disease, has become major public health threat, today affecting the lives of more 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting budgets systems. More disturbingly, its prevalence impact are on rise, development that been associated with environmental lifestyle changes accompanying continuous process urbanization globalization. Therefore, there is an urgent need...
IgE sensitization tests, such as skin prick testing and serum-specific IgE, have been used to diagnose IgE-mediated clinical allergy for many years. Their prime drawback is that they detect which only loosely related allergy. Many patients therefore require provocation tests make a definitive diagnosis; these are often expensive potentially associated with severe reactions. The likelihood of can be semi-quantified from an test results. This relationship varies though according the patients'...
Abstract Insect venom allergy is the most frequent cause of anaphylaxis in Europe and possibly worldwide. The majority systemic allergic reactions after insect stings are caused by Hymenoptera, among these, vespid genera induce sting (SSR). Honey bees second leading SSR. Depending on global region, other Hymenoptera such as different ant responsible for Widely distributed hornets bumblebees or local bee rarely Hematophagous insects mosquitoes horse flies usually (large) while SSR...
Abstract Efficacious, effective and efficient communication between healthcare professionals (HCP) patients is essential to achieve a successful therapeutic alliance. Telemedicine (TM) has been used for decades but during the COVID‐19 pandemic its use become widespread. This position paper aims describe terminology most important forms of TM among HCP review existing studies on uses asthma allergy. Besides, advantages risks are discussed, concluding that application reduces costs time both,...
The therapeutic efficacy of bone marrow mononuclear cells (BM-MNC) autotransplantation in critical limb ischemia (CLI) has been reported. Variable proportions circulating monocytes express low levels CD34 (CD14+CD34lowcells) and behave vitro as endothelial progenitor (EPCs). aim the present randomized clinical trial was to compare safety effects enriched EPCs (ECEPCs) with BM-MNC administration.Methods Results:ECEPCs (obtained from non-mobilized peripheral blood by immunomagnetic selection...
Natural killer (NK) cells play a fundamental role in innate and early phases of adaptive immunity against viral infections, both humans animal models. To date, NK cell deficiencies patients with severe herpetic infections have been reported single cases, their as predisposing factor is still controversial. Five children affected by encephalitis were consecutively admitted to the Anna Meyer Children's Hospital Florence (Italy) between 2003 2005. We therefore investigated presence consecutive...
Food allergen immunotherapy (FA-AIT) practice is known to vary globally. This project aims identify and characterize European centres performing FA-AIT.An EAACI task force conducted an online survey gather relevant information regarding FA-AIT setting-specific resources after reviewing the published literature congress abstracts throughout Europe.We identified 102 in 18 countries; only Spain (n = 39) France 16) had ≥10 such centres. Overall, most facilities were hospital-based (77.5%),...
Adverse reactions to iodinated contrast media (ICM) are reported in 1%-3% of diagnostic procedures.They represent a relevant problem involving patients' safety as well costs for healthcare systems.Premedication with antihistamines and corticosteroids is still widely used, but evidence its efficacy lacking there risk under-estimation possible severe adverse ICM those who undergo premedication.Data from 98 patients previous reaction that consecutively referred our unit between 2015 2018 were...
Rhinitis is often the first symptom of allergy but frequently ignored and classified as a nuisance condition. Ironically it has greatest socioeconomic burden worldwide caused by its impact on work daily life. However, patients appear reticent to seek professional advice, visiting their doctor only when symptoms become 'intolerable' usual therapy proves ineffective. Clearly, it's time for new more effective allergic rhinitis treatments. MP29-02 (Dymista®; Meda, Solna, Sweden) class medication...
The second-generation antihistamine rupatadine is a new long-acting and non-sedating drug that exerts potent dual-antagonist activity towards the histamine H1 receptor PAF receptor. Rupatadine prescribed for relief of symptoms seasonal perennial allergic rhinitis in treatment chronic urticaria. Clinical trials have shown rupatadine, which shows rapid onset action prolonged duration activity, effective well tolerated. Safety data indicate does not affect cardiovascular system, without...
Irritable bowel syndrome (IBS) is a very common chronic functional disorder of the lower gastrointestinal tract. It tipically includes and/or recurrent abdominal pain/discomfort, which can be relieved by defecation, and alteration stool form or frequency. Probiotics have been proposed as therapeutic approach in several pathologic conditions tract associated with dysbiosis, including IBS. In this observational study we investigated efficacy symbiotic formulation (SynGut TM ), composed four...